Journal
ENT-EAR NOSE & THROAT JOURNAL
Volume 101, Issue 10, Pages NP441-NP444Publisher
SAGE PUBLICATIONS INC
DOI: 10.1177/0145561320976411
Keywords
IgG4-RD; inner ear; cochlear ossification
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This study describes a case of IgG4-related disease affecting the inner ear and causing cochlear ossification. Cochlear implants and hormone/immunosuppressive therapy can help control disease progression, especially in milder cases.
Immunoglobulin G4-related disease (IgG4-RD) is a chronic inflammatory disease involving multiple organs. Some studies have reported otological manifestations of IgG4-RD, although most studies describe involvement of the middle ear, and reports on inner ear manifestations are limited. Here, we describe a case of a 30-year-old man with IgG4-RD involving the inner ear. This case demonstrated that IgG4-RD affected the inner ear and caused cochlear ossification. Cochlear implants may be considered for milder cases, and hormone and immunosuppressive therapy may control disease progression.
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