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Two-step strategy for the identification of SARS-CoV-2 variant of concern 202012/01 and other variants with spike deletion H69-V70, France, August to December 2020

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Summary: Four Next-Generation Sequencing methods have shown excellent performance in SARS-CoV-2 whole-genome sequencing, demonstrating high concordance and suitability for samples with different viral loads. However, it is important to consider the characteristics and validation requirements of each method.

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