4.5 Article

Silver-Catalyzed Acyl Nitrene Transfer Reactions Involving Dioxazolones: Direct Assembly of N-Acylureas

Journal

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2021, Issue 4, Pages 648-652

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.202001460

Keywords

C− N bond formation; Silver; Synthetic methods; Transition metals

Funding

  1. Hangzhou Ledun Technology Co., Ltd

Ask authors/readers for more resources

A silver-catalyzed acyl nitrene transfer reaction involving dioxazolones, isocyanides, and water was successfully achieved in this study, leading to the synthesis of a series of N-acylureas in moderate to good yields. This provides a new research direction for the application of dioxazolones and isocyanides in synthetic chemistry.
Dioxazolones and isocyanides are useful synthetic building blocks, and have attracted significant attention from researchers. However, the silver-catalyzed nitrene transfer reaction of dioxazolones has not been investigated to date. Herein, a silver-catalyzed acyl nitrene transfer reaction involving dioxazolones, isocyanides, and water was realized in the presence of Ag2O to afford a series of N-acylureas in moderate to good yields.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.5
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available