4.7 Review

Multifunctional role of fucoidan, sulfated polysaccharides in human health and disease: A journey under the sea in pursuit of potent therapeutic agents

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Effects of a combined fucoidan and traditional Chinese medicine formula on hyperglycaemia and diabetic nephropathy in a type II diabetes mellitus rat model

Yongbo Peng et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Review Biotechnology & Applied Microbiology

Fucoidans: The importance of processing on their anti-tumoral properties

M. D. Torres et al.

ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS (2020)

Article Biochemistry & Molecular Biology

Fucoidan from Ecklonia maxima is a powerful inhibitor of the diabetes-related enzyme, α-glucosidase

Chantal Desiree Daub et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Biochemistry & Molecular Biology

Low molecular weight fucoidan alleviates diabetic nephropathy by binding fibronectin and inhibiting ECM-receptor interaction in human renal mesangial cells

Jing Wang et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Biochemistry & Molecular Biology

Cytotoxic and pharmacokinetic studies of Indian seaweed polysaccharides for formulating raindrop synbiotic candy

M. Ajanth Praveen et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Pharmacology & Pharmacy

Fucoidan Promotes Apoptosis and Inhibits EMT of Breast Cancer Cells

Xinjia He et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2019)

Review Chemistry, Medicinal

Marine natural products as source of new drugs: a patent review (2015-2018)

Pravin Shinde et al.

EXPERT OPINION ON THERAPEUTIC PATENTS (2019)

Article Biochemistry & Molecular Biology

Comparison of structure and in vitro anticancer activity of native and modified fucoidans from Sargassum feldmannii and S. duplicatum

Roza V. Usoltseva et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Article Biochemistry & Molecular Biology

Sargassum fusiforme fucoidan modifies the gut microbiota during alleviation of streptozotocin-induced hyperglycemia in mice

Yang Cheng et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Review Chemistry, Medicinal

Therapies from Fucoidan: New Developments

J. Helen Fitton et al.

MARINE DRUGS (2019)

Article Biochemistry & Molecular Biology

Primary structure and anticoagulant activity of fucoidan from the sea cucumber Holothuria polii

Mohamed Ben Mansour et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Review Cell Biology

Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins

Rumani Singh et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)

Review Biochemistry & Molecular Biology

Marine natural products

Anthony R. Carroll et al.

NATURAL PRODUCT REPORTS (2019)

Article Agriculture, Multidisciplinary

Immune Activation of RAW264.7 Macrophages by Low Molecular Weight Fucoidan Extracted from New Zealand Undaria pinnatifida

Decheng Bi et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2018)

Article Biochemistry & Molecular Biology

Hypoglycemic and hypolipidemic effects of a polysaccharide from flower buds of Lonicera japonica in streptozotocin-induced diabetic rats

Dongying Wang et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2017)

Review Food Science & Technology

Fucoidan as bio-functional molecule: Insights into the anti-inflammatory potential and associated molecular mechanisms

Abdul Rehman Phull et al.

JOURNAL OF FUNCTIONAL FOODS (2017)

Article Cell Biology

Fucoidan Induces Cell Aggregation and Apoptosis in Osteosarcoma MG-63 Cells

Hyeseon Kim et al.

ANIMAL CELLS AND SYSTEMS (2016)

Article Biochemistry & Molecular Biology

In vitro anti-HIV-1 activity of fucoidan from Sargassum swartzii

Subramaniam Dinesh et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2016)

Article Biochemistry & Molecular Biology

Low molecular weight fucoidan modulates P-selectin and alleviates diabetic nephropathy

Yingjie Xu et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2016)

Article Biochemistry & Molecular Biology

In vitro and in vivo hypoglycemic effects of brown algal fucoidans

Xindi Shan et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2016)

Review Pharmacology & Pharmacy

Prevalence and prevention of cardiovascular disease and diabetes mellitus

Pitchai Balakumar et al.

