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Efficacy and Safety of A Liposome-Based Vaccine against Protein Tau, Assessed in Tau.P301L Mice That Model Tauopathy
Clara Theunis et al.
PLOS ONE (2013)
Seizures and Epileptiform Activity in the Early Stages of Alzheimer Disease
Keith A. Vossel et al.
JAMA NEUROLOGY (2013)
Epilepsy: neuroinflammation, neurodegeneration, and APOE genotype
Orwa Aboud et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2013)
Inhibitory Interneuron Deficit Links Altered Network Activity and Cognitive Dysfunction in Alzheimer Model
Laure Verret et al.
CELL (2012)
Synaptic and Extrasynaptic NMDA Receptors Are Gated by Different Endogenous Coagonists
Thomas Papouin et al.
CELL (2012)
PP2A and Alzheimer Disease
L. Torrent et al.
CURRENT ALZHEIMER RESEARCH (2012)
Insulin: An Emerging Treatment for Alzheimer's Disease Dementia?
Jill K. Morris et al.
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2012)
GABA Attenuates Amyloid Toxicity by Downregulating its Endocytosis and Improves Cognitive Impairment
Xiaqin Sun et al.
JOURNAL OF ALZHEIMERS DISEASE (2012)
Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation
Scott A. Yuzwa et al.
NATURE CHEMICAL BIOLOGY (2012)
Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
Charles A. Dinarello et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
Perampanel-new promise for refractory epilepsy?
Wolfgang Loescher et al.
NATURE REVIEWS NEUROLOGY (2012)
Reduction of Hippocampal Hyperactivity Improves Cognition in Amnestic Mild Cognitive Impairment
Arnold Bakker et al.
NEURON (2012)
Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model
Pascal E. Sanchez et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Critical role of soluble amyloid-β for early hippocampal hyperactivity in a mouse model of Alzheimer's disease
Marc Aurel Busche et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Seizures in Alzheimer Disease: Clinical and Epidemiological Data
Dionysios Pandis et al.
EPILEPSY CURRENTS (2012)
Aspirin, steroidal and non-steroidal anti-inflammatory drugs for the treatment of Alzheimer's disease
Darin Jaturapatporn et al.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2012)
The potential protective effect of tramiprosate (homotaurine) against Alzheimer's disease: a review
Carlo Caltagirone et al.
AGING CLINICAL AND EXPERIMENTAL RESEARCH (2012)
Chronic Divalproex Sodium to Attenuate Agitation and Clinical Progression of Alzheimer Disease
Pierre N. Tariot et al.
ARCHIVES OF GENERAL PSYCHIATRY (2011)
Tramiprosate in mild-to-moderate Alzheimer's disease - a randomized, double-blind, placebo-controlled, multi-centre study (the Alphase Study)
Paul S. Aisen et al.
ARCHIVES OF MEDICAL SCIENCE (2011)
Amyloid β peptide oligomers directly activate NMDA receptors
Laura Texido et al.
CELL CALCIUM (2011)
Spontaneous epileptiform discharges in a mouse model of Alzheimer's disease are suppressed by antiepileptic drugs that block sodium channels
Sofya Ziyatdinova et al.
EPILEPSY RESEARCH (2011)
Long-Term Treatment with Lithium Alleviates Memory Deficits and Reduces Amyloid-beta Production in an Aged Alzheimer's Disease Transgenic Mouse Model
Xin Zhang et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Transcranial magnetic stimulation in Alzheimer's disease: a neurophysiological marker of cortical hyperexcitability
Giovanni Pennisi et al.
JOURNAL OF NEURAL TRANSMISSION (2011)
Amyloid-β/Fyn-Induced Synaptic, Network, and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer's Disease
Erik D. Roberson et al.
JOURNAL OF NEUROSCIENCE (2011)
Hippocampal Hyperactivation Associated with Cortical Thinning in Alzheimer's Disease Signature Regions in Non-Demented Elderly Adults
Deepti Putcha et al.
JOURNAL OF NEUROSCIENCE (2011)
Lysophosphatidic acid induces neurite retraction in differentiated neuroblastoma cells via GSK-3β activation
Yuanjie Sun et al.
