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UBE2E Ubiquitin-conjugating Enzymes and Ubiquitin Isopeptidase Y Regulate TDP-43 Protein Ubiquitination
Friederike Hans et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Futsch/MAP1B mRNA Is a Translational Target of TDP-43 and Is Neuroprotective in a Drosophila Model of Amyotrophic Lateral Sclerosis
Alyssa N. Coyne et al.
JOURNAL OF NEUROSCIENCE (2014)
Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models
Hyung-Jun Kim et al.
NATURE GENETICS (2014)
Reduced C9orf72 protein levels in frontal cortex of amyotrophic lateral sclerosis and frontotemporal degeneration brain with the C9ORF72 hexanucleotide repeat expansion
Adrian J. Waite et al.
NEUROBIOLOGY OF AGING (2014)
Aggregate formation prevents dTDP-43 neurotoxicity in Drosophila melanogaster eye
Lucia Cragnaz et al.
NEUROBIOLOGY OF DISEASE (2014)
Chronological requirements of TDP-43 function in synaptic organization and locomotive control
Giulia Romano et al.
NEUROBIOLOGY OF DISEASE (2014)
Antisense Proline-Arginine RAN Dipeptides Linked to C9ORF72-ALS/FTD Form Toxic Nuclear Aggregates that Initiate In Vitro and In Vivo Neuronal Death
Xinmei Wen et al.
NEURON (2014)
Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations
Nael H. Alami et al.
NEURON (2014)
Lipoic acid – biological activity and therapeutic potential
Anna Gorąca et al.
Pharmacological Reports (2014)
C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins
Sarah Mizielinska et al.
SCIENCE (2014)
An ALS-associated mutation in the FUS 3′-UTR disrupts a microRNA-FUS regulatory circuitry
Stefano Dini Modigliani et al.
NATURE COMMUNICATIONS (2014)
HDAC6 Is a Bruchpilot Deacetylase that Facilitates Neurotransmitter Release
Katarzyna Miskiewicz et al.
CELL REPORTS (2014)
piRNA clusters and open chromatin structure
Soichiro Yamanaka et al.
MOBILE DNA (2014)
Bidirectional transcripts of the expanded C9orf72 hexanucleotide repeat are translated into aggregating dipeptide repeat proteins
Kohji Mori et al.
ACTA NEUROPATHOLOGICA (2013)
Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS
Tania F. Gendron et al.
ACTA NEUROPATHOLOGICA (2013)
Reduced C9orf72 gene expression in c9FTD/ALS is caused by histone trimethylation, an epigenetic event detectable in blood
Veronique V. Belzil et al.
ACTA NEUROPATHOLOGICA (2013)
Loss of Function of C9orf72 Causes Motor Deficits in a Zebrafish Model of Amyotrophic Lateral Sclerosis
Sorana Ciura et al.
ANNALS OF NEUROLOGY (2013)
Weight loss, dysphagia and supplement intake in patients with amyotrophic lateral sclerosis (ALS): impact on quality of life and therapeutic options
Sonja Koerner et al.
BMC NEUROLOGY (2013)
Muscleblind, BSF and TBPH are mislocalized in the muscle sarcomere of a Drosophila myotonic dystrophy model
Beatriz Llamusi et al.
DISEASE MODELS & MECHANISMS (2013)
Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis
Patricia S. Estes et al.
DISEASE MODELS & MECHANISMS (2013)
PABPN1: molecular function and muscle disease
Ayan Banerjee et al.
FEBS JOURNAL (2013)
Piwi induces piRNA-guided transcriptional silencing and establishment of a repressive chromatin state
Adrien Le Thomas et al.
GENES & DEVELOPMENT (2013)
Protein disulfide isomerase in ALS mouse glia links protein misfolding with NADPH oxidase-catalyzed superoxide production
Merja Jaronen et al.
