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A treatise on Organophosphate pesticide pollution: Current strategies and advancements in their environmental degradation and elimination

Journal

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
Volume 207, Issue -, Pages -

Publisher

ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ecoenv.2020.111483

Keywords

Organophosphate pesticide; Acetylcholinesterase; Toxicology; Abiotic degradation; Biotic degradation

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Pesticides have been widely used in agriculture for pest control, with organophosphate pesticides being one of the most commonly used types. These pesticides cause irreversible inhibition of the AChE enzyme in living beings, leading to respiratory and neuromuscular impairments. The residues of organophosphate pesticides pose a threat to the environment and human health, with research focusing on the toxicological effects and methods of detection and degradation.
Pesticides have been used in the field of agriculture ever since their role in protection of crops from pests which include four different categories namely insects, mites, rodents and animals has been identified. Organophos-phate pesticides are one of the most extensively applied insecticides in the field of agriculture such that around 40% of all the pesticides that are produced and used commercially belong to this category. The main toxicological effect of these pesticides when exposed to a living being encompasses the irremediable inhibition of the acetylcholinesterase (AChE) enzyme which is involved in the neurotransmission of signals and hence its inhibition causes impairment of the respiratory tract and neuromuscular transmission. Apart from being used as a pesticide, organophosphates have also been applied as herbicides to some extent. The residues of these highly toxic chemicals have found route into the underground water system by seeping into the ground, in rivers where the agricultural run off water is disposed, and in the air when sprayed on the crops hence posing a threat to all the living strata exposed to these chemicals in various ways which are discussed further. Many significant studies have been carried out in order to evaluate the health risks associated with these pesticides which commonly include acute neurological disorders. This review emphasizes on the toxicological effects of organophosphate pesticides and the recent methods of detection that are used to identify trace amounts of organophosphate pesticides along with strategies which are used for their degradation.

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