4.5 Letter

Alteration in cerebrospinal fluid (CSF) markers associated with α-synucleinopathies

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Publisher

SPRINGER HEIDELBERG
DOI: 10.1007/s00406-020-01212-0

Keywords

Parkinson disease; Lewy body dementia; Cerebrospinal fluid; REM sleep behavior disorder

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RBD is associated with Parkinson's disease and Lewy body dementia, and it is crucial to consider and exclude RBD when studying CSF markers in order to improve the specificity of test results.
Rapid eye movement sleep behavior disorder (RBD) is linked to other alpha-synucleinopathies such as Parkinson's disease and Lewy body dementia. It is essential to consider and exclude RBD while studying CSF markers in the latter two to avoid confounding bias and improve test results' specificity.

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