Related references
Note: Only part of the references are listed.Phase separation of TPX2 enhances and spatially coordinates microtubule nucleation
Matthew R. King et al.
NATURE COMMUNICATIONS (2020)
Ivermectin Inhibits Bovine Herpesvirus 1 DNA Polymerase Nuclear Import and Interferes With Viral Replication
Sohail Raza et al.
MICROORGANISMS (2020)
The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro
Leon Caly et al.
ANTIVIRAL RESEARCH (2020)
Karyopherin Kap114p-mediated trans-repression controls ribosomal gene expression under saline stress
Chung-Chi Liao et al.
EMBO REPORTS (2020)
Molecular dissection of an inhibitor targeting the HIV integrase dependent preintegration complex nuclear import
Kylie M. Wagstaff et al.
CELLULAR MICROBIOLOGY (2019)
Zika Virus NS5 Forms Supramolecular Nuclear Bodies That Sequester Importin-α and Modulate the Host Immune and Pro-Inflammatory Response in Neuronal Cells
Ivan H. W. Ng et al.
ACS INFECTIOUS DISEASES (2019)
Molecular interactions underlying liquid-liquid phase separation of the FUS low-complexity domain
Anastasia C. Murthy et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2019)
Ran pathway-independent regulation of mitotic Golgi disassembly by Importin-α
Chih-Chia Chang et al.
NATURE COMMUNICATIONS (2019)
Importin α Partitioning to the Plasma Membrane Regulates Intracellular Scaling
Christopher Brownlee et al.
CELL (2019)
Contribution of the residue at position 4 within classical nuclear localization signals to modulating interaction with importins and nuclear targeting
Kate M. Smith et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2018)
Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites
Takuya Yoshizawa et al.
CELL (2018)
Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation
Mario Hofweber et al.
CELL (2018)
Controlling the Gatekeeper: Therapeutic Targeting of Nuclear Transport
Friederike K. Kosyna et al.
CELLS (2018)
Regulation of mitotic spindle assembly factor NuMA by Importin-β
Chih-Chia Chang et al.
JOURNAL OF CELL BIOLOGY (2017)
BLADE-ON-PETIOLE proteins act in an E3 ubiquitin ligase complex to regulate PHYTOCHROME INTERACTING FACTOR 4 abundance
Bo Zhang et al.
ELIFE (2017)
Compositional Control of Phase-Separated Cellular Bodies
Salman F. Banani et al.
CELL (2016)
Phase separation in biology; functional organization of a higher order
Diana M. Mitrea et al.
CELL COMMUNICATION AND SIGNALING (2016)
Molecular Mechanism of HIV-1 Vpr for Binding to Importin-α
Hideyuki Miyatake et al.
JOURNAL OF MOLECULAR BIOLOGY (2016)
Hypo- and Hyper-Assembly Diseases of RNA-Protein Complexes
Siddharth Shukla et al.
TRENDS IN MOLECULAR MEDICINE (2016)
The Nuclear Transport Factor Kap121 Is Required for Stability of the Dam1 Complex and Mitotic Kinetochore Bi-orientation
Lucas V. Cairo et al.
CELL REPORTS (2016)
Diversification of importin-α isoforms in cellular trafficking and disease states
Ruth A. Pumroy et al.
BIOCHEMICAL JOURNAL (2015)
GM130 Regulates Golgi-Derived Spindle Assembly by Activating TPX2 and Capturing Microtubules
Jen-Hsuan Wei et al.
CELL (2015)
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
Avinash Patel et al.
CELL (2015)
A Comparative Analysis of Spindle Morphometrics across Metazoans
Marina E. Crowder et al.
CURRENT BIOLOGY (2015)
Nuclear transport factors: global regulation of mitosis
Douglass J. Forbes et al.
CURRENT OPINION IN CELL BIOLOGY (2015)
Conservation of inner nuclear membrane targeting sequences in mammalian Pom121 and yeast Heh2 membrane proteins
Annemarie Kralt et al.
MOLECULAR BIOLOGY OF THE CELL (2015)
Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II
Kathleen A. Burke et al.
MOLECULAR CELL (2015)
Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles
Timothy J. Nott et al.
