Journal
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
Volume 62, Issue 10, Pages 2673-2682Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/10408398.2020.1857331
Keywords
Protein; bioactive peptides; antidiabetic activity; cereals; legumes
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This article reviews the current biological activity of protein derivatives and peptides isolated from cereals, pseudocereals, and legumes on therapeutic markers related to type 2 diabetes mellitus, highlighting their potential as a pharmacological treatment.
Proteins and peptides are fundamental components of the cereals, pseudocereals, and legumes, giving them numerous health-beneficial properties. Previous studies have demonstrated that these molecules exerted effects on current therapeutic targets related to type 2 diabetes mellitus, such as incretin hormones (responsible for appetite suppression), dipeptidyl peptidase IV (an enzyme involved in the inactivation and degradation of the incretin hormones), and glucose transporters (molecules that transport glucose in or out of cells). Therefore, this review presents the current biological activity of protein derivatives and peptides isolated from cereals, pseudocereals, and legumes on these therapeutic markers, highlighting their potential as a possible pharmacological treatment for type 2 diabetes mellitus.
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