Journal
DEVELOPMENT
Volume 143, Issue 8, Pages 1234-1241Publisher
COMPANY OF BIOLOGISTS LTD
DOI: 10.1242/dev.133298
Keywords
Bifunctional RNA; CncRNAs; Coding RNA; Development; Non-coding RNA; Regulatory RNA
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Funding
- Warwick Medical School
- Biotechnology and Biological Sciences Research Council
- European Molecular Biology Laboratory
- BBSRC [BB/L007525/1] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/L007525/1] Funding Source: researchfish
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RNAs are known to regulate diverse biological processes, either as protein-encoding molecules or as non-coding RNAs. However, a third class that comprises RNAs endowed with both protein coding and non-coding functions has recently emerged. Such bi-functional 'coding and non-coding RNAs' (cncRNAs) have been shown to play important roles in distinct developmental processes in plants and animals. Here, we discuss key examples of cncRNAs and review their roles, regulation and mechanisms of action during development.
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