4.7 Review

Xenopus in revealing developmental toxicity and modeling human diseases

Related references

Note: Only part of the references are listed.
Review Clinical Neurology

Wnt/β-Catenin Signaling in Neural Stem Cell Homeostasis and Neurological Diseases

Juanmei Gao et al.

Summary: The Wnt/beta-catenin signaling pathway plays a crucial role in regulating the balance of neural stem/progenitor cells (NSCs) proliferation and differentiation, which is essential for the development and maintenance of the nervous system. Recent findings suggest that components of the Wnt/beta-catenin signaling pathway are involved in the regulation of functional brain circuits, providing potential therapeutic targets for neurological diseases.

NEUROSCIENTIST (2021)

Article Environmental Sciences

The Flavor Enhancer Maltol Increases Pigment Aggregation in Dermal and Neural Melanophores in Xenopus laevis Tadpoles

Lara I. Dahora et al.

ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2020)

Review Pharmacology & Pharmacy

Using Xenopus oocytes in neurological disease drug discovery

Steven L. Zeng et al.

EXPERT OPINION ON DRUG DISCOVERY (2020)

Article Environmental Sciences

Effect of triadimefon and its metabolite on adult amphibians Xenopus laevis

Wenjun Zhang et al.

CHEMOSPHERE (2020)

Article Anatomy & Morphology

Modeling ocular lens disease in Xenopus

Justine Viet et al.

DEVELOPMENTAL DYNAMICS (2020)

Article Multidisciplinary Sciences

Alcohol-derived DNA crosslinks are repaired by two distinct mechanisms

Michael R. Hodskinson et al.

NATURE (2020)

Article Physiology

Modeling Bainbridge-Ropers Syndrome in Xenopus laevis Embryos

Hava Lichtig et al.

FRONTIERS IN PHYSIOLOGY (2020)

Article Biotechnology & Applied Microbiology

MicroRNA expression in the heart of Xenopus laevis facilitates metabolic adaptation to dehydration

Liam J. Hawkins et al.

GENOMICS (2020)

Article Environmental Sciences

Analysis of long non-coding RNA involved in atrazine-induced testicular degeneration of Xenopus laevis

Linlin Sai et al.

ENVIRONMENTAL TOXICOLOGY (2019)

Article Multidisciplinary Sciences

Stage-dependent cardiac regeneration in Xenopus is regulated by thyroid hormone availability

Lindsey N. Marshall et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Review Physiology

Xenbase: Facilitating the Use of Xenopus to Model Human Disease

Mardi J. Nenni et al.

FRONTIERS IN PHYSIOLOGY (2019)

Article Toxicology

Paracetamol-induced liver injury modelled in Xenopus laevis embryos

Katy Saide et al.

TOXICOLOGY LETTERS (2019)

Article Multidisciplinary Sciences

Identification of a regeneration-organizing cell in the Xenopus tail

C. Aztekin et al.

SCIENCE (2019)

Article Environmental Sciences

Comparative Analysis of the Developmental Toxicity in Xenopus laevis and Danio rerio Induced by Al2O3 Nanoparticle Exposure

Tayaba Ismail et al.

ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2019)

Review Environmental Sciences

Tetrabromobisphenol A: Disposition, kinetics and toxicity in animals and humans

Yunjiang Yu et al.

ENVIRONMENTAL POLLUTION (2019)

Article Environmental Sciences

Effects of antidepressants with different modes of action on early life stages of fish and amphibians

Pavia Sehonova et al.

ENVIRONMENTAL POLLUTION (2019)

Review Environmental Sciences

Ecotoxicity of nanomaterials in amphibians: A critical review

Diogo Ferreira do Amaral et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2019)

Review Neurosciences

Valproic Acid and Epilepsy: From Molecular Mechanisms to Clinical Evidences

Michele Romoli et al.