MOLECULAR CELL (2015)
Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2
Ravi K. Lokareddy et al.
STRUCTURE (2015)
Molecular Determinants for Nuclear Import of Influenza A PB2 by Importin α Isoforms 3 and 7
Ruth A. Pumroy et al.
STRUCTURE (2015)
Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1
Wei Xu et al.
CELL HOST & MICROBE (2014)
Autosomal recessive mutations in nuclear transport factor KPNA7 are associated with infantile spasms and cerebellar malformation
Alex R. Paciorkowski et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2014)
Importin-α7 Is Required for Enhanced Influenza A Virus Replication in the Alveolar Epithelium and Severe Lung Damage in Mice
Patricia Resa-Infante et al.
JOURNAL OF VIROLOGY (2014)
mRNP granules Assembly, function, and connections with disease
J. Ross Buchan
RNA BIOLOGY (2014)
Kinetochores require oligomerization of Dam1 complex to maintain microtubule attachments against tension and promote biorientation
Neil T. Umbreit et al.
NATURE COMMUNICATIONS (2014)
Structural basis for the selective nuclear import of the C2H2 zinc-finger protein Snail by importin β
Saehae Choi et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2014)
ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules
Caroline Vance et al.
HUMAN MOLECULAR GENETICS (2013)
Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons
Wen-Yuan Wang et al.
NATURE NEUROSCIENCE (2013)
RNA Seeds Higher-Order Assembly of FUS Protein
Jacob C. Schwartz et al.
CELL REPORTS (2013)
Ivermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virus
Kylie M. Wagstaff et al.
BIOCHEMICAL JOURNAL (2012)
Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels
Masato Kato et al.
CELL (2012)
Phase transitions in the assembly of multivalent signalling proteins
Pilong Li et al.
NATURE (2012)
Structural and energetic basis of ALS-causing mutations in the atypical proline-tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS)
Zi Chao Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Human-like PB2 627K Influenza Virus Polymerase Activity Is Regulated by Importin-α1 and -α7
Ben Hudjetz et al.
PLOS PATHOGENS (2012)
Importazole, a Small Molecule Inhibitor of the Transport Receptor Importin-β
Jonathan F. Soderholm et al.
ACS CHEMICAL BIOLOGY (2011)
How viruses access the nucleus
Sarah Cohen et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
The importin β binding domain as a master regulator of nucleocytoplasmic transport
Kaylen Lott et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
Nuclear import by karyopherin-βs: Recognition and inhibition
Yuh Min Chook et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
Ran-dependent nuclear export mediators: a structural perspective
Thomas Guettler et al.
EMBO JOURNAL (2011)
Differential use of importin-alpha isoforms governs cell tropism and host adaptation of influenza virus
Guelsah Gabriel et al.
NATURE COMMUNICATIONS (2011)
ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import
Dorothee Dormann et al.
EMBO JOURNAL (2010)
Novel Binding of the Mitotic Regulator TPX2 (Target Protein for Xenopus Kinesin-like Protein 2) to Importin-α
Astrid Giesecke et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Novel Importin-α Family Member Kpna7 Is Required for Normal Fertility and Fecundity in the Mouse
Jianjun Hu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Structure of RCC1 chromatin factor bound to the nucleosome core particle
Ravindra D. Makde et al.
NATURE (2010)
Translocation through the nuclear pore: Kaps pave the way
Reiner Peters
BIOESSAYS (2009)
Mechanisms and Signals for the Nuclear Import of Proteins
Natalia Freitas et al.
CURRENT GENOMICS (2009)
Inhibition of Human Cytomegalovirus Replication via Peptide Aptamers Directed against the Nonconventional Nuclear Localization Signal of the Essential Viral Replication Factor pUL84
Nina Kaiser et al.
JOURNAL OF VIROLOGY (2009)
Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic Reticulum/Golgi membrane
Matthew Frieman et al.
JOURNAL OF VIROLOGY (2007)
Tension applied through the Dam1 complex promotes microtubule elongation providing a direct mechanism for length control in mitosis
Andrew D. Franck et al.
