On cerebrotoxicity of antihypertensive therapy and risk factor cosmetics

Article Cardiac & Cardiovascular Systems

Midlife blood pressure is associated with the severity of white matter hyperintensities: analysis of the UK Biobank cohort study

Karolina Agnieszka Wartolowska et al.

Summary: The study found that white matter hyperintensities (WMH) are closely related to concurrent and past hypertension, especially with regard to systolic blood pressure. However, before the age of 50, diastolic blood pressure is more strongly correlated with WMH. Long-term prevention of WMH may require control of even mildly elevated midlife diastolic blood pressure.

EUROPEAN HEART JOURNAL (2021)

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Article Cardiac & Cardiovascular Systems

Midlife blood pressure is associated with the severity of white matter hyperintensities: analysis of the UK Biobank cohort study

Karolina Agnieszka Wartolowska et al.

Summary: This study found a strong association between WMH and concurrent/past elevated blood pressure, particularly with a stronger association with systolic blood pressure (SBP). However, before the age of 50, diastolic blood pressure (DBP) was more strongly associated with WMH. Long-term prevention of WMH may require control of even mildly elevated midlife DBP.

EUROPEAN HEART JOURNAL (2021)

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Article Cardiac & Cardiovascular Systems