4.7 Article

Diagnosis and treatment of infertility in men: AUA/ASRM guideline part II

Journal

FERTILITY AND STERILITY
Volume 115, Issue 1, Pages 62-69

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2020.11.016

Keywords

Male infertility; evaluation; chemotherapy; surgery; health

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This study presents Part II of the Diagnosis and Treatment of Infertility in Men guideline, focusing on the appropriate management of male infertility in infertile couples and various treatment options. The guideline offers evidence-based recommendations for the management of male infertility, which are summarized in an associated algorithm for easier reference and implementation.
Purpose: The summary presented herein represents Part II of the two-part series dedicated to the Diagnosis and Treatment of Infertility in Men: AUA/ASRM Guideline. Part II outlines the appropriate management of the male in an infertile couple. Medical therapies, surgical techniques, as well as use of intrauterine insemination (IUI)/in vitro fertilization (IVF)/intracyloplasmic sperm injection (ICSI) are covered to allow for optimal patient management. Please refer to Part I for discussion on evaluation of the infertile male and discussion of relevant health conditions that are associated with male infertility. Materials/Methods: The Emergency Care Research Institute Evidence-based Practice Center team searched PubMed (R), Embase (R), and Medline from January 2000 through May 2019. When sufficient evidence existed, the body of evidence was assigned a strength rating of A (high), B (moderate), or C (low) for support of Strong, Moderate, or Conditional Recommendations. In the absence of sufficient evidence, additional information is provided as Clinical Principles and Expert Opinions. (Table 1) This summary is being simultaneously published in Fertility and Sterility and The Journal of Urology. Results: This Guideline provides updated, evidence-based recommendations regarding management of male infertility. Such recommendations are summarized in the associated algorithm. (Figure 1) Conclusion: Male contributions to infertility are prevalent, and specific treatment as well as assisted reproductive techniques arc effective at managing male infertility. This document will undergo additional literature reviews and updating as the knowledge regarding current treatments and future treatment options continues to expand. (C) 2020 by American Urological Association Education and Research, Inc. and American Society for Reproductive Medicine.

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