CURRENT NEUROPHARMACOLOGY (2019)

Review Neurosciences

Approaches and Limitations in the Investigation of Synaptic Transmission and Plasticity

Stephen D. Glasgow et al.

FRONTIERS IN SYNAPTIC NEUROSCIENCE (2019)

Review Neurosciences

Neurobiological bases of autism-epilepsy comorbidity: a focus on excitation/inhibition imbalance

Yuri Bozzi et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2018)

Article Biochemistry & Molecular Biology

Evaluation of the toxic effects of celecoxib on Xenopus embryo development

Yeon-Hee Yoon et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)

Review Biochemistry & Molecular Biology

Xenopus embryos to study fetal alcohol syndrome, a model for environmental teratogenesis

Abraham Fainsod et al.

BIOCHEMISTRY AND CELL BIOLOGY (2018)

Review Biochemistry & Molecular Biology

Diving into the world of alcohol teratogenesis: a review of zebrafish models of fetal alcohol spectrum disorder

Yohaan Fernandes et al.

BIOCHEMISTRY AND CELL BIOLOGY (2018)

Article Neurosciences

Muscarinic modulation of the Xenopus laevis tadpole spinal mechanosensory pathway

Nicola Jean Porter et al.

BRAIN RESEARCH BULLETIN (2018)

Article Multidisciplinary Sciences

Unexpected metabolic disorders induced by endocrine disruptors in Xenopus tropicalis provide new lead for understanding amphibian decline

Christophe Regnault et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Environmental Sciences

The role of pparγ in embryonic development of Xenopus tropicalis under triphenyltin-induced teratogenicity

Jingmin Zhu et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2018)

Review Anatomy & Morphology

Xenopus: An Undervalued Model Organism to Study and Model Human Genetic Disease

Martin Blum et al.

CELLS TISSUES ORGANS (2018)

Article Engineering, Environmental

Microplastics in Small Waterbodies and Tadpoles from Yangtze River Delta, China

Lingling Hu et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2018)

Article Environmental Sciences

Polystyrene microplastics did not affect body growth and swimming activity in Xenopus laevis tadpoles

Beatrice De Felice et al.

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2018)

Review Pharmacology & Pharmacy

Advances in the use of Xenopus for successful drug screening

Lorena A. Maia et al.

EXPERT OPINION ON DRUG DISCOVERY (2017)

Review Developmental Biology

Using Xenopus to understand human disease and developmental disorders

Amy K. Sater et al.

GENESIS (2017)

Article Nanoscience & Nanotechnology

Daphnia magna and Xenopus laevis as in vivo models to probe toxicity and uptake of quantum dots functionalized with gH625

Emilia Galdiero et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2017)

Article Nanoscience & Nanotechnology

Teratogenic hazard of BPEI-coated silver nanoparticles to Xenopus laevis

Anita Colombo et al.

NANOTOXICOLOGY (2017)

Article Biochemical Research Methods

Spinal cord regeneration in Xenopus laevis

Gabriela Edwards-Faret et al.

NATURE PROTOCOLS (2017)

Article Biochemistry & Molecular Biology

Heart regeneration in adult Xenopus tropicalis after apical resection

Souqi Liao et al.

CELL AND BIOSCIENCE (2017)

Article Multidisciplinary Sciences

Analysis of Craniocardiac Malformations in Xenopus using Optical Coherence Tomography

Engin Deniz et al.

SCIENTIFIC REPORTS (2017)

Article Developmental Biology

Xenopus egg extract: A powerful tool to study genome maintenance mechanisms

Wouter S. Hoogenboom et al.

DEVELOPMENTAL BIOLOGY (2017)

Article Developmental Biology

High-efficiency non-mosaic CRISPR-mediated knock-in and indel mutation in F0 Xenopus

Yetki Aslan et al.

DEVELOPMENT (2017)

Review Developmental Biology

Expanding the genetic toolkit in Xenopus: Approaches and opportunities for human disease modeling

Panna Tandon et al.

