Related references
Note: Only part of the references are listed.The genetic architecture of ALS
Aleksey Shatunov et al.
NEUROBIOLOGY OF DISEASE (2021)
Acetyltransferase GCN5 regulates autophagy and lysosome biogenesis by targeting TFEB
Yusha Wang et al.
EMBO REPORTS (2020)
Dysregulation of histone acetylation pathways in hippocampus and frontal cortex of Alzheimer?s disease patients
Estelle Schueller et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2020)
SIRT7 depletion inhibits cell proliferation and androgen-induced autophagy by suppressing the AR signaling in prostate cancer
Mao Ding et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2020)
Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy
Xu Chen et al.
MOLECULAR NEURODEGENERATION (2020)
The ATG conjugation systems in autophagy
Noboru Mizushima
CURRENT OPINION IN CELL BIOLOGY (2020)
Mendelian neurodegenerative disease genes involved in autophagy
Eleanna Stamatakou et al.
CELL DISCOVERY (2020)
Leucine regulates autophagy via acetylation of the mTORC1 component raptor
Sung Min Son et al.
NATURE COMMUNICATIONS (2020)
Structure, lipid scrambling activity and role in autophagosome formation of ATG9A
Shintaro Maeda et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2020)
Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion
Kazuaki Matoba et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2020)
Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A
Sung Min Son et al.
CELL METABOLISM (2019)
Increase in HDAC9 suppresses myoblast differentiation via epigenetic regulation of autophagy in hypoxia
Zhang Zhang et al.
CELL DEATH & DISEASE (2019)
Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing
Farah H. Siddiqi et al.
NATURE COMMUNICATIONS (2019)
SIRT5-mediated deacetylation of LDHB promotes autophagy and tumorigenesis in colorectal cancer
Liang Shi et al.
MOLECULAR ONCOLOGY (2019)
The many lives of KATs - detectors, integrators and modulators of the cellular environment
Bilal N. Sheikh et al.
NATURE REVIEWS GENETICS (2019)
Functions and mechanisms of non-histone protein acetylation
Takeo Narita et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
Induction of Apoptosis and Autophagy in Breast Cancer Cells by a Novel HDAC8 Inhibitor
Chang-Fang Chiu et al.
BIOMOLECULES (2019)
Frontal Cortex Epigenetic Dysregulation During the Progression of Alzheimer's Disease
Laura Mahady et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
Restoring Tip60 HAT/HDAC2 Balance in the Neurodegenerative Brain Relieves Epigenetic Transcriptional Repression and Reinstates Cognition
Priyalakshmi Panikker et al.
JOURNAL OF NEUROSCIENCE (2018)
Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells
Sara Iachettini et al.
CELL DEATH & DISEASE (2018)
Inhibition of HDAC3 reverses Alzheimer's disease-related pathologies in vitro and in the 3xTg-AD mouse model
Karolina J. Janczura et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Sirtuins and Their Roles in Brain Aging and Neurodegenerative Disorders
Henryk Jesko et al.
NEUROCHEMICAL RESEARCH (2017)
Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities
Fiona M. Menzies et al.
NEURON (2017)
Proteome-wide acetylation dynamics in human cells
Yekaterina Kori et al.
SCIENTIFIC REPORTS (2017)
SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy
Alexander Lang et al.
AGING-US (2017)
A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction
Ana Lopez et al.
BRAIN (2017)
mTOR Signaling in Growth, Metabolism, and Disease
Robert A. Saxton et al.
CELL (2017)
Mammalian Autophagy: How Does It Work?
Carla F. Bento et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 85 (2016)
The world of protein acetylation
Adrian Drazic et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2016)
P300/CBP-associated factor (PCAF) inhibits the growth of hepatocellular carcinoma by promoting cell autophagy
Yu-Li Jia et al.
CELL DEATH & DISEASE (2016)
The Acetyl Group Buffering Action of Carnitine Acetyltransferase Offsets Macronutrient-Induced Lysine Acetylation of Mitochondrial Proteins
Michael N. Davies et al.
CELL REPORTS (2016)
Sirtuins: double players in Huntington's disease
Luana Naia et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2015)
Therapeutic targeting of autophagy in neurodegenerative and infectious diseases
David C. Rubinsztein et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2015)
ApoE4 and Aβ Oligomers Reduce BDNF Expression via HDAC Nuclear Translocation
Abhik Sen et al.
JOURNAL OF NEUROSCIENCE (2015)
Deacetylation of Nuclear LC3 Drives Autophagy Initiation under Starvation
Rui Huang et al.
MOLECULAR CELL (2015)
HDAC Family Members Intertwined in the Regulation of Autophagy: A Druggable Vulnerability in Aggressive Tumor Entities
Emily Koeneke et al.
CELLS (2015)
Assembly and Interrogation of Alzheimer's Disease Genetic Networks Reveal Novel Regulators of Progression
Soline Aubry et al.
