☆ 4.8 Letter

Analytical Mistakes Confound Attempted Validation: A Response to Transcription and DNA Methylation Patterns of Blood-Derived CD8+T Cells Are Associated With Age and Inflammatory Bowel Disease But Do Not Predict Prognosis Reply

GASTROENTEROLOGY (2021)

Related references

Note: Only part of the references are listed.

Article Gastroenterology & Hepatology

Transcription and DNA Methylation Patterns of Blood-Derived CD8+ T Cells Are Associated With Age and Inflammatory Bowel Disease But Do Not Predict Prognosis

Marco Gasparetto et al.

Summary: The study aimed to validate the correlation between CD8(+) T-cell gene expression and disease outcome in IBD patients, but failed to reproduce the previously reported findings. It highlights the challenges of developing prognostic biomarkers for IBD patients and stresses the importance of validation in large, independent cohorts before clinical application.

GASTROENTEROLOGY (2021)

Add to Collection

Editorial Material Gastroenterology & Hepatology