DEVELOPMENTAL BIOLOGY (2017)

Article Cell Biology

Modeling Human Craniofacial Disorders in Xenopus

Aditi Dubey et al.

CURRENT PATHOBIOLOGY REPORTS (2017)

Article Clinical Neurology

Seizure control by decanoic acid through direct AMPA receptor inhibition

Pishan Chang et al.

BRAIN (2016)

Article Toxicology

Developing Xenopus embryos recover by compacting and expelling single wall carbon nanotubes

Brian D. Holt et al.

JOURNAL OF APPLIED TOXICOLOGY (2016)

Article Biochemistry & Molecular Biology

Survival fraction and phenotype alterations of Xenopus laevis embryos at 3 Gy, 150 kV X-ray irradiation

Rosa Carotenuto et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)

Article Environmental Sciences

Teratogenic effects of five anticancer drugs on Xenopus laevis embryo

Marina Isidori et al.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2016)

Article Biochemistry & Molecular Biology

Neural regeneration dynamics of Xenopus laevis olfactory epithelium after zinc sulfate-induced damage

J. L. Frontera et al.

JOURNAL OF CHEMICAL NEUROANATOMY (2016)

Review Cell Biology

Xenopus as a model organism for birth defects Congenital heart disease and heterotaxy

Anna R. Duncan et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2016)

Article Toxicology

Boric Acid Is Reproductively Toxic to Adult Xenopus laevis, but Not Endocrine Active

Douglas J. Fort et al.

TOXICOLOGICAL SCIENCES (2016)

Article Marine & Freshwater Biology

Tebuconazole disrupts steroidogenesis in Xenopus laevis

Rikke Poulsen et al.

AQUATIC TOXICOLOGY (2015)

Article Environmental Sciences

Recovery capabilities of Xenopus laevis after exposure to Cadmium and Zinc

F. Mouchet et al.

CHEMOSPHERE (2015)

Article Developmental Biology

An oncologist's friend: How Xenopus contributes to cancer research

Laura J. A. Hardwick et al.

DEVELOPMENTAL BIOLOGY (2015)

Article Developmental Biology

CRISPR/Cas9: An inexpensive, efficient loss of function tool to screen human disease genes in Xenopus

Dipankan Bhattacharya et al.

DEVELOPMENTAL BIOLOGY (2015)

Article Developmental Biology

Regeneration of Xenopus laevis spinal cord requires Sox2/3 expressing cells

Rosana Munoz et al.

DEVELOPMENTAL BIOLOGY (2015)

Article Environmental Sciences

Proteomics analysis of Xenopus laevis gonad tissue following chronic exposure to atrazine

Xiuping Chen et al.

ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2015)

Article Chemistry, Multidisciplinary

Polystyrene nanoparticles affect Xenopus laevis development

Margherita Tussellino et al.

JOURNAL OF NANOPARTICLE RESEARCH (2015)

Article Neurosciences

Valproate-Induced Neurodevelopmental Deficits in Xenopus laevis Tadpoles

Eric J. James et al.

JOURNAL OF NEUROSCIENCE (2015)

Article Environmental Sciences

Do Nanoparticle Physico-Chemical Properties and Developmental Exposure Window Influence Nano ZnO Embryotoxicity in Xenopus laevis?

Patrizia Bonfanti et al.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2015)

Review Pharmacology & Pharmacy

Engineering Xenopus embryos for phenotypic drug discovery screening

Stefan M. Schmitt et al.

ADVANCED DRUG DELIVERY REVIEWS (2014)

Article Developmental Biology

The Wnt/JNK signaling target gene alcam is required for embryonic kidney development

Wiebke Cizelsky et al.

DEVELOPMENT (2014)

Article Environmental Sciences

Teratogenic effects of organic extracts from the Pearl River sediments on Xenopus laevis embryos

Cong Zhang et al.

