4.7 Review

Targeting CTLA-4 in cancer: Is it the ideal companion for PD-1 blockade immunotherapy combinations?

Related references

Note: Only part of the references are listed.
Article Medicine, General & Internal

Immune-related adverse events of checkpoint inhibitors

Manuel Ramos-Casals et al.

NATURE REVIEWS DISEASE PRIMERS (2020)

Review Oncology

Immunotherapy and targeted therapy combinations in metastatic breast cancer

Francisco J. Esteva et al.

LANCET ONCOLOGY (2019)

Article Oncology

Radiotherapy enhances responses of lung cancer to CTLA-4 blockade

Anna Wilkins et al.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)

Review Oncology

Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance

Filipe Martins et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2019)

Article Oncology

CTLA-4 antibody ipilimumab negatively affects CD4+ T-cell responses in vitro

Sandra Rosskopf et al.

CANCER IMMUNOLOGY IMMUNOTHERAPY (2019)

Review Oncology

Immune-Related Adverse Events: A Case-Based Approach

Caoilfhionn Connolly et al.

FRONTIERS IN ONCOLOGY (2019)

Article Medicine, General & Internal

Nivolumab plus Ipilimumab in Advanced Non-Small-Cell Lung Cancer

M. D. Hellmann et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Review Oncology

Targeting PD-1 in cancer: Biological insights with a focus on breast cancer

Cinzia Solinas et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2019)

Review Oncology

Significance of TIM3 expression in cancer: From biology to the clinic

Cinzia Solinas et al.

SEMINARS IN ONCOLOGY (2019)

Review Pharmacology & Pharmacy

Immune mechanisms mediating abscopal effects in radioimmunotherapy

Maria E. Rodriguez-Ruiz et al.

PHARMACOLOGY & THERAPEUTICS (2019)

Review Immunology

Combining Radiotherapy With Anti-angiogenic Therapy and Immunotherapy; A Therapeutic Triad for Cancer?

Ruben S. A. Goedegebuure et al.

FRONTIERS IN IMMUNOLOGY (2019)

Review Oncology

The evolving landscape of biomarkers for checkpoint inhibitor immunotherapy

Jonathan J. Havel et al.

NATURE REVIEWS CANCER (2019)

Review Immunology

Regulation and Function of the PD-L1 Checkpoint

Chong Sun et al.

IMMUNITY (2018)

Article Medicine, General & Internal

Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma

R. J. Motzer et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Medicine, General & Internal

Nivolumab plus Ipilimumab in Lung Cancer with a High Tumor Mutational Burden

M. D. Hellmann et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Review Medicine, General & Internal

Immune-Related Adverse Events Associated with Immune Checkpoint Blockade

Michael A. Postow et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Oncology

Combination of radiotherapy and immune treatment: First clinical data

D. De Ruysscher

CANCER RADIOTHERAPIE (2018)

Review Cell Biology

The hallmarks of successful anticancer immunotherapy

Lorenzo Galluzzi et al.

SCIENCE TRANSLATIONAL MEDICINE (2018)

Review Oncology

Fundamental Mechanisms of Immune Checkpoint Blockade Therapy

Spencer C. Wei et al.

CANCER DISCOVERY (2018)

Review Immunology

Not All Immune Checkpoints Are Created Equal

Annika De Sousa Linhares et al.

FRONTIERS IN IMMUNOLOGY (2018)

Editorial Material Oncology

Nobel committee honors tumor immunologists

Anand Rotte et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018)

Editorial Material Immunology

How Does an Anti-CTLA-4 Antibody Promote Cancer Immunity?

Yang Liu et al.

TRENDS IN IMMUNOLOGY (2018)

Review Immunology

CTLA-4 and PD-1 Control of T-Cell Motility and Migration: Implications for Tumor Immunotherapy

Monika C. Brunner-Weinzierl et al.

FRONTIERS IN IMMUNOLOGY (2018)

Review Hematology

CTLA-4: a moving target in immunotherapy

Behzad Rowshanravan et al.

BLOOD (2018)

Article Multidisciplinary Sciences

T-cell invigoration to tumour burden ratio associated with anti-PD-1 response

Alexander C. Huang et al.

NATURE (2017)

Review Multidisciplinary Sciences

Elements of cancer immunity and the cancer-immune set point

Daniel S. Chen et al.

