Related references
Note: Only part of the references are listed.Antisense oligonucleotides: the next frontier for treatment of neurological disorders
Carlo Rinaldi et al.
NATURE REVIEWS NEUROLOGY (2018)
Nuclear PTEN deficiency causes microcephaly with decreased neuronal soma size and increased seizure susceptibility
Atsushi Igarashi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition
Luye Qin et al.
NATURE NEUROSCIENCE (2018)
Nuclear Excluded Autism-Associated Phosphatase and Tensin Homolog Mutations Dysregulate Neuronal Growth
Catherine J. Fricano-Kugler et al.
BIOLOGICAL PSYCHIATRY (2018)
A molecular atlas of cell types and zonation in the brain vasculature
Michael Vanlandewijck et al.
NATURE (2018)
Antisense oligonucleotide therapy for spinocerebellar ataxia type 2
Daniel R. Scoles et al.
NATURE (2017)
PTEN: Local and Global Modulation of Neuronal Function in Health and Disease
Shira Knafo et al.
TRENDS IN NEUROSCIENCES (2017)
Neural transcriptome of constitutional Pten dysfunction in mice and its relevance to human idiopathic autism spectrum disorder
A. K. Tilot et al.
MOLECULAR PSYCHIATRY (2016)
Autistic-Like Traits and Cerebellar Dysfunction in Purkinje Cell PTEN Knock-Out Mice
Dario Cupolillo et al.
NEUROPSYCHOPHARMACOLOGY (2016)
Loss of Glycine Transporter 1 Causes a Subtype of Glycine Encephalopathy with Arthrogryposis and Mildly Elevated Cerebrospinal Fluid Glycine
Alina Kurolap et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2016)
Mutation in SLC6A9 encoding a glycine transporter causes a novel form of non-ketotic hyperglycinemia in humans
Majid Alfadhel et al.
HUMAN GENETICS (2016)
PTEN recruitment controls synaptic and cognitive function in Alzheimer's models
Shira Knafo et al.
NATURE NEUROSCIENCE (2016)
Characterization of GABAA receptor ligands with automated patch-clamp using human neurons derived from pluripotent stem cells
Nina Y. Yuan et al.
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS (2016)
Analysis of the brain mural cell transcriptome
Liqun He et al.
SCIENTIFIC REPORTS (2016)
NMDA receptor dysfunction in autism spectrum disorders
Eun-Jae Lee et al.
CURRENT OPINION IN PHARMACOLOGY (2015)
Hyperactivity of Newborn Pten Knock-out Neurons Results from Increased Excitatory Synaptic Drive
Michael R. Williams et al.
JOURNAL OF NEUROSCIENCE (2015)
HTSeq-a Python framework to work with high-throughput sequencing data
Simon Anders et al.
BIOINFORMATICS (2015)
Towards a therapy for Angelman syndrome by targeting a long non-coding RNA
Linyan Meng et al.
NATURE (2015)
Trimmomatic: a flexible trimmer for Illumina sequence data
Anthony M. Bolger et al.
BIOINFORMATICS (2014)
Nuclear trafficking of Pten after brain injury leads to neuron survival not death
Choo-Peng Goh et al.
EXPERIMENTAL NEUROLOGY (2014)
Pten haploinsufficient mice show broad brain overgrowth but selective impairments in autism-relevant behavioral tests
Amy E. Clipperton-Allen et al.
HUMAN MOLECULAR GENETICS (2014)
Detergent Induction of HEK 293A Cell Membrane Permeability Measured under Quiescent and Superfusion Conditions Using Whole Cell Patch Clamp
Sriram Vaidyanathan et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2014)
A polygenic burden of rare disruptive mutations in schizophrenia
Shaun M. Purcell et al.
NATURE (2014)
Capillary pericytes regulate cerebral blood flow in health and disease
Catherine N. Hall et al.
NATURE (2014)
Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior
Yang Zhan et al.
NATURE NEUROSCIENCE (2014)
Organization, control and function of extrasynaptic NMDA receptors
Thomas Papouin et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)
Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteins
Joaquin N. Lugo et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2014)
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
Michael I. Love et al.
GENOME BIOLOGY (2014)
Critical Role of Increased PTEN Nuclear Translocation in Excitotoxic and Ischemic Neuronal Injuries
Shu Zhang et al.
JOURNAL OF NEUROSCIENCE (2013)
Transporters of the blood-brain and blood-CSF interfaces in development and in the adult
Norman R. Saunders et al.
MOLECULAR ASPECTS OF MEDICINE (2013)
Deletion of PTEN produces deficits in conditioned fear and increases fragile X mental retardation protein
Joaquin N. Lugo et al.
