Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 3, Pages -Publisher
MDPI
DOI: 10.3390/ijms22031144
Keywords
inflammation; autoimmune disease; immunomodulation; exosome
Funding
- Korea Bio Grand Challenge program through the National Research Foundation of Korea [NRF-2018M3A9H3020844]
- BioYouCell
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Exosomes, as an advanced therapeutic strategy for treating an overactive immune system, are gaining attention and have the potential to be applied in the treatment of various inflammatory and autoimmune diseases, showing promising prospects for the future.
Immunomodulation is on the cusp of being an important therapy for treating many diseases, due to the significant role of the immune system in defending the human body. Although the immune system is an essential defense system, overactivity can result in diverse sicknesses such as inflammation and autoimmune disease. Exosomes are emerging as a state-of-the-art therapeutic strategy for treating an overactive immune system. Thus, in this review, we will thoroughly review therapeutic applications of exosomes in various inflammatory and autoimmune diseases. Finally, issues for an outlook to the future of exosomal therapy will be introduced.
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