HUMAN MOLECULAR GENETICS (2013)
The FTD/ALS-associated RNA-binding protein TDP-43 regulates the robustness of neuronal specification through microRNA-9a in Drosophila
Zhaodong Li et al.
HUMAN MOLECULAR GENETICS (2013)
RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations
J. Gavin Daigle et al.
HUMAN MOLECULAR GENETICS (2013)
Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes
Danielle C. Diaper et al.
HUMAN MOLECULAR GENETICS (2013)
RNA binding mediates neurotoxicity in the transgenic Drosophila model of TDP-43 proteinopathy
Ryoko Ihara et al.
HUMAN MOLECULAR GENETICS (2013)
Drosophila TDP-43 dysfunction in glia and muscle cells cause cytological and behavioural phenotypes that characterize ALS and FTLD
Danielle C. Diaper et al.
HUMAN MOLECULAR GENETICS (2013)
Mutations in the 3′ untranslated region of FUS causing FUS overexpression are associated with amyotrophic lateral sclerosis
Mario Sabatelli et al.
HUMAN MOLECULAR GENETICS (2013)
Stress granules as crucibles of ALS pathogenesis
Yun R. Li et al.
JOURNAL OF CELL BIOLOGY (2013)
Immunodetection of Disease-Associated Conformers of Mutant Cu/Zn Superoxide Dismutase 1 Selectively Expressed in Degenerating Neurons in Amyotrophic Lateral Sclerosis
Javier Sabado et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2013)
Defects in Synapse Structure and Function Precede Motor Neuron Degeneration in Drosophila Models of FUS-Related ALS
Mohammad Shahidullah et al.
JOURNAL OF NEUROSCIENCE (2013)
Oligodendrocyte-Specific Activation of PERK Signaling Protects Mice against Experimental Autoimmune Encephalomyelitis
Wensheng Lin et al.
JOURNAL OF NEUROSCIENCE (2013)
Cognitive changes predict functional decline in ALS A population-based longitudinal study
Marwa Elamin et al.
NEUROLOGY (2013)
Identification of Genetic Modifiers of TDP-43 Neurotoxicity in Drosophila
Lihong Zhan et al.
PLOS ONE (2013)
Deletion of C9ORF72 Results in Motor Neuron Degeneration and Stress Sensitivity in C-elegans
Martine Therrien et al.
PLOS ONE (2013)
Expanded GGGGCC repeat RNA associated with amyotrophic lateral sclerosis and frontotemporal dementia causes neurodegeneration
Zihui Xu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Transposition-Driven Genomic Heterogeneity in the Drosophila Brain
Paola N. Perrat et al.
SCIENCE (2013)
The C9orf72 GGGGCC Repeat Is Translated into Aggregating Dipeptide-Repeat Proteins in FTLD/ALS
Kohji Mori et al.
SCIENCE (2013)
TDP-43 Loss-of-Function Causes Neuronal Loss Due to Defective Steroid Receptor-Mediated Gene Program Switching in Drosophila
Lies Vanden Broeck et al.
CELL REPORTS (2013)
RNA Seeds Higher-Order Assembly of FUS Protein
Jacob C. Schwartz et al.
CELL REPORTS (2013)
ALS-Associated FUS Mutations Result in Compromised FUS Alternative Splicing and Autoregulation
Yueqin Zhou et al.
PLOS GENETICS (2013)
Misfolded SOD1 and ALS: Zeroing in on mitochondria
Sarah Pickles et al.
AMYOTROPHIC LATERAL SCLEROSIS (2012)
Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels
Masato Kato et al.
CELL (2012)
Cell-free Formation of RNA Granules: Bound RNAs Identify Features and Components of Cellular Assemblies
Tina W. Han et al.
CELL (2012)
Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS
Dorothee Dormann et al.
EMBO JOURNAL (2012)
Evolutionarily conserved protein arginine methyltransferases in non-mammalian animal systems
Yi-Chun Wang et al.