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2014)

Article Neurosciences

Excitation and inhibition in recurrent networks mediate collision avoidance in Xenopus tadpoles

Arseny S. Khakhalin et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2014)

Article Agriculture, Multidisciplinary

Potential Protective Effect of L-Cysteine against the Toxicity of Acrylamide and Furan in Exposed Xenopus laevis Embryos: An Interaction Study

John Russell Williams et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2014)

Article Multidisciplinary Sciences

Optic flow instructs retinotopic map formation through a spatial to temporal to spatial transformation of visual information

Masaki Hiramoto et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Neurosciences

FMRP Regulates Neurogenesis In Vivo in Xenopus laevis Tadpoles1,2,3

Regina L. Faulkner et al.

ENEURO (2014)

Review Genetics & Heredity

The Genetic Landscapes of Autism Spectrum Disorders

Guillaume Huguet et al.

ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, VOL 14 (2013)

Article Biotechnology & Applied Microbiology

A genome-wide survey of maternal and embryonic transcripts during Xenopus tropicalis development

Sarita S. Paranjpe et al.

BMC GENOMICS (2013)

Article Neurosciences

Neurogenesis is required for behavioral recovery after injury in the visual system of Xenopus laevis

Caroline R. McKeown et al.

JOURNAL OF COMPARATIVE NEUROLOGY (2013)

Review Neurosciences

In utero exposure to valproic acid and autism - A current review of clinical and animal studies

Florence I. Roullet et al.

NEUROTOXICOLOGY AND TERATOLOGY (2013)

Article Environmental Sciences

Human health risk assessment of air emissions from development of unconventional natural gas resources

Lisa M. McKenzie et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2012)

Article Biochemistry & Molecular Biology

Rapamycin treatment causes developmental delay, pigmentation defects, and gastrointestinal malformation on Xenopus embryogenesis

Yuki Moriyama et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)

Article Developmental Biology

Bisphenol A induces otolith malformations during vertebrate embryogenesis

Yann Gibert et al.

BMC DEVELOPMENTAL BIOLOGY (2011)

Article Environmental Sciences

Acute effects of Fe2O3, TiO2, ZnO and CuO nanomaterials on Xenopus laevis

Shawna Nations et al.

CHEMOSPHERE (2011)

Article Environmental Sciences

Stage-specific malformations and phenotypic changes induced in embryos of amphibian (Xenopus tropicalis) by triphenyltin

Jing Yuan et al.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2011)

Article Neurosciences

Inhibition to excitation ratio regulates visual system responses and behavior in vivo

Wanhua Shen et al.

JOURNAL OF NEUROPHYSIOLOGY (2011)

Article Neurosciences

A neuroprotective role for polyamines in a Xenopus tadpole model of epilepsy

Mark R. Bell et al.

NATURE NEUROSCIENCE (2011)

Article Biochemical Research Methods

A Biochemical Screen for Identification of Small-Molecule Regulators of the Wnt Pathway Using Xenopus Egg Extracts

Curtis A. Thorne et al.

JOURNAL OF BIOMOLECULAR SCREENING (2011)

Review Biotechnology & Applied Microbiology

Key factors in the discovery and development of new antiepileptic drugs

Meir Bialer et al.

NATURE REVIEWS DRUG DISCOVERY (2010)

Article Multidisciplinary Sciences

Atrazine induces complete feminization and chemical castration in male African clawed frogs (Xenopus laevis)

Tyrone B. Hayes et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Endocrinology & Metabolism

Metabolism of the Endocrine Disruptor BPA by Xenopus laevis Tadpoles

Jean-Baptiste Fini et al.

TRENDS IN COMPARATIVE ENDOCRINOLOGY AND NEUROBIOLOGY (2009)

Article Anatomy & Morphology

Toward Defining the Phosphoproteome of Xenopus laevis Embryos

Jered V. McGivern et al.

DEVELOPMENTAL DYNAMICS (2009)

Article Cell Biology

Learning about cancer from frogs: analysis of mitotic spindles in Xenopus egg extracts

Marie K. Cross et al.