PHARMACOLOGICAL RESEARCH (2016)

Article Toxicology

Immunomodulatory potential of Rhein, an anthraquinone moiety of Cassia occidentalis seeds

Gati Krushna Panigrahi et al.

TOXICOLOGY LETTERS (2016)

Article Public, Environmental & Occupational Health

Global burden of cancers attributable to infections in 2012: a synthetic analysis

Martyn Plummer et al.

LANCET GLOBAL HEALTH (2016)

Article Chemistry, Applied

Anti-HIV activity of fucoidans from three brown seaweed species

Thanh Thi Thu Thuy et al.

CARBOHYDRATE POLYMERS (2015)

Review Integrative & Complementary Medicine

Advances in the Research and Development of Natural Health Products as Main Stream Cancer Therapeutics

Pamela Ovadje et al.

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2015)

Article Biochemistry & Molecular Biology

Fucoidan delays apoptosis and induces pro-inflammatory cytokine production in human neutrophils

Jun-O Jin et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2015)

Article Biochemistry & Molecular Biology

Fucoidan - A alpha-D-glucosidase inhibitor from Sargassum wightii with relevance to type 2 diabetes mellitus therapy

T. Vinoth Kumar et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2015)

Review Medicine, General & Internal

Defeating AIDS-advancing global health

Peter Piot et al.

LANCET (2015)

Review Chemistry, Medicinal

Therapies from Fucoidan: An Update

Janet Helen Fitton et al.

MARINE DRUGS (2015)

Article Chemistry, Medicinal

Intestinal Absorption of Fucoidan Extracted from the Brown Seaweed, Cladosiphon okamuranus

Takeaki Nagamine et al.

MARINE DRUGS (2015)

Article Clinical Neurology

2014 Alzheimer's disease facts and figures

Alzheimers & Dementia (2014)

Article Biochemistry & Molecular Biology

Autophagy and apoptosis: where do they meet?

Subhadip Mukhopadhyay et al.

APOPTOSIS (2014)

Review Biochemical Research Methods

Bioactive fungal polysaccharides as potential functional ingredients in food and nutraceuticals

Ioannis Giavasis

CURRENT OPINION IN BIOTECHNOLOGY (2014)

Article Food Science & Technology

AKT signaling is involved in fucoidan-induced inhibition of growth and migration of human bladder cancer cells

Tae-Min Cho et al.

FOOD AND CHEMICAL TOXICOLOGY (2014)

Article Chemistry, Medicinal

Effect of Fucoidan Administration on Insulin Secretion and Insulin Resistance in Overweight or Obese Adults

Diana M. Hernandez-Corona et al.

JOURNAL OF MEDICINAL FOOD (2014)

Article Medicine, Research & Experimental

Fucoidan induces caspase-dependent apoptosis in MC3 human mucoepidermoid carcinoma cells

Hang-Eun Lee et al.

EXPERIMENTAL AND THERAPEUTIC MEDICINE (2014)

Article Public, Environmental & Occupational Health

Global causes of maternal death: a WHO systematic analysis

Lale Say et al.

LANCET GLOBAL HEALTH (2014)

Article Biochemistry & Molecular Biology

Fucoidan induces G1 phase arrest and apoptosis through caspases-dependent pathway and ROS induction in human breast cancer MCF-7 cells

Amal M. Banafa et al.

JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY-MEDICAL SCIENCES (2013)

Article Chemistry, Medicinal

Fucoidans as Potential Inhibitors of HIV-1

Maria M. Prokofjeva et al.

MARINE DRUGS (2013)

Article Chemistry, Medicinal

The Anticancer Effect of Fucoidan in PC-3 Prostate Cancer Cells

Hye-Jin Boo et al.

MARINE DRUGS (2013)

Review Physiology

MECHANISMS OF DIABETIC COMPLICATIONS

Josephine M. Forbes et al.