LEARNING & MEMORY (2013)
Glycine transporters as novel therapeutic targets in schizophrenia, alcohol dependence and pain
Robert J. Harvey et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism
Koichi Takeuchi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Nuclear PTEN Controls DNA Repair and Sensitivity to Genotoxic Stress
C. Bassi et al.
SCIENCE (2013)
TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
Daehwan Kim et al.
GENOME BIOLOGY (2013)
Ion Channel Pharmacology Under Flow: Automation Via Well-Plate Microfluidics
C. Ian Spencer et al.
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2012)
The solute carrier 6 family of transporters
Stefan Broeer et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Thinking Outside the Synapse: Glycine at Extrasynaptic NMDA Receptors
John A. Gray et al.
CELL (2012)
Synaptic and Extrasynaptic NMDA Receptors Are Gated by Different Endogenous Coagonists
Thomas Papouin et al.
CELL (2012)
Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia
Jason Howitt et al.
JOURNAL OF CELL BIOLOGY (2012)
Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function
Hyejung Won et al.
NATURE (2012)
Mitochondrial Dysfunction in Pten Haplo-Insufficient Mice with Social Deficits and Repetitive Behavior: Interplay between Pten and p53
Eleonora Napoli et al.
PLOS ONE (2012)
IonFlux: A Microfluidic Patch Clamp System Evaluated with Human Ether-a-go-go Related Gene Channel Physiology and Pharmacology
Andrew P. Golden et al.
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2011)
Modelling schizophrenia using human induced pluripotent stem cells
Kristen J. Brennand et al.
NATURE (2011)
The Postsynaptic Organization of Synapses
Morgan Sheng et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)
PTEN is recruited to the postsynaptic terminal for NMDA receptor-dependent long-term depression
Sandra Jurado et al.
EMBO JOURNAL (2010)
Glial Glycine Transporter 1 Function Is Essential for Early Postnatal Survival but Dispensable in Adult Mice
Volker Eulenburg et al.
GLIA (2010)
Behavioural phenotyping assays for mouse models of autism
Jill L. Silverman et al.
NATURE REVIEWS NEUROSCIENCE (2010)
Comparative genomics of autism and schizophrenia
Bernard Crespi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Expression Profiling of the Solute Carrier Gene Family in the Mouse Brain
Amber Dahlin et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)
Sodium translocation by the iminoglycinuria associated imino transporter (SLC6A20)
Angelika Broeer et al.
MOLECULAR MEMBRANE BIOLOGY (2009)
The blood-brain and the blood-cerebrospinal fluid barriers: function and dysfunction
Britta Engelhardt et al.
SEMINARS IN IMMUNOPATHOLOGY (2009)
Glycine transport inhibitors and the treatment of schizophrenia
Daniel C. Javitt
BIOLOGICAL PSYCHIATRY (2008)
SIT1 is a betaine/proline transporter that is activated in mouse eggs after fertilization and functions until the 2-cell stage
Mohamed-Kheir Idris Anas et al.
DEVELOPMENT (2008)
Rescue of hippocampal LTP and learning deficits in a rat model of psychosis by inhibition of glycine transporter-1 (GlyT1)
Denise Manahan-Vaughan et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2008)
Retinal degeneration triggered by inactivation of PTEN in the retinal pigment epithelium
Jin Woo Kim et al.
GENES & DEVELOPMENT (2008)
Autism-like behavioral phenotypes in BTBR T+tf/J mice
H. G. McFarlane et al.
GENES BRAIN AND BEHAVIOR (2008)
The nuclear affairs of PTEN
Sarah M. Planchon et al.
JOURNAL OF CELL SCIENCE (2008)
Iminoglycinuria and hyperglycinuria are discrete human phenotypes resulting from complex mutations in proline and glycine transporters
Stefan Broeer et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
PTEN signaling in brain: neuropathology and tumorigenesis
R. Endersby et al.
ONCOGENE (2008)
Barriers in the brain: a renaissance?
Norman R. Saunders et al.
TRENDS IN NEUROSCIENCES (2008)
NHERFs, NEP, MAGUKs, and more: Interactions that regulate PTEN
Challice L. Bonifant et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2007)
Phosphorylation of β-catenin by AKT promotes β-catenin transcriptional activity
Dexing Fang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
UP inhibits LTD in the hippocampus via regulation of GSK3β
Stephane Peineau et al.
NEURON (2007)
Glycine transporter I inhibitor, N-methylglycine (Sarcosine), added to clozapine for the treatment of schizophrenia
Hsien-Yuan Lane et al.
