Journal
EMBO JOURNAL
Volume 39, Issue 24, Pages -Publisher
WILEY
DOI: 10.15252/embj.2020107326
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Funding
- MRC [MC_UU_00015/7] Funding Source: UKRI
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Mitochondria are dynamic organelles adapting their morphology by cycles of fission and fusion events to control cellular homeostasis. In this issue of The EMBO Journal, Murata and colleagues (2020) show that lack of mitochondrial division leads to safeguard mechanisms, induced by transient mitochondrial membrane depolarization and activation of the metalloprotease OMA1, to prevent extreme mitochondrial fusion and to maintain optimal mitochondrial bioenergetics.
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