DISEASE MODELS & MECHANISMS (2009)

Review Environmental Sciences

Amphibians and agricultural chemicals: Review of the risks in a complex environment

Reinier M. Mann et al.

ENVIRONMENTAL POLLUTION (2009)

Article Toxicology

Rapid responses of a melanophore cell line to chemical contaminants in water

Aurel Luga et al.

JOURNAL OF APPLIED TOXICOLOGY (2009)

Article Biochemistry & Molecular Biology

Xenopus laevis Oocytes Endogenously Express All Subunits of the Ionotropic Glutamate Receptor Family

Carsten Schmidt et al.

JOURNAL OF MOLECULAR BIOLOGY (2009)

Article Marine & Freshwater Biology

Effect of atrazine on metamorphosis and sexual differentiation in Xenopus laevis

Tomohiro Oka et al.

AQUATIC TOXICOLOGY (2008)

Article Neurosciences

In vivo imaging of seizure activity in a novel developmental seizure model

D. Sesath Hewapathirane et al.

EXPERIMENTAL NEUROLOGY (2008)

Article Environmental Sciences

Tire debris organic extract affects Xenopus development

Paride Mantecca et al.

ENVIRONMENT INTERNATIONAL (2007)

Article Biochemistry & Molecular Biology

Isolation of Xenopus HIF-prolyl 4-hydroxylase and rescue of a small-eye phenotype caused by Siah2 over-expression

Susumu Imaoka et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Article Cell Biology

Early molecular effects of ethanol during vertebrate embryogenesis

Ronit Yelin et al.

DIFFERENTIATION (2007)

Article Pharmacology & Pharmacy

The mechanism of carbamazepine aggravation of absence seizures

Lige Liu et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)

Article Biochemistry & Molecular Biology

Unliganded thyroid hormone receptor is essential for Xenopus laevis eye development

Emmanuelle Havis et al.

EMBO JOURNAL (2006)

Article Biochemistry & Molecular Biology

Xenopus as a model organism in developmental chemical genetic screens

ML Tomlinson et al.

MOLECULAR BIOSYSTEMS (2005)

Article Developmental Biology

Developmental expression of Xenopus Fragile X mental retardation-1 gene

JH Lim et al.

INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY (2005)

Article Marine & Freshwater Biology

Effects of agricultural pesticides on the immune system of Xenopus laevis and Rana pipiens

MS Christin et al.

AQUATIC TOXICOLOGY (2004)

Article Multidisciplinary Sciences

Thyroid hormone controls the development of connections between the spinal cord and limbs during Xenopus laevis metamorphosis

N Marsh-Armstrong et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Marine & Freshwater Biology

Comparative teratogenicity of Chlorpyrifos and Malathion on Xenopus laevis development

P Bonfanti et al.

AQUATIC TOXICOLOGY (2004)

Article Engineering, Environmental

Dietary retinoic acid induces hindlimb and eye deformities in Xenopus laevis

DH Alsop et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2004)

Article Ophthalmology

Catalase and peroxiredoxin 5 protect xenopus embryos against alcohol-induced ocular anomalies

Y Peng et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2004)

Review Anatomy & Morphology

Thyroid hormone promotes neurogenesis in the Xenopus spinal cord

G Schlosser et al.

DEVELOPMENTAL DYNAMICS (2002)

Article Multidisciplinary Sciences

Multiple thyroid hormone-induced muscle growth and death programs during metamorphosis in Xenopus laevis

B Das et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Marine & Freshwater Biology

Paraquat embryotoxicity in the Xenopus laevis cleavage phase

C Vismara et al.

AQUATIC TOXICOLOGY (2001)

Article Pharmacology & Pharmacy

Effects of volatile solvents on recombinant N-methyl-D-aspartate receptors expressed in Xenopus oocytes

SL Cruz et al.

BRITISH JOURNAL OF PHARMACOLOGY (2000)