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Marily Theodoropoulou et al.
FRONTIERS IN NEUROENDOCRINOLOGY (2013)
Low Accuracy of Tumor Markers for Diagnosing Pancreatic Neuroendocrine Tumors in Multiple Endocrine Neoplasia Type 1 Patients
Joanne M. de Laat et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2013)
Incidence and Prevalence of Primary Hyperparathyroidism in a Racially Mixed Population
Michael W. Yeh et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2013)
Causes of Death and Prognostic Factors in Multiple Endocrine Neoplasia Type 1: A Prospective Study Comparison of 106 MEN1/Zollinger-Ellison Syndrome Patients With 1613 Literature MEN1 Patients With or Without Pancreatic Endocrine Tumors
Tetsuhide Ito et al.
MEDICINE (2013)
Primary hyperparathyroidism in pregnancy
Gonzalo Diaz-Soto et al.
ENDOCRINE (2013)
Expression of Somatostatin Receptor (SSTR) Subtypes (SSTR-1, 2A, 3, 4 and 5) in Neuroendocrine Tumors Using Real-time RT-PCR Method and Immunohistochemistry
Gou Mizutani et al.
ACTA HISTOCHEMICA ET CYTOCHEMICA (2012)
MEN1 and pituitary adenomas
Brigitte Delemer
ANNALES D ENDOCRINOLOGIE (2012)
Primary Hyperparathyroidism in MEN1 Patients A Cohort Study With Longterm Follow-Up on Preferred Surgical Procedure and the Relation With Genotype
Carolina R. C. Pieterman et al.
ANNALS OF SURGERY (2012)
Menin and p53 have non-synergistic effects on tumorigenesis in mice
Kelly A. Loffler et al.
BMC CANCER (2012)
MEN1 Gene Replacement Therapy Reduces Proliferation Rates in a Mouse Model of Pituitary Adenomas
Gerard V. Walls et al.
CANCER RESEARCH (2012)
Novel mutations in MEN1, CDKN1B and AIP genes in patients with multiple endocrine neoplasia type 1 syndrome in Spain
Oihana Belar et al.
CLINICAL ENDOCRINOLOGY (2012)
Cushing's syndrome in multiple endocrine neoplasia type 1
William F. Simonds et al.
CLINICAL ENDOCRINOLOGY (2012)
Multiple endocrine neoplasia type 1 in Japan: establishment and analysis of a multicentre database
Akihiro Sakurai et al.
CLINICAL ENDOCRINOLOGY (2012)
Importance of Surveillance for Multiple Endocrine Neoplasia-1 and Surgery in Patients With Sporadic Zollinger-Ellison Syndrome
Maneesh H. Singh et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2012)
Pasireotide (SOM230) shows efficacy and tolerability in the treatment of patients with advanced neuroendocrine tumors refractory or resistant to octreotide LAR: results from a phase II study
Larry K. Kvols et al.
ENDOCRINE-RELATED CANCER (2012)
Adrenal involvement in MEN1. Analysis of 715 cases from the Groupe d'e ' tude des Tumeurs Endocrines database
B. Gatta-Cherifi et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2012)
Clinical Practice Guidelines for Multiple Endocrine Neoplasia Type 1 (MEN1)
Rajesh V. Thakker et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)
The same pocket in menin binds both MLL and JUND but has opposite effects on transcription
Jing Huang et al.
NATURE (2012)
Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia
Jolanta Grembecka et al.
NATURE CHEMICAL BIOLOGY (2012)
Reexpression of oncoprotein MafB in proliferative β-cells and Men1 insulinomas in mouse
J. Lu et al.
ONCOGENE (2012)
The Negative Feedback-Loop between the Oncomir Mir-24-1 and Menin Modulates the Men1 Tumorigenesis by Mimicking the Knudson's Second Hit
Ettore Luzi et al.
PLOS ONE (2012)
Genome-Wide Characterization of Menin-Dependent H3K4me3 Reveals a Specific Role for Menin in the Regulation of Genes Implicated in MEN1-Like Tumors
Sunita K. Agarwal et al.