MOLECULES AND CELLS (2011)
Neuronal activity regulates the regional vulnerability to amyloid-β deposition
Adam W. Bero et al.
NATURE NEUROSCIENCE (2011)
The role of inflammation in epilepsy
Annamaria Vezzani et al.
NATURE REVIEWS NEUROLOGY (2011)
Linking lipids to Alzheimer's disease: cholesterol and beyond
Gilbert Di Paolo et al.
NATURE REVIEWS NEUROSCIENCE (2011)
Protection against Aβ-mediated rapid disruption of synaptic plasticity and memory by memantine
Igor Klyubin et al.
NEUROBIOLOGY OF AGING (2011)
Chronic divalproex sodium use and brain atrophy in Alzheimer disease
A. S. Fleisher et al.
NEUROLOGY (2011)
Levetiracetam in the treatment of epilepsy
Bassel Abou-Khalil
Neuropsychiatric Disease and Treatment (2011)
Masitinib as an adjunct therapy for mild-to-moderate Alzheimer's disease: a randomised, placebo-controlled phase 2 trial
Francois Piette et al.
ALZHEIMERS RESEARCH & THERAPY (2011)
GSK-3 inhibitors: preclinical and clinical focus on CNS
Hagit Eldar-Finkelman et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2011)
Levetiracetam: A Practical Option for Seizure Management in Elderly Patients With Cognitive Impairment
Carol F. Lippa et al.
AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS (2010)
Hippocampal Hyperactivation in Presymptomatic Familial Alzheimer's Disease
Yakeel T. Quiroz et al.
ANNALS OF NEUROLOGY (2010)
Heterogeneous neuronal firing patterns during interictal epileptiform discharges in the human cortex
Corey J. Keller et al.
BRAIN (2010)
Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models
Lars M. Ittner et al.
CELL (2010)
Levetiracetam, lamotrigine, and phenobarbital in patients with epileptic seizures and Alzheimer's disease
Eduardo Cumbo et al.
EPILEPSY & BEHAVIOR (2010)
Functional Connectivity in Mild Cognitive Impairment During a Memory Task: Implications for the Disconnection Hypothesis
Ricardo Bajo et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Apolipoprotein E4 Causes Age- and Tau-Dependent Impairment of GABAergic Interneurons, Leading to Learning and Memory Deficits in Mice
Yaisa Andrews-Zwilling et al.
JOURNAL OF NEUROSCIENCE (2010)
Amyloid β Induces the Morphological Neurodegenerative Triad of Spine Loss, Dendritic Simplification, and Neuritic Dystrophies through Calcineurin Activation
Hai-Yan Wu et al.
JOURNAL OF NEUROSCIENCE (2010)
BACE1-/- mice exhibit seizure activity that does not correlate with sodium channel level or axonal localization
Brian D. Hitt et al.
MOLECULAR NEURODEGENERATION (2010)
Amyloid-β-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks
Jorge J. Palop et al.
NATURE NEUROSCIENCE (2010)
Tau-knockout mice show reduced GSK3-induced hippocampal degeneration and learning deficits
Elena Gomez de Barreda et al.
NEUROBIOLOGY OF DISEASE (2010)
Exploratory, anxiety and spatial memory impairments are dissociated in mice lacking the LPA1 receptor
Estela Castilla-Ortega et al.
NEUROBIOLOGY OF LEARNING AND MEMORY (2010)
High-resolution structural and functional MRI of hippocampal CA3 and dentate gyrus in patients with amnestic Mild Cognitive Impairment
Michael A. Yassa et al.
NEUROIMAGE (2010)
Cognitive effects of pregabalin in healthy volunteers A double-blind, placebo-controlled trial
Martin Salinsky et al.
NEUROLOGY (2010)
Treatment Strategies Targeting Excess Hippocampal Activity Benefit Aged Rats with Cognitive Impairment
Ming Teng Koh et al.
NEUROPSYCHOPHARMACOLOGY (2010)
Ethosuximide, Valproic Acid, and Lamotrigine in Childhood Absence Epilepsy.