PHYSIOLOGICAL REVIEWS (2013)

Review Biotechnology & Applied Microbiology

Algal fucoidan: structural and size-dependent bioactivities and their perspectives

V. K. Morya et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2012)

Article Environmental Sciences

Fucoidan, a sulfated polysaccharide from brown algae, improves cognitive impairment induced by infusion of Aβ peptide in rats

Yonglin Gao et al.

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2012)

Review Neurosciences

Amyloid Precursor Protein Processing and Alzheimer's Disease

Richard J. O'Brien et al.

ANNUAL REVIEW OF NEUROSCIENCE, VOL 34 (2011)

Article Biochemistry & Molecular Biology

Fucoidans from Brown Seaweeds Sargassum hornery, Eclonia cava, Costaria costata: Structural Characteristics and Anticancer Activity

Svetlana Ermakova et al.

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY (2011)

Article Public, Environmental & Occupational Health

Global mesothelioma deaths reported to the World Health Organization between 1994 and 2008

Vanya Delgermaa et al.

BULLETIN OF THE WORLD HEALTH ORGANIZATION (2011)

Review Environmental Sciences

Potential pharmacological applications of polyphenolic derivatives from marine brown algae

Noel Vinay Thomas et al.

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2011)

Review Physiology

It Is Not About the Bike, It Is About the Pedaling: Forced Exercise and Parkinson's Disease

Jay L. Alberts et al.

EXERCISE AND SPORT SCIENCES REVIEWS (2011)

Article Biochemistry & Molecular Biology

Immunostimulatory Activity of Fucoidan from the Brown Alga Fucus evanescens: Role of Sulfates and Acetates

Stanislav R. Khil'chenko et al.

JOURNAL OF CARBOHYDRATE CHEMISTRY (2011)

Review Chemistry, Medicinal

Neuroprotective Effects of Marine Algae

Ratih Pangestuti et al.

MARINE DRUGS (2011)

Review Chemistry, Medicinal

Therapies from Fucoidan; Multifunctional Marine Polymers

Janet Helen Fitton

MARINE DRUGS (2011)

Article Ophthalmology

Inflammation in diabetic retinopathy

Johnny Tang et al.

PROGRESS IN RETINAL AND EYE RESEARCH (2011)

Review Food Science & Technology

Bioactive potential and possible health effects of edible brown seaweeds

Shilpi Gupta et al.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2011)

Article Biochemistry & Molecular Biology

Fucoidin enhances dendritic cell-mediated T-cell cytotoxicity against NY-ESO-1 expressing human cancer cells

Yaling Hu et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)

Article Biochemistry & Molecular Biology

Development of a Fucoidan-Specific Antibody and Measurement of Fucoidan in Serum and Urine by Sandwich ELISA

Yoshiharu Tokita et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2010)

Article Gastroenterology & Hepatology

Fucoidan present in brown algae induces apoptosis of human colon cancer cells

Eun Ji Kim et al.

BMC GASTROENTEROLOGY (2010)

Article Biochemistry & Molecular Biology

Further studies on the composition and structure of a fucoidan preparation from the brown alga Saccharina latissima

Maria I. Bilan et al.

CARBOHYDRATE RESEARCH (2010)

Article Cell Biology

Fucoidan increases TNF-alpha-induced MMP-9 secretion in monocytic cell line U937

Sun Jintang et al.

INFLAMMATION RESEARCH (2010)

Article Biochemistry & Molecular Biology

Structural studies on a novel fucogalactan sulfate extracted from the brown seaweed Laminaria japonica

Jing Wang et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2010)

Article Biochemistry & Molecular Biology

Different Suppressive Effects of Fucoidan and Lentinan on IL-8 mRNA Expression in in Vitro Gut Inflammation

Masashi Mizuno et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2009)

Article Pharmacology & Pharmacy

Fucoidan protects against dopaminergic neuron death in vivo and in vitro

Dingzhen Luo et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2009)

Article Biochemistry & Molecular Biology

Structural characteristics and in vitro macrophage activation of acetyl fucoidan from Cladosiphon okamuranus

Takeshi Teruya et al.