PLOS ONE (2012)
Pasireotide (SOM230) is effective for the treatment of pancreatic neuroendocrine tumors (PNETs) in a multiple endocrine neoplasia type 1 (MEN1) conditional knockout mouse model
Thomas J. Quinn et al.
SURGERY (2012)
Suppression of Tumor Invasion and Metastasis by Concurrent Inhibition of c-Met and VEGF Signaling in Pancreatic Neuroendocrine Tumors
Barbara Sennino et al.
CANCER DISCOVERY (2012)
Gender-related differences in MEN1 lesion occurrence and diagnosis: a cohort study of 734 cases from the Groupe d'etude des Tumeurs Endocrines
P. Goudet et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2011)
Crystal Structure of Menin Reveals Binding Site for Mixed Lineage Leukemia (MLL) Protein
Marcelo J. Murai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Long-term results of surgery for pancreatic neuroendocrine neoplasms in patients with MEN1
Caroline L. Lopez et al.
LANGENBECKS ARCHIVES OF SURGERY (2011)
Sunitinib Malate for the Treatment of Pancreatic Neuroendocrine Tumors.
Eric Raymond et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
The Menin Tumor Suppressor Protein Is Phosphorylated in Response to DNA Damage
Joshua Francis et al.
PLOS ONE (2011)
Counterbalancing angiogenic regulatory factors control the rate of cancer progression and survival in a stage-specific manner
Liang Xie et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1
Wenchu Lin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors
Yuchen Jiao et al.
SCIENCE (2011)
Long-term follow-up of an 8-year-old boy with insulinoma as the first manifestation of a familial form of multiple endocrine neoplasia type 1
Helena Campos Fabbri et al.
ARQUIVOS BRASILEIROS DE ENDOCRINOLOGIA E METABOLOGIA (2010)
The role of germline AIP, MEN1, PRKAR1A, CDKN1B and CDKN2C mutations in causing pituitary adenomas in a large cohort of children, adolescents, and patients with genetic syndromes
C. A. Stratakis et al.
CLINICAL GENETICS (2010)
Multiple Endocrine Neoplasia Type 1 Deletion in Pancreatic α-Cells Leads to Development of Insulinomas in Mice
H. -C. Jennifer Shen et al.
ENDOCRINOLOGY (2010)
α Cell-Specific Men1 Ablation Triggers the Transdifferentiation of Glucagon-Expressing Cells and Insulinoma Development
Jieli Lu et al.
GASTROENTEROLOGY (2010)
Diagnostic Challenges Due to Phenocopies: Lessons from Multiple Endocrine Neoplasia Type1 (MEN1)
Jeremy J. O. Turner et al.
HUMAN MUTATION (2010)
Cell Division Cycle Protein 73 Homolog (CDC73) Mutations in the Hyperparathyroidism-Jaw Tumor Syndrome (HPT-JT) and Parathyroid Tumors
Paul J. Newey et al.
HUMAN MUTATION (2010)
Daily Oral Everolimus Activity in Patients With Metastatic Pancreatic Neuroendocrine Tumors After Failure of Cytotoxic Chemotherapy: A Phase II Trial
James C. Yao et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
Risk Factors and Causes of Death in MEN1 Disease. A GTE (Groupe d'Etude des Tumeurs Endocrines) Cohort Study Among 758 Patients
Pierre Goudet et al.
WORLD JOURNAL OF SURGERY (2010)
Clinical Use of Cinacalcet in MEN1 Hyperparathyroidism
V. J. Moyes et al.
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (2010)
The epidemiology and genetics of pituitary adenomas
Adrian F. Daly et al.