FEBS JOURNAL (2012)
High-content RNAi screening identifies the Type 1 inositol triphosphate receptor as a modifier of TDP-43 localization and neurotoxicity
Sang Hwa Kim et al.
HUMAN MOLECULAR GENETICS (2012)
Cellular Model of TAR DNA-binding Protein 43 (TDP-43) Aggregation Based on Its C-terminal Gln/Asn-rich Region
Mauricio Budini et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The syndrome of cognitive impairment in amyotrophic lateral sclerosis: a population-based study
Julie Phukan et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2012)
Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study
Elisa Majounie et al.
LANCET NEUROLOGY (2012)
Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS
Ruohan Xia et al.
MOLECULAR NEURODEGENERATION (2012)
Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system
Hemmo Meyer et al.
NATURE CELL BIOLOGY (2012)
Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs
Clotilde Lagier-Tourenne et al.
NATURE NEUROSCIENCE (2012)
Accumulation of insoluble forms of FUS protein correlates with toxicity in Drosophila
Laetitia Miguel et al.
NEUROBIOLOGY OF AGING (2012)
The Aggregation and Neurotoxicity of TDP-43 and Its ALS-Associated 25 kDa Fragment Are Differentially Affected by Molecular Chaperones in Drosophila
Jenna M. Gregory et al.
PLOS ONE (2012)
Knockdown of the Drosophila Fused in Sarcoma (FUS) Homologue Causes Deficient Locomotive Behavior and Shortening of Motoneuron Terminal Branches
Hiroshi Sasayama et al.
PLOS ONE (2012)
Ataxin-2-Like Is a Regulator of Stress Granules and Processing Bodies
Christian Kaehler et al.
PLOS ONE (2012)
Activation of the unfolded protein response enhances motor recovery after spinal cord injury
V. Valenzuela et al.
CELL DEATH & DISEASE (2012)
Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain
Boris Rogelj et al.
SCIENTIFIC REPORTS (2012)
Comparison of Parallel High-Throughput RNA Sequencing Between Knockout of TDP-43 and Its Overexpression Reveals Primarily Nonreciprocal and Nonoverlapping Gene Expression Changes in the Central Nervous System of Drosophila
Dennis J. Hazelett et al.
G3-GENES GENOMES GENETICS (2012)
Nuclear Transport Impairment of Amyotrophic Lateral Sclerosis-Linked Mutations in FUS/TLS
Daisuke Ito et al.
ANNALS OF NEUROLOGY (2011)
Understanding the role of TDP-43 and FUS/TLS in ALS and beyond
Sandrine Da Cruz et al.
CURRENT OPINION IN NEUROBIOLOGY (2011)
A Drosophila model of FUS-related neurodegeneration reveals genetic interaction between FUS and TDP-43
Nicholas A. Lanson et al.
HUMAN MOLECULAR GENETICS (2011)
Wild-type and A315T mutant TDP-43 exert differential neurotoxicity in a Drosophila model of ALS
Patricia S. Estes et al.
HUMAN MOLECULAR GENETICS (2011)
The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span
Ji-Wu Wang et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Mechanisms of mitophagy
Richard J. Youle et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)
Both cytoplasmic and nuclear accumulations of the protein are neurotoxic in Drosophila models of TDP-43 proteinopathies
Laetitia Miguel et al.
NEUROBIOLOGY OF DISEASE (2011)
Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
Mariely DeJesus-Hernandez et al.
NEURON (2011)
A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
Alan E. Renton et al.
NEURON (2011)
The chromodomains of CHD1 are critical for enzymatic activity but less important for chromatin localization
Stefano Morettini et al.
NUCLEIC ACIDS RESEARCH (2011)
Intracellular localization and splicing regulation of FUS/TLS are variably affected by amyotrophic lateral sclerosis-linked mutations
Yoshihiro Kino et al.
