Advances in the extraction, purification, structural-property relationships and bioactive molecular mechanism of Flammulina velutipes polysaccharides: A review

With the further research in recent years, Flammulina velutipes (F. velutipes), an edible mushroom, has great application value in many fields. As one of the main bioactive components in F. velutipes, polysaccharide has a series of functions such as anti-oxidation, immune regulation, anti-inflammation, liver protection, anti-tumor, anti-hyperlipidemia and so on. In this paper, the current progress in the extraction, purification, structural characteristics and bioactivities of F. velutipes polysaccharides (FVPs) were reviewed. Meanwhile, the structural-property relationships of FVPs were further discussed. In addition, based on in vitro and in vivo experiments, the possible mechanisms of bioactivities of FVPs were summarized. In order to understand FVPs more comprehensively, the application status and the future research work of FVPs were also introduced. Finally, we hope that our research can provide a reference for further research and development of FVPs. (C) 2020 Elsevier B.V. All rights reserved.

Automated summary

This paper reviews the extraction, purification, structural characteristics, and bioactivities of Flammulina velutipes polysaccharides (FVPs), as well as discusses the structural-property relationships. The possible mechanisms of bioactivities were summarized based on in vitro and in vivo experiments, along with the current application status and future research directions of FVPs. The research aims to provide a reference for the further development of FVPs.