Journal
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
Volume 164, Issue -, Pages 963-975Publisher
ELSEVIER
DOI: 10.1016/j.ijbiomac.2020.07.160
Keywords
Carboxymethyl cellulose; Wound dressing; Biomedical; Antimicrobial
Funding
- FONDECYT [3190029]
- CONICYT [R17A10003]
- University Grants Commission [CH/15[HYPHEN]16/0251]
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The development of ideal wound dressing materials with excellent characteristics is currently a major demand in wound therapy. In recent years, carboxymethyl cellulose (CMC)-based wound dressing materials have been of immense attraction due to their noble properties, such as: biocompatibility, biodegradability, tissue resembling, low cost and non-toxic. It is used extensively, in a variety of applications in the biomedical and pharmaceutical fields. The hydrophilic nature of CMC, makes it possible to blend and cross-link with other materials, such as: synthetic polymers, natural polymers and inorganic materials and it enables the preparation of innovative wound dressing biomaterials. Hence, this review, focuses on the intrinsic characteristics of CMC-based wound dressing materials, including hydrogels, films, 3D printing, fibres, gauzes and their recent advancements in chronic wound healing. (C) 2020 Elsevier B.V. All rights reserved.
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