PLOS ONE (2015)
Mitochondrial protein acetylation is driven by acetyl-CoA from fatty acid oxidation
Olga Pougovkina et al.
HUMAN MOLECULAR GENETICS (2014)
The growing landscape of lysine acetylation links metabolism and cell signalling
Chunaram Choudhary et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Histone Deacetylase HDAC4 Promotes Gastric Cancer SGC-7901 Cells Progression via p21 Repression
Zhen-Hua Kang et al.
PLOS ONE (2014)
Histone Acetyltransferase p300 Mediates Histone Acetylation of PS1 and BACE1 in a Cellular Model of Alzheimer's Disease
Xi Lu et al.
PLOS ONE (2014)
The emerging role of acetylation in the regulation of autophagy
Agnes Banreti et al.
AUTOPHAGY (2013)
LC3B-II deacetylation by histone deacetylase 6 is involved in serum-starvation-induced autophagic degradation
Kun-Peng Liu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease
Nambirajan Govindarajan et al.
EMBO MOLECULAR MEDICINE (2013)
Hdac6 deletion delays disease progression in the SOD1G93A mouse model of ALS
Ines Taes et al.
HUMAN MOLECULAR GENETICS (2013)
HDAC6 Regulates Mutant SOD1 Aggregation through Two SMIR Motifs and Tubulin Acetylation
Jozsef Gal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy
Jens Fullgrabe et al.
NATURE (2013)
ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase
Ryan C. Russell et al.
NATURE CELL BIOLOGY (2013)
Histone deacetylase 10 promotes autophagy-mediated cell survival
Ina Oehme et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies
David J. Irwin et al.
BRAIN (2012)
The Hairpin-type Tail-Anchored SNARE Syntaxin 17 Targets to Autophagosomes for Fusion with Endosomes/Lysosomes
Eisuke Itakura et al.
CELL (2012)
Histone deacetylase 6 functions as a tumor suppressor by activating c-Jun NH2-terminal kinase-mediated beclin 1-dependent autophagic cell death in liver cancer
Kwang Hwa Jung et al.
HEPATOLOGY (2012)
Long-term memory deficits in Huntingtons disease are associated with reduced CBP histone acetylase activity
A. Giralt et al.
HUMAN MOLECULAR GENETICS (2012)
SIRT1 Protects against α-Synuclein Aggregation by Activating Molecular Chaperones
Gizem Donmez et al.
JOURNAL OF NEUROSCIENCE (2012)
Suppression of aggregate formation of mutant huntingtin potentiates CREB-binding protein sequestration and apoptotic cell death
Yong-Joon Choi et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2012)
Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets
Mali Jiang et al.
NATURE MEDICINE (2012)
Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway
Hyunkyung Jeong et al.
NATURE MEDICINE (2012)
Sirtuins as regulators of metabolism and healthspan
Riekelt H. Houtkooper et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Pcaf Modulates Polyglutamine Pathology in a Drosophila Model of Huntington's Disease
Laszlo Bodai et al.
NEURODEGENERATIVE DISEASES (2012)
Tip60 HAT Activity Mediates APP Induced Lethality and Apoptotic Cell Death in the CNS of a Drosophila Alzheimer's Disease Model
Sheila K. Pirooznia et al.
PLOS ONE (2012)
Histone deacetylases 1 and 2 regulate autophagy flux and skeletal muscle homeostasis in mice
Viviana Moresi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy
Shu-Yong Lin et al.
SCIENCE (2012)
Protein N-terminal acetyltransferases: when the start matters
Kristian K. Starheim et al.
TRENDS IN BIOCHEMICAL SCIENCES (2012)
A comprehensive glossary of autophagy-related molecules and processes (2nd edition)
Daniel J. Klionsky et al.
AUTOPHAGY (2011)
Autophagy: Renovation of Cells and Tissues
Noboru Mizushima et al.
CELL (2011)
Physical and Functional HAT/HDAC Interplay Regulates Protein Acetylation Balance
Alessia Peserico et al.
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2011)
Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy
Dian J. Cao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Increased SOD1 association with chromatin, DNA damage, p53 activation, and apoptosis in a cellular model of SOD1-linked ALS
Livea F. Barbosa et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)
microRNA-dependent modulation of histone acetylation in Waldenstrom macroglobulinemia
Aldo M. Roccaro et al.
BLOOD (2010)
Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3
Fiona M. Menzies et al.
BRAIN (2010)
Effects of Longevinex (modified resveratrol) on cardioprotection and its mechanisms of action
Subhendu Mukherjee et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2010)
Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes
Nirmala Hariharan et al.
CIRCULATION RESEARCH (2010)
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6
Fabienne C. Fiesel et al.
EMBO JOURNAL (2010)
HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy
Joo-Yong Lee et al.
EMBO JOURNAL (2010)
Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease
Claudia Rose et al.