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2009)
Recapitulation of Pancreatic Neuroendocrine Tumors in Human Multiple Endocrine Neoplasia Type I Syndrome via Pdx1-Directed Inactivation of Men1
H. -C. Jennifer Shen et al.
CANCER RESEARCH (2009)
Multiple endocrine neoplasia type 1 (MEN1): its manifestations and effect of genetic screening on clinical outcome
C. R. C. Pieterman et al.
CLINICAL ENDOCRINOLOGY (2009)
Multiple endocrine neoplasia type 1 knockout mice develop parathyroid, pancreatic, pituitary and adrenal tumours with hypercalcaemia, hypophosphataemia and hypercorticosteronaemia
Brian Harding et al.
ENDOCRINE-RELATED CANCER (2009)
Multiple endocrine neoplasia type 1-associated thyrotropin-producing pituitary carcinoma: report of a probable de novo example
Bernd W. Scheithauer et al.
HUMAN PATHOLOGY (2009)
Rare Germline Mutations in Cyclin-Dependent Kinase Inhibitor Genes in Multiple Endocrine Neoplasia Type 1 and Related States
Sunita K. Agarwal et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2009)
Global Analysis of H3K4 Methylation Defines MLL Family Member Targets and Points to a Role for MLL1-Mediated H3K4 Methylation in the Regulation of Transcriptional Initiation by RNA Polymerase II
Pengfei Wang et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Linking DNA methylation and histone modification: patterns and paradigms
Howard Cedar et al.
NATURE REVIEWS GENETICS (2009)
Screening of Patients with Multiple Endocrine Neoplasia Type 1 (MEN-1): A Critical Analysis of Its Value
Jens Waldmann et al.
WORLD JOURNAL OF SURGERY (2009)
Thymic Neuroendocrine Tumors in Multiple Endocrine Neoplasia Type 1: A Comparative Study on 21 Cases Among a Series of 761 MEN1 from the GTE (Groupe des Tumeurs Endocrines)
Pierre Goudet et al.
WORLD JOURNAL OF SURGERY (2009)
Suberoylanilide hydroxamic acid (SAHA) induces growth arrest and apoptosis in pituitary adenoma cells
S. R. Sangeetha et al.
ENDOCRINE (2009)
Somatostatin analogues in the control of neuroendocrine tumours: efficacy and mechanisms
Simona Grozinsky-Glasberg et al.
ENDOCRINE-RELATED CANCER (2008)
Multiple endocrine neoplaslia type 1 (MEN 1): Analysis of 1336 mutations reported in the first decade following identification of the gene
Manuel C. Lemos et al.
HUMAN MUTATION (2008)
Ischemic Stroke as the Presenting Symptom of Primary Hyperparathyroidism Due to Multiple Endocrine Neoplasia Type 1
Naim Mitre et al.
JOURNAL OF PEDIATRICS (2008)
Familial isolated primary hyperparathyroidism caused by mutations of the MEN1 gene
Fadil M. Hannan et al.
NATURE CLINICAL PRACTICE ENDOCRINOLOGY & METABOLISM (2008)
Cell lineage-specific interactions between Men1 and Rb in neuroendocrine neoplasia
Andres Matoso et al.
CARCINOGENESIS (2008)
Age-related penetrance of endocrine tumours in multiple endocrine neoplasia type 1 (MEN1): a multicentre study of 258 gene carriers
Andreas Machens et al.
CLINICAL ENDOCRINOLOGY (2007)
Multiple endocrine neoplasia type 1 in Northern Finland;: clinical features and genotype-phenotype correlation
O. Vierimaa et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2007)
The impact of clinical and genetic screenings on the management of the multiple endocrine neoplasia type 1
Delmar Muniz Lourenco et al.
CLINICS (2007)
Germline CDKN1B/p27Kip1 mutation in multiple endocrine neoplasia
Marianthi Georgitsi et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)
Lack of augmentation of tumor spectrum or severity in dual heterozygous Men1 and Rb1 knockout mice
K. A. Loffler et al.
ONCOGENE (2007)
P18Ink4c, but not p27Kip1, collaborates with Men1 to suppress neuroendocrine organ tumors
Feng Bai et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Distribution of menin-occupied regions in chromatin specifies a broad role of menin in transcriptional regulation
Sunita K. Agarwal et al.