NUCLEIC ACIDS RESEARCH (2011)
THE UNFOLDED PROTEIN RESPONSE: INTEGRATING STRESS SIGNALS THROUGH THE STRESS SENSOR IRE1α
Claudio Hetz et al.
PHYSIOLOGICAL REVIEWS (2011)
Neuronal Function and Dysfunction of Drosophila dTDP
Meng-Jau Lin et al.
PLOS ONE (2011)
A yeast functional screen predicts new candidate ALS disease genes
Julien Couthouis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
Peter Walter et al.
SCIENCE (2011)
Biogenesis and function of nuclear bodies
Yuntao S. Mao et al.
TRENDS IN GENETICS (2011)
Molecular Determinants and Genetic Modifiers of Aggregation and Toxicity for the ALS Disease Protein FUS/TLS
Zhihui Sun et al.
PLOS BIOLOGY (2011)
The ISWI Chromatin Remodeler Organizes the hsrω ncRNA-Containing Omega Speckle Nuclear Compartments
Maria C. Onorati et al.
PLOS GENETICS (2011)
FUS and TARDBP but Not SOD1 Interact in Genetic Models of Amyotrophic Lateral Sclerosis
Edor Kabashi et al.
PLOS GENETICS (2011)
FUS Transgenic Rats Develop the Phenotypes of Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration
Cao Huang et al.
PLOS GENETICS (2011)
Expression of human FUS protein in Drosophila leads to progressive neurodegeneration
Yanbo Chen et al.
PROTEIN & CELL (2011)
Impaired glucose tolerance in patients with amyotrophic lateral sclerosis
Pierre-Francois Pradat et al.
AMYOTROPHIC LATERAL SCLEROSIS (2010)
Nuclear functions of the HMG proteins
Raymond Reeves
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2010)
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6
Fabienne C. Fiesel et al.
EMBO JOURNAL (2010)
ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import
Dorothee Dormann et al.
EMBO JOURNAL (2010)
Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules
Daryl A. Bosco et al.
HUMAN MOLECULAR GENETICS (2010)
Ubiquilin Modifies TDP-43 Toxicity in a Drosophila Model of Amyotrophic Lateral Sclerosis (ALS)
Keith A. Hanson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Amyotrophic Lateral Sclerosis-associated Proteins TDP-43 and FUS/TLS Function in a Common Biochemical Complex to Co-regulate HDAC6 mRNA
Sang Hwa Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Mutations of FUS gene in sporadic amyotrophic lateral sclerosis
Lucia Corrado et al.
JOURNAL OF MEDICAL GENETICS (2010)
TDP-43 Mediates Degeneration in a Novel Drosophila Model of Disease Caused by Mutations in VCP/p97
Gillian P. Ritson et al.
JOURNAL OF NEUROSCIENCE (2010)
TLS Inhibits RNA Polymerase III Transcription
Adelene Y. Tan et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
Gymnastics of Molecular Chaperones
Matthias P. Mayer
MOLECULAR CELL (2010)
Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS
Andrew C. Elden et al.
NATURE (2010)
Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS
Jane O. Johnson et al.
NEURON (2010)
TDP-43-Mediated Neuron Loss In Vivo Requires RNA-Binding Activity
Aaron Voigt et al.
PLOS ONE (2010)
A Drosophila model for TDP-43 proteinopathy
Yan Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The multiple roles of TDP-43 in pre-mRNA processing and gene expression regulation
Emanuele Buratti et al.
RNA BIOLOGY (2010)
Rethinking ALS: The FUS about TDP-43
Clotilde Lagier-Tourenne et al.
CELL (2009)
Regulation of Organ Size: Insights From the Drosophila Hippo Signaling Pathway
Madhuri Kango-Singh et al.
DEVELOPMENTAL DYNAMICS (2009)
Depletion of TDP-43 affects Drosophila motoneurons terminal synapsis and locomotive behavior
Fabian Feiguin et al.