NATURE CELL BIOLOGY (2007)
Highway to the inner nuclear membrane: rules for the road
C. Patrick Lusk et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit
Franck Tarendeau et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
Classical nuclear localization signals:: Definition, function, and interaction with importin α
Allison Lange et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Molecular mechanism of the nuclear protein import cycle
Murray Stewart
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Dynamic nuclear pore complexes: Life on the edge
Elizabeth J. Tran et al.
CELL (2006)
Karyopherin flexibility in nucleocytoplasmic transport
E Conti et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2006)
Solution structure of the Ran-binding domain 2 of RanBP2 and its interaction with the C terminus of Ran
JP Geyer et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
NF-κB is transported into the nucleus by importin α3 and importin α4
R Fagerlund et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
A systems analysis of importin-α-β mediated nuclear protein import
G Riddick et al.
JOURNAL OF CELL BIOLOGY (2005)
The Ras superfamily at a glance
K Wennerberg et al.
JOURNAL OF CELL SCIENCE (2005)
Importin a associates with membranes and participates in nuclear envelope assembly in vitro
V Hachet et al.
EMBO JOURNAL (2004)
Importin α:: a multipurpose nuclear-transport receptor
DS Goldfarb et al.
TRENDS IN CELL BIOLOGY (2004)
Evaluation of the functional involvement of human immunodeficiency virus type 1 cDNA during integrase in nuclear import of viral acute infection
T Ikeda et al.
JOURNAL OF VIROLOGY (2004)
The structure of importin-β bound to SREBP-2:: Nuclear import of a transcription factor
SJ Lee et al.
SCIENCE (2003)
P446L-importin-β inhibits nuclear envelope assembly by sequestering nuclear envelope assembly factors to the microtubules
L Tirián et al.
EUROPEAN JOURNAL OF CELL BIOLOGY (2003)
Importin α-regulated nucleation of microtubules by TPX2
CA Schatz et al.
EMBO JOURNAL (2003)
Intersection of the Kap123p-mediated nuclear import and ribosome export pathways
Y Sydorskyy et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Biochemical and functional characterization of the Ebola virus VP24 protein: Implications for a role in virus assembly and budding
ZY Han et al.
JOURNAL OF VIROLOGY (2003)
Ran GTPase cycle and importins α and β are essential for spindle formation and nuclear envelope assembly in living Caenorhabditis elegans embryos
P Askjaer et al.
MOLECULAR BIOLOGY OF THE CELL (2002)
Molecular basis for the recognition of a nonclassical nuclear localization signal by importin β
G Cingolani et al.
MOLECULAR CELL (2002)
Proteomic analysis of the mammalian nuclear pore complex
JA Cronshaw et al.
JOURNAL OF CELL BIOLOGY (2002)
Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-α
KM McBride et al.
EMBO JOURNAL (2002)
The GTPase Ran regulates chromosome positioning and nuclear envelope assembly in vivo
C Bamba et al.
CURRENT BIOLOGY (2002)
RanGAP mediates GTP hydrolysis without an arginine finger
MJ Seewald et al.
NATURE (2002)
Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains
S Jäkel et al.
EMBO JOURNAL (2002)
Karyopherins and nuclear import
YM Chook et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2001)
Signal transduction - The guanine nucleotide-binding switch in three dimensions
IR Vetter et al.
SCIENCE (2001)
Biophysical characterization of interactions involving importin-α during nuclear import
B Catimel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
HIV-1 infection requires a functional integrase NLS
M Bouyac-Bertoia et al.
MOLECULAR CELL (2001)
Involvement of the pro-oncoprotein TLS (translocated in liposarcoma) in nuclear factor-κB p65-mediated transcription as a coactivator
H Uranishi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Importin β is a mitotic target of the small GTPase ran in spindle assembly
MV Nachury et al.
CELL (2001)
Targeting of C-terminal (tail)-anchored proteins: Understanding how cytoplasmic activities are anchored to intracellular membranes
B Wattenberg et al.
TRAFFIC (2001)
The mechanism of Ran import into the nucleus by nuclear transport factor 2
BB Quimby et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-α
MRM Fontes et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)
Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin α
E Conti et al.
STRUCTURE (2000)
The yeast nuclear pore complex: Composition, architecture, and transport mechanism
MP Rout et al.
JOURNAL OF CELL BIOLOGY (2000)