NEOPLASIA (2007)
Broad tumor spectrum in a mouse model of multiple endocrine neoplasia type 1
Kelly A. Loffler et al.
INTERNATIONAL JOURNAL OF CANCER (2007)
Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans
Natalia S. Pellegata et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Advances in the treatment of prolactinomas
Mary P. Gillam et al.
ENDOCRINE REVIEWS (2006)
Pancreatectomy in multiple endocrine neoplasia type 1-related gastrinomas and pancreatic endocrine neoplasias
Francesco Tonelli et al.
ANNALS OF SURGERY (2006)
Tumor suppressor menin: the essential role of nuclear localization signal domains in coordinating gene expression
P. La et al.
ONCOGENE (2006)
Mutation of tumor suppressor gene menl acutely enhances proliferation of pancreatic islet cells
Robert W. Schnepp et al.
CANCER RESEARCH (2006)
Is surgery beneficial for MEN1 patients with small (≤2 cm), nonfunctioning pancreaticoduodenal endocrine tumor?: An analysis of 65 patients from the GTE
F Triponez et al.
WORLD JOURNAL OF SURGERY (2006)
Microadenomatosis of the endocrine pancreas in patients with and without the multiple endocrine neoplasia type 1 syndrome
M Anlauf et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2006)
Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis
Peter C. Scacheri et al.
PLOS GENETICS (2006)
Epidemiology data on 108 MEN 1 patients from the GTE with isolated nonfunctioning tumors of the pancreas
F Triponez et al.
ANNALS OF SURGERY (2006)
Development of a histological pseudocapsule and its use as a surgical capsule in the excision of pituitary tumors
EH Oldfield et al.
JOURNAL OF NEUROSURGERY (2006)
The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis
A Yokoyama et al.
CELL (2005)
Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c
SK Karnik et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors
O Casanovas et al.
CANCER CELL (2005)
Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors
TA Milne et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Conditional inactivation of the Men1 gene leads to pancreatic and pituitary tumorigenesis but does not affect normal development of these tissues
CA Biondi et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Menin associates with a trithorax family histone methyltransferase complex and with the Hoxc8 locus
CM Hughes et al.
MOLECULAR CELL (2004)
Cushing's disease in childhood as the first manifestation of multiple endocrine neoplasia syndrome type 1
M Rix et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2004)
Effect of multiple endocrine neoplasia type 1 (MEN1) gene mutations on premature mortality in familial MEN1 syndrome with founder mutations
T Ebeling et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)
Homozygous loss of menin is well tolerated in liver, a tissue not affected in MEN1
PC Scacheri et al.
MAMMALIAN GENOME (2004)
Prevalence, characteristics and prognosis of MEN 1-associated glucagonomas, VIPomas, and somatostatinomas -: Study from the GTE (Groupe des Tumeurs Endocrines) registry
N Lévy-Bohbot et al.
GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE (2004)
Transcription factor JunD, deprived of menin, switches from growth suppressor to growth promoter
SK Agarwal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Heterozygous Men1 mutant mice develop a range of endocrine tumors mimicking multiple endocrine neoplasia type 1
P Bertolino et al.
MOLECULAR ENDOCRINOLOGY (2003)
Of mice and MEN1: Insulinomas in a conditional mouse knockout
JS Crabtree et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Genetic ablation of the tumor suppresor menin causes lethality at mid-gestation with defects in multiple organs
P Bertolino et al.
MECHANISMS OF DEVELOPMENT (2003)
Comparison of surgical results in patients with advanced and limited disease with multiple endocrine neoplasia type 1 and Zollinger-Ellison syndrome
JA Norton et al.
ANNALS OF SURGERY (2001)
Multiple leiomyomas of the esophagus, lung, and uterus in multiple endocrine neoplasia type 1
JL McKeeby et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)
A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors
JS Crabtree et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
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