FEBS LETTERS (2009)
Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond
Hristelina Ilieva et al.
JOURNAL OF CELL BIOLOGY (2009)
Hypermetabolism in ALS patients: an early and persistent phenomenon
C. Bouteloup et al.
JOURNAL OF NEUROLOGY (2009)
Functional mapping of the interaction between TDP-43 and hnRNP A2 in vivo
Andrea D'Ambrogio et al.
NUCLEIC ACIDS RESEARCH (2009)
Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6
Caroline Vance et al.
SCIENCE (2009)
Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis
T. J. Kwiatkowski et al.
SCIENCE (2009)
Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branching
Yubing Lu et al.
MOLECULAR BRAIN (2009)
Sporadic amyotrophic lateral sclerosis: two pathological patterns shown by analysis of distribution of TDP-43-immunoreactive neuronal and glial cytoplasmic inclusions
Yasushi Nishihira et al.
ACTA NEUROPATHOLOGICA (2008)
Enhanced Integrated Stress Response Promotes Myelinating Oligodendrocyte Survival in Response to Interferon-γ
Wensheng Lin et al.
AMERICAN JOURNAL OF PATHOLOGY (2008)
TDP-43 mutation in familial amyotrophic lateral sclerosis
Akio Yokoseki et al.
ANNALS OF NEUROLOGY (2008)
TDP-43 A315T mutation in familial motor neuron disease
Michael A. Gitcho et al.
ANNALS OF NEUROLOGY (2008)
Mechanisms of Cdc48/VCP-mediated cell death - from yeast apoptosis to human disease
Ralf J. Braun et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2008)
The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response
Mattias K. Andersson et al.
BMC CELL BIOLOGY (2008)
Abnormal phosphorylation of ser409/410 of TDP-43 in FTLD-U and ALS
Yuki Inukai et al.
FEBS LETTERS (2008)
A Drosophila model for amyotrophic lateral sclerosis reveals motor neuron damage by human SOD1
Melanie R. Watson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology:: a genetic and histopathological analysis
Vivianna M. Van Deerlin et al.
LANCET NEUROLOGY (2008)
TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
Edor Kabashi et al.
NATURE GENETICS (2008)
Dyslipidemia is a protective factor in amyotrophic lateral sclerosis
L. Dupuis et al.
NEUROLOGY (2008)
Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells
Megha Ghildiyal et al.
SCIENCE (2008)
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
Jemeen Sreedharan et al.
SCIENCE (2008)
Novel Mutations in TARDBP(TDP-43) in Patients with Familial Amyotrophic Lateral Sclerosis
Nicola J. Rutherford et al.
PLOS GENETICS (2008)
TDP-43-immunoreactive neuronal and glial inclusions in the neostriatum in amyotrophic lateral sclerosis with and without dementia
Haixin Zhang et al.
ACTA NEUROPATHOLOGICA (2008)
Mitochondrial alterations in dorsal root ganglion cells in sporadic amyotrophic lateral sclerosis
Shoichi Sasaki et al.
ACTA NEUROPATHOLOGICA (2007)
Exogenous delivery of heat shock protein 70 increases lifespan in a mouse model of amyotrophic lateral sclerosis
David J. Gifondorwa et al.
JOURNAL OF NEUROSCIENCE (2007)
Wild-type superoxide dismutase acquires binding and toxic properties of ALS-linked mutant forms through oxidation
Samer Abou Ezzi et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Stress-induced retrotranslocation of clusterin/ApoJ into the cytosol
Philippe Nizard et al.
TRAFFIC (2007)
TDP-43-positive white matter pathology in frontotemporal lobar degeneration with ubiquitin-positive inclusions
Manuela Neumann et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2007)
HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates
Cyril Boyault et al.
