Journal
CURRENT BIOLOGY
Volume 30, Issue 24, Pages R1476-R1478Publisher
CELL PRESS
DOI: 10.1016/j.cub.2020.09.047
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Funding
- NIGMS NIH HHS [R35 GM131753] Funding Source: Medline
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An investigation of how mitotic spindle size scales with cell size in early zebrafish embryos reveals fundamental principles of spindle organization. Spindle size depends primarily on microtubule number, which is regulated by a reaction-diffusion system when cells are large, and by signals from the plasma membrane when they are small.
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