Journal
DEVELOPMENT
Volume 143, Issue 13, Pages 2249-2260Publisher
COMPANY OF BIOLOGISTS LTD
DOI: 10.1242/dev.135616
Keywords
Anastomosis; Angiogenesis; Endothelial cells; Live imaging; Pruning; Sprouting; Vegf; Zebrafish
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Funding
- Kanton Basel-Stadt
- Swiss National Science Foundation [310030B_138651]
- Krebsliga Schweiz Foundation [KLS 3177-02-2013]
- Novartis Stiftung fur Medizinisch-Biologische Forschung [13A40]
- Kanton Basel-Land
- Swiss National Science Foundation (SNF) [310030B_138651] Funding Source: Swiss National Science Foundation (SNF)
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Vascular networks are formed and maintained through a multitude of angiogenic processes, such as sprouting, anastomosis and pruning. Only recently has it become possible to study the behavior of the endothelial cells that contribute to these networks at a single-cell level in vivo. This Review summarizes what is known about endothelial cell behavior during developmental angiogenesis, focusing on the morphogenetic changes that these cells undergo.
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