GENES & DEVELOPMENT (2007)
Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules
Ute Nonhoff et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Tetsuaki Arai et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Human sat III and Drosophila hsrω transcripts:: a common paradigm for regulation of nuclear RNA processing in stressed cells
Caroline Jolly et al.
NUCLEIC ACIDS RESEARCH (2006)
MicroRNA-9a ensures the precise specification of sensory organ precursors in Drosophila
Yan Li et al.
GENES & DEVELOPMENT (2006)
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Manuela Neumann et al.
SCIENCE (2006)
Drosophila in the study of neurodegenerative disease
J. Lawrence Marsh et al.
NEURON (2006)
Rules for nuclear localization sequence recognition by karyopherinβ2
Brittany J. Lee et al.
CELL (2006)
Bruchpilot promotes active zone assembly, Ca2+ channel clustering, and vesicle release
RJ Kittel et al.
SCIENCE (2006)
Structural properties and neuronal toxicity of amyotrophic lateral sclerosis-associated Cu/Zn superoxide dismutase 1 aggregates
G Matsumoto et al.
JOURNAL OF CELL BIOLOGY (2005)
Antioxidant activity of gamma-oryzanol: Mechanism of action and its effect on oxidative stability of pharmaceutical oils
C Juliano et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2005)
Human, Drosophila, and C-elegans TDP43:: Nucleic acid binding properties and splicing regulatory function
YM Ayala et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Translational control in stress and apoptosis
M Holcik et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
Characterization of the Drosophila protein arginine methyltransferases DART1 and DART4
MC Boulanger et al.
BIOCHEMICAL JOURNAL (2004)
Kinesin transports RNA: Isolation and characterization of an RNA-transporting granule
Y Kanai et al.
NEURON (2004)
Structural diversity and functional implications of the eukaryotic TDP gene family
HY Wang et al.
GENOMICS (2004)
Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis show enhanced formation of aggregates in vitro
PB Stathopulos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Phenotypic effects of familial amyotrophic lateral sclerosis mutant Sod alleles in transgenic Drosophila
RJ Mockett et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site
J Wang et al.
NEUROBIOLOGY OF DISEASE (2002)
Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease
MM Lino et al.
JOURNAL OF NEUROSCIENCE (2002)
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
H Nishitoh et al.
GENES & DEVELOPMENT (2002)
Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules
N Kedersha et al.
MOLECULAR BIOLOGY OF THE CELL (2002)
High molecular weight complexes of mutant superoxide dismutase 1: Age-dependent and tissue-specific accumulation
J Wang et al.
NEUROBIOLOGY OF DISEASE (2002)
From Charcot to Lou Gehrig: Deciphering selective motor neuron death in ALS
DW Cleveland et al.
NATURE REVIEWS NEUROSCIENCE (2001)
A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster
LT Reiter et al.
GENOME RESEARCH (2001)
Medical progress: Amyotrophic lateral sclerosis.
LP Rowland et al.
NEW ENGLAND JOURNAL OF MEDICINE (2001)
Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment
A Pramatarova et al.
JOURNAL OF NEUROSCIENCE (2001)
Mutant Cu/Zn-superoxide dismutase proteins have altered solubility and interact with heat shock/stress proteins in models of amyotrophic lateral sclerosis
GA Shinder et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Involvement of the pro-oncoprotein TLS (translocated in liposarcoma) in nuclear factor-κB p65-mediated transcription as a coactivator
H Uranishi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation
MR Brouns et al.
NATURE CELL BIOLOGY (2001)
Formation of high molecular weight complexes of mutant Cu,Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis
JA Johnston et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
The genome sequence of Drosophila melanogaster
MD Adams et al.
SCIENCE (2000)
A whole-genome assembly of Drosophila
EW Myers et al.
SCIENCE (2000)
Perinucleolar structures
S Huang
JOURNAL OF STRUCTURAL BIOLOGY (2000)
Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration
YH Gong et al.
JOURNAL OF NEUROSCIENCE (2000)