BIOLOGICAL PSYCHIATRY (2006)
Pten regulates neuronal arborization and social interaction in mice
Chang-Hyuk Kwon et al.
NEURON (2006)
Phosphorylation of β-catenin by cyclic AMP-dependent protein kinase
S Taurin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling
Y Takahashi et al.
EMBO JOURNAL (2006)
Glycine transporters: essential regulators of synaptic transmission
H Betz et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2006)
Digging and marble burying in mice: simple methods for in vivo identification of biological impacts
Robert M. J. Deacon
NATURE PROTOCOLS (2006)
Reference data for cerebrospinal fluid and the utility of amino acid measurement for the diagnosis of inborn errors of metabolism
CM Jones et al.
ANNALS OF CLINICAL BIOCHEMISTRY (2006)
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Phosphorylation of β-catenin by cyclic AMP-dependent protein kinase stabilizes β-catenin through inhibition of its ubiquitination
S Hino et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Localization of the GLYT1 glycine transporter at glutamatergic synapses in the rat brain
B Cubelos et al.
CEREBRAL CORTEX (2005)
Molecular cloning of the mouse IMINO system:: an Na+- and Cl--dependent proline transporter
S Kowalczuk et al.
BIOCHEMICAL JOURNAL (2005)
Identification of mammalian proline transporter SIT1 ( SLC6A20) with characteristics of classical system imino
H Takanaga et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Enhancement of the NMDA receptor function by reduction of glycine transporter-1 expression
L Gabernet et al.
NEUROSCIENCE LETTERS (2005)
Glycine transporter I inhibitor, N-methylglycine (Sarcosine), added to antipsychotics for the treatment of schizophrenia
GC Tsai et al.
BIOLOGICAL PSYCHIATRY (2004)
Expanded characterization of the social interaction abnormalities in mice lacking Dcl1
JM Long et al.
GENES BRAIN AND BEHAVIOR (2004)
Gene knockout of glycine transporter 1: Characterization of the behavioral phenotype
G Tsai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Glycine transporter type 1 blockade changes NMDA receptor-mediated responses and LTP in hippocampal CA1 pyramidal cells by altering extracellular glycine levels
M Martina et al.
JOURNAL OF PHYSIOLOGY-LONDON (2004)
New aspects of the blood-brain barrier transporters; Its physiological roles in the central nervous system
S Ohtsuki
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2004)
Automated apparatus for quantitation of social approach behaviors in mice
JJ Nadler et al.
GENES BRAIN AND BEHAVIOR (2004)
Inactivation of the glycine transporter 1 gene discloses vital role of glial glycine uptake in Glycinergic inhibition
J Gomeza et al.
NEURON (2003)
Glycine tranporter-1 blockade potentiates NMDA-mediated responses in rat prefrontal cortical neurons in vitro and in vivo
L Chen et al.
JOURNAL OF NEUROPHYSIOLOGY (2003)
beta-catenin is critical for dendritic morphogenesis
X Yu et al.
NATURE NEUROSCIENCE (2003)
Comparative human/murine sequence analysis of the common eliminated region 1 from human 3p21.3
H Kiss et al.
MAMMALIAN GENOME (2002)
ATA2 is predominantly expressed as system A at the blood-brain barrier and acts as brain-to-blood efflux transport for L-proline
H Takanaga et al.
MOLECULAR PHARMACOLOGY (2002)
Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease
SA Backman et al.
NATURE GENETICS (2001)
Dendritic spines: Structure, dynamics and regulation
H Hering et al.
NATURE REVIEWS NEUROSCIENCE (2001)
Pharmacological assessment of the role of the glycine transporter GlyT-1 in mediating high-affinity glycine uptake by rat cerebral cortex and cerebellum synaptosomes
HJ Herdon et al.
NEUROPHARMACOLOGY (2001)
Subunit-specific rules governing AMPA receptor trafficking to synapses in hippocampal pyramidal neurons
SH Shi et al.
CELL (2001)
T cell-specific loss of Pten leads to defects in central and peripheral tolerance
A Suzuki et al.
IMMUNITY (2001)
PDZ domains and the organization of supramolecular complexes
M Sheng et al.
ANNUAL REVIEW OF NEUROSCIENCE (2001)
Phosphorylation of the PTEN tail regulates protein stability and function
F Vazquez et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity
HK Lee et al.
NATURE (2000)
D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor
JP Mothet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2
XY Wu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Driving AMPA receptors into synapses by LTP and CaMKII: Requirement for GluR1 and PDZ domain interaction
Y Hayashi et al.
SCIENCE (2000)