NATURE (2017)

Article Medicine, General & Internal

Adjuvant Nivolumab versus Ipilimumab in Resected Stage III or IV Melanoma

J. Weber et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Medicine, General & Internal

Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma

J. D. Wolchok et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Review Oncology

Critical features and challenges associated with imaging in patients undergoing cancer immunotherapy

Cinzia Solinas et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2017)

Article Biochemistry & Molecular Biology

Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade

Spencer C. Wei et al.

Article Medicine, Research & Experimental

CXCL13-producing TFH cells link immune suppression and adaptive memory in human breast cancer

Chunyan Gu-Trantien et al.

JCI INSIGHT (2017)

Review Oncology

CTLA-4 and PD-1 Pathways Similarities, Differences, and Implications of Their Inhibition

Elizabeth I. Buchbinder et al.

AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS (2016)

Article Medicine, General & Internal

Prolonged Survival in Stage III Melanoma with Ipilimumab Adjuvant Therapy

A. M. M. Eggermont et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Multidisciplinary Sciences

Clonal expansion of CD8 T cells in the systemic circulation precedes development of ipilimumab-induced toxicities

Sumit K. Subudhi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Editorial Material Oncology

Pseudoprogression and Immune-Related Response in Solid Tumors

Victoria L. Chiou et al.

JOURNAL OF CLINICAL ONCOLOGY (2015)

Letter Medicine, General & Internal

Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

Matias E. Valsecchi

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Multidisciplinary Sciences

Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patients

Emanuela Romano et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Review Multidisciplinary Sciences

The future of immune checkpoint therapy

Padmanee Sharma et al.

SCIENCE (2015)

Review Immunology

Confusing signals: Recent progress in CTLA-4 biology

Lucy S. K. Walker et al.

TRENDS IN IMMUNOLOGY (2015)

Review Immunology

Molecular and cellular insights into T cell exhaustion

E. John Wherry et al.

NATURE REVIEWS IMMUNOLOGY (2015)

Article Medicine, General & Internal

Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma

Alexandra Snyder et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Article Cell Biology

Improved Survival with T Cell Clonotype Stability After Anti-CTLA-4 Treatment in Cancer Patients

Edward Cha et al.

SCIENCE TRANSLATIONAL MEDICINE (2014)

Review Immunology

Metabolic Regulation of T Lymphocytes

Nancie J. MacIver et al.

ANNUAL REVIEW OF IMMUNOLOGY, VOL 31 (2013)

Article Medicine, General & Internal

Immunologic Correlates of the Abscopal Effect in a Patient with Melanoma

Michael A. Postow et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Review Oncology

The blockade of immune checkpoints in cancer immunotherapy

Drew M. Pardoll

NATURE REVIEWS CANCER (2012)

Review Immunology

T cell exhaustion

E. John Wherry

NATURE IMMUNOLOGY (2011)

Review Immunology

The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses

Lucy S. K. Walker et al.

NATURE REVIEWS IMMUNOLOGY (2011)

Review Immunology

The PD-1 pathway in tolerance and autoimmunity

Loise M. Francisco et al.

IMMUNOLOGICAL REVIEWS (2010)

Article Medicine, General & Internal

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

F. Stephen Hodi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Review Immunology

PD-1 and its ligands in tolerance and immunity

Mary E. Keir et al.

ANNUAL REVIEW OF IMMUNOLOGY (2008)

Article Multidisciplinary Sciences

CTLA-4 blockade increases IFNγ-producing CD4+ICOShi cells to shift the ratio of effector to regulatory T cells in cancer patients

Chrysoula I. Liakou et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

CTLA-4 control over Foxp3+ regulatory T cell function

Kajsa Wing et al.

SCIENCE (2008)

Review Immunology

PD-1 and PD-1 ligands: from discovery to clinical application

Taku Okazaki et al.

INTERNATIONAL IMMUNOLOGY (2007)

Article Medicine, Research & Experimental

CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells

Sergio A. Quezada et al.

JOURNAL OF CLINICAL INVESTIGATION (2006)

Review Immunology

Cancer immunoediting: from immunosurveillance to tumor escape

GP Dunn et al.

NATURE IMMUNOLOGY (2002)

Article Immunology

The CD28 signaling pathway regulates glucose metabolism

KA Frauwirth et al.

IMMUNITY (2002)

Article Immunology

PD-L2 is a second ligand for PD-I and inhibits T cell activation

Y Latchman et al.

NATURE IMMUNOLOGY (2001)