Tracy A. Glauser et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Epilepsy and Cognitive Impairments in Alzheimer Disease
Jorge J. Palop et al.
ARCHIVES OF NEUROLOGY (2009)
Antiepileptic Drug-Induced Cognitive Adverse Effects Potential Mechanisms and Contributing Factors
Marco Mula et al.
CNS DRUGS (2009)
Temporal cortex direct current stimulation enhances performance on a visual recognition memory task in Alzheimer disease
P. S. Boggio et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2009)
Glycine Site of NMDA Receptor Serves as a Spatiotemporal Detector of Synaptic Activity Patterns
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JOURNAL OF NEUROPHYSIOLOGY (2009)
A Novel Nicotinic Acetylcholine Receptor Subtype in Basal Forebrain Cholinergic Neurons with High Sensitivity to Amyloid Peptides
Qiang Liu et al.
JOURNAL OF NEUROSCIENCE (2009)
Amyloid β-Induced Neuronal Hyperexcitability Triggers Progressive Epilepsy
Rimante Minkeviciene et al.
JOURNAL OF NEUROSCIENCE (2009)
Amyloid-β as a positive endogenous regulator of release probability at hippocampal synapses
Efrat Abramov et al.
NATURE NEUROSCIENCE (2009)
A novel GSK-3 beta inhibitor reduces Alzheimer's pathology and rescues neuronal loss in vivo
L. Sereno et al.
NEUROBIOLOGY OF DISEASE (2009)
Oligomeric amyloid β associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques
Robert M. Koffie et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Diminished perisomatic GABAergic terminals on cortical neurons adjacent to amyloid plaques
Virginia Garcia-Marin et al.
FRONTIERS IN NEUROANATOMY (2009)
Glycogen synthase kinase-3β, or a link between amyloid and tau pathology?
D. Muyllaert et al.
GENES BRAIN AND BEHAVIOR (2008)
Valproic acid inhibits Aβ production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse models
Hong Qing et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease
Rene O. Sanchez-Mejia et al.
NATURE NEUROSCIENCE (2008)
Loss of VGLUT1 and VGLUT2 in the prefrontal cortex is correlated with cognitive decline in Alzheimer disease
Alireza Kashani et al.
NEUROBIOLOGY OF AGING (2008)
Transcranial direct current stimulation improves recognition memory in Alzheimer disease
R. Ferrucci et al.
NEUROLOGY (2008)
Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease
Marc Aurel Busche et al.
SCIENCE (2008)
E/I balance and GABAA receptor plasticity
Jean-Marc Fritschy
Frontiers in Molecular Neuroscience (2008)
The GSK3 hypothesis of Alzheimer's disease
Claudie Hooper et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Intranasal insulin improves cognition and modulates β-amyloid in early AD
M. A. Reger et al.
NEUROLOGY (2008)
Increased fMRI responses during encoding in mild cognitive impairment
Anne Hämäläinen et al.
NEUROBIOLOGY OF AGING (2007)
Valsartan lowers brain β-amyloid protein levels and improves spatial learning in a mouse model of Alzheimer disease
Jun Wang et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease
Jorge J. Palop et al.
NEURON (2007)
Pathological tau tangles localize to focal cortical dysplasia in older patients
Arjune Sen et al.
EPILEPSIA (2007)
Reducing endogenous tau ameliorates amyloid β-induced deficits in an Alzheimer's disease mouse model
Erik D. Roberson et al.
SCIENCE (2007)
Targeting soluble Aβ peptide with Tramiprosate for the treatment of brain amyloidosis
Francine Gervais et al.
NEUROBIOLOGY OF AGING (2007)
UP inhibits LTD in the hippocampus via regulation of GSK3β
Stephane Peineau et al.
NEURON (2007)
Neuroprotective effects of regulators of the glycogen synthase kinase-3β signaling pathway in a transgenic model of Alzheimer's disease are associated with reduced amyloid precursor protein phosphorylation
Edward Rockenstein et al.
JOURNAL OF NEUROSCIENCE (2007)
Neurocognitive aging: prior memories hinder new hippocampal encoding
Iain A. Wilson et al.
