Journal
CURRENT OPINION IN PLANT BIOLOGY
Volume 58, Issue -, Pages 60-68Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.pbi.2020.10.006
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Funding
- USDA National Institute of Food and Agriculture [CA-B-PLB-0243-H]
- University of California at Berkeley
- Innovative Genomics Institute (IGI)
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Nuclear pore complexes (NPC) are highly conserved mega protein complexes that penetrate the double-layered nuclear membrane and form channels to allow bi-directional transport of macromolecules between the nucleus and the cytosol. Non-passive nucleocytoplasmic transport also requires nuclear transport receptors (NTR), which bind cargo molecules and shuttle them across the NPC. The NPC and NTRs constitute two fundamental layers of regulatory mechanisms that together determine the selective nuclear translocation of signal molecules and play essential roles in activating the precise response of a cell to environmental stimuli. Here we discuss recent findings in the NPC made by advanced structural biology approaches, and dissect distinct functions of different NPC components and NTRs in plants' responses to various biotic and abiotic stresses.
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