HUMAN MOLECULAR GENETICS (2010)
Amyotrophic Lateral Sclerosis-associated Proteins TDP-43 and FUS/TLS Function in a Common Biochemical Complex to Co-regulate HDAC6 mRNA
Sang Hwa Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Differential Histone Deacetylase mRNA Expression Patterns in Amyotrophic Lateral Sclerosis
Claas Janssen et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2010)
Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity
Ying Zhao et al.
NATURE CELL BIOLOGY (2010)
MICE KNOCK OUT FOR THE HISTONE ACETYLTRANSFERASE P300/CREB BINDING PROTEIN-ASSOCIATED FACTOR DEVELOP A RESISTANCE TO AMYLOID TOXICITY
F. Duclot et al.
NEUROSCIENCE (2010)
CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease
Antonella Caccamo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis
Ruth Luthi-Carter et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Acetylation Targets Mutant Huntingtin to Autophagosomes for Degradation
Hyunkyung Jeong et al.
CELL (2009)
Elongator Controls the Migration and Differentiation of Cortical Neurons through Acetylation of α-Tubulin
Catherine Creppe et al.
CELL (2009)
Phosphodiesterase type IV inhibition prevents sequestration of CREB binding protein, protects striatal parvalbumin interneurons and rescues motor deficits in the R6/2 mouse model of Huntington's disease
Carmela Giampa et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2009)
Regulation of Autophagy by the p300 Acetyltransferase
In Hye Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Mammalian macroautophagy at a glance
Brinda Ravikumar et al.
JOURNAL OF CELL SCIENCE (2009)
Sirtuin 1 Reduction Parallels the Accumulation of Tau in Alzheimer Disease
Carl Julien et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2009)
HDAC2 negatively regulates memory formation and synaptic plasticity
Ji-Song Guan et al.
NATURE (2009)
The many roles of histone deacetylases in development and physiology: implications for disease and therapy
Michael Haberland et al.
NATURE REVIEWS GENETICS (2009)
Genomic investigation of α-synuclein multiplication and parkinsonism
Owen A. Ross et al.
ANNALS OF NEUROLOGY (2008)
Inhibition of histone deacetylase1 induces autophagy
Meeyeon Oh et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
Elizabeth L. Axe et al.
JOURNAL OF CELL BIOLOGY (2008)
Histone deacetylase 6 interacts with the microtubule-associated protein tau
Huiping Ding et al.
JOURNAL OF NEUROCHEMISTRY (2008)
SAHA induces caspase-independent, autophagic cell death of endometrial stromal sarcoma cells by influencing the mTOR pathway
A. Hrzenjak et al.
JOURNAL OF PATHOLOGY (2008)
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway
Andrea Williams et al.
NATURE CHEMICAL BIOLOGY (2008)
Deregulation of HDAC1 by p25/Cdk5 in Neurotoxicity
Dohoon Kim et al.
NEURON (2008)
A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy
In Hye Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content
Kurt J. De Vos et al.
HUMAN MOLECULAR GENETICS (2007)
Sirtuin 2 inhibitors rescue α-synuclein-mediated toxicity in models of Parkinson's disease
Tiago Fleming Outeiro et al.
SCIENCE (2007)
Mammalian Sir2-related protein (SIRT) 2-mediated modulation of resistance to axonal degeneration in slow Wallerian degeneration mice: A crucial role of tubulin deacetylation
K. Suzuki et al.
NEUROSCIENCE (2007)
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
Udai Bhan Pandey et al.
NATURE (2007)
Small molecules enhance autophagy and reduce toxicity in Huntington's disease models
Sovan Sarkar et al.
NATURE CHEMICAL BIOLOGY (2007)
α-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity
Eirene Kontopoulos et al.
HUMAN MOLECULAR GENETICS (2006)
HATs and HDACs in neurodegeneration: a tale of disconcerted acetylation homeostasis
RN Saha et al.
CELL DEATH AND DIFFERENTIATION (2006)
Rapamycin pre-treatment protects against apoptosis
B Ravikumar et al.
HUMAN MOLECULAR GENETICS (2006)
HDAC6 and microtubules are required for autophagic degradation of aggregated Huntingtin
A Iwata et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis
YM Jiang et al.
ANNALS OF NEUROLOGY (2005)
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
B Ravikumar et al.
NATURE GENETICS (2004)
Critical loss of CBP/p300 histone acetylase activity by caspase-6 during neurodegeneration
C Rouaux et al.
EMBO JOURNAL (2003)
α-synuclein is degraded by both autophagy and the proteasome
JL Webb et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Cell death triggered by polyglutamine-expanded huntingtin in a neuronal cell line is associated with degradation of CREB-binding protein
HB Jiang et al.
HUMAN MOLECULAR GENETICS (2003)
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy
B Ravikumar et al.
HUMAN MOLECULAR GENETICS (2002)
PML regulates p53 acetylation and premature senescence induced by oncogenic Ras
M Pearson et al.
NATURE (2000)
CREB-binding protein sequestration by expanded polyglutamine
A McCampbell et al.
HUMAN MOLECULAR GENETICS (2000)
Share Paper