TRENDS IN NEUROSCIENCES (2006)
Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: An independent component analysis
Kim A. Celone et al.
JOURNAL OF NEUROSCIENCE (2006)
High-frequency intracerebral EEG activity (100-500 Hz) following interictal spikes
Elena Urrestarazu et al.
EPILEPSIA (2006)
Magnetoencephalographic evaluation of resting-state functional connectivity in Alzheimer's disease
C. J. Stam et al.
NEUROIMAGE (2006)
Involvement of I2PP2A in the abnormal hyperphosphorylation of tau and its reversal by Memantine
Muhammad Omar Chohan et al.
FEBS LETTERS (2006)
Tau phosphorylation and aggregation in Alzheimer's disease pathology
J Avila
FEBS LETTERS (2006)
Familial risk for Alzheimer's disease alters fMRI activation patterns
SS Bassett et al.
BRAIN (2006)
Incidence and predictors of seizures in patients with Alzheimer's disease
JC Amatniek et al.
EPILEPSIA (2006)
Lipopolysaccharide-induced microglial activation induces learning and memory deficits without neuronal cell death in rats
S Tanaka et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2006)
Safety of rTMS to non-motor cortical areas in healthy participants and patients
K Machii et al.
CLINICAL NEUROPHYSIOLOGY (2006)
Medial temporal lobe neuromagnetic hypoactivation and risk for developing cognitive decline in elderly population: A 2-year follow-up study
F Maestu et al.
NEUROBIOLOGY OF AGING (2006)
Chronic lithium treatment decreases tau lesions by promoting ubiquitination in a mouse model of tauopathies
H Nakashima et al.
ACTA NEUROPATHOLOGICA (2005)
Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD
BC Dickerson et al.
NEUROLOGY (2005)
Regulation of NMDA receptor trafficking by amyloid-β
EM Snyder et al.
NATURE NEUROSCIENCE (2005)
fMRI evidence of compensatory mechanisms in older adults at genetic risk for Alzheimer disease
MW Bondi et al.
NEUROLOGY (2005)
Theta burst stimulation of the human motor cortex
YZ Huang et al.
NEURON (2005)
EEG dynamics in patients with Alzheimer's disease
JS Jeong
CLINICAL NEUROPHYSIOLOGY (2004)
Receptor trafficking and synaptic plasticity
GL Collingridge et al.
NATURE REVIEWS NEUROSCIENCE (2004)
SGS742:: the first GABAB receptor antagonist in clinical trials
W Froestl et al.
BIOCHEMICAL PHARMACOLOGY (2004)
Learning modulation by endogenous hippocampal IL-1: Blockade of endogenous IL-1 facilitates memory formation
AM Depino et al.
HIPPOCAMPUS (2004)
The Mood-Stabilizing Agent Valproate Inhibits the Activity of Glycogen Synthase Kinase-3
Guang Chen et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Sedation caused by primidone may exacerbate dementia
HJ Koch et al.
EPILEPSY & BEHAVIOR (2003)
Alzheimer's disease as a disconnection syndrome?
X Delbeuck et al.
NEUROPSYCHOLOGY REVIEW (2003)
GSK-3α regulates production of Alzheimer's disease amyloid-β peptides
CJ Phiel et al.
NATURE (2003)
Aβ toxicity in Alzheimer's disease:: globular oligomers (ADDLs) as new vaccine and drug targets
WL Klein
NEUROCHEMISTRY INTERNATIONAL (2002)
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
DM Walsh et al.
NATURE (2002)
Interleukin-1, neuroinflammation, and Alzheimer's disease
RE Mrak et al.
NEUROBIOLOGY OF AGING (2001)
Site-directed antisense oligonucleotide decreases the expression of amyloid precursor protein and reverses deficits in learning and memory in aged SAMP8 mice
VB Kumar et al.
PEPTIDES (2000)
Interleukin-1 and the immunogenetics of Alzheimer disease
RE Mrak et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2000)
D-β-hydroxybutyrate protects neurons in models of Alzheimer's and Parkinson's disease
Y Kashiwaya et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)