GLYCOCONJUGATE JOURNAL (2009)

Article Agriculture, Multidisciplinary

Fucoidan Induces Apoptosis through Activation of Caspase-8 on Human Breast Cancer MCF-7 Cells

Yumi Yamasaki-Miyamoto et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2009)

Review Biotechnology & Applied Microbiology

Environmental-induced oxidative stress in neurodegenerative disorders and aging

Lucia Migliore et al.

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2009)

Article Chemistry, Medicinal

Antiretroviral Activity of Fucoidans Extracted from the Brown Seaweed Adenocystis utricularis

Juan Trinchero et al.

PHYTOTHERAPY RESEARCH (2009)

Article Immunology

Fucoidan stimulation induces a functional maturation of human monocyte-derived dendritic cells

Meixiang Yang et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2008)

Article Biochemistry & Molecular Biology

Anti-proliferative activity of oversulfated fucoidan from commercially cultured Cladosiphon okamuranus TOKIDA in U937 cells

Takeshi Teruya et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2007)

Article Biochemistry & Molecular Biology

Polysaccharide and lipid composition of the brown seaweed Laminaria gurjanovae

N. M. Shevchenko et al.

RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY (2007)

Review Pathology

Apoptosis: A review of programmed cell death

Susan Elmore

TOXICOLOGIC PATHOLOGY (2007)

Article Biochemistry & Molecular Biology

Fucoidan prevents Cε germline transcription and NFκB p52 translocation for IgE production in B cells

Souichi Oomizu et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)

Review Chemistry, Organic

Small molecule natural products in the discovery of therapeutic agents: The synthesis connection

Rebecca M. Wilson et al.

JOURNAL OF ORGANIC CHEMISTRY (2006)

Article Gastroenterology & Hepatology

Epidemiology and risk factors for pancreatic cancer

AB Lowenfels et al.

BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY (2006)

Article Biochemistry & Molecular Biology

Structure of a fucoidan from the brown seaweed Fucus serratus L.

MI Bilan et al.

CARBOHYDRATE RESEARCH (2006)

Article Biochemistry & Molecular Biology

A highly regular fraction of a fucoidan from the brown seaweed Fucus distichus L.

MI Bilan et al.

CARBOHYDRATE RESEARCH (2004)

Review Biochemistry & Molecular Biology

Sulfated seaweed polysaccharides as antiviral agents

EB Damonte et al.

CURRENT MEDICINAL CHEMISTRY (2004)

Article Nutrition & Dietetics

The developmental origins of adult disease

DJP Barker

JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION (2004)

Article Biochemistry & Molecular Biology

In vitro anti-herpetic activity of sulfated polysaccharide fractions from Caulerpa racemosa

P Ghosh et al.

PHYTOCHEMISTRY (2004)

Review Pharmacology & Pharmacy

Genealogy, expression, and molecular mechanisms in apoptosis

Z Dlamini et al.

PHARMACOLOGY & THERAPEUTICS (2004)

Review Medicine, General & Internal

Polycystic ovary syndrome and endometrial carcinoma

P Hardiman et al.

LANCET (2003)

Article Integrative & Complementary Medicine

Bioactive polysaccharides from traditional Chinese medicine herbs as anticancer adjuvants

R Chang

JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE (2002)

Article Biochemistry & Molecular Biology

A fucoidan fraction from Ascophyllum nodosum

MF Marais et al.

CARBOHYDRATE RESEARCH (2001)

Article Biochemistry & Molecular Biology

Structural studies on fucoidans from the brown seaweed Sargassum stenophyllum

MER Duarte et al.

CARBOHYDRATE RESEARCH (2001)

Article Biochemistry & Molecular Biology

A disaccharide repeat unit is the major structure in fucoidans from two species of brown algae

L Chevolot et al.

CARBOHYDRATE RESEARCH (2001)