Effect of deep transfer and multi-task learning on sperm abnormality detection

Analyzing the abnormality of morphological characteristics of male human sperm has been studied for a long time mainly because it has many implications on the male infertility problem, which accounts for approximately half of the infertility problems in the world. Yet, detecting such abnormalities by embryologists has several downsides. To clarify, analyzing sperms through visual inspection of an expert embryologist is a highly subjective and biased process. Furthermore, it takes much time for a specialist to make a diagnosis. Hence, in this paper, we proposed two deep learning algorithms that are able to automate this process. The first algorithm uses a network-based deep transfer learning approach, while the second technique, named Deep Multi-task Transfer Learning (DMTL), employs a novel combination of network-based deep transfer learning and multi-task learning to classify sperm's head, vacuole, and acrosome as either normal or abnormal. This DMTL technique is capable of classifying all the aforementioned parts of the sperm in a single prediction. Moreover, this is the first time that the concept of multi-task learning has been introduced to the field of Sperm Morphology Analysis (SMA). To benchmark our algorithms, we employed a freely-available SMA dataset named MHSMA. During our experiments, our algorithms reached the state-of-the-art results on the accuracy, precision, and f0.5, as well as other important metrics, such as the Matthews Correlation Coefficient on one, two, or all three labels. Notably, our algorithms increased the accuracy of the head, acrosome, and vacuole by 6.66%, 3.00%, and 1.33%, and reached the accuracy of 84.00%, 80.66%, and 94.00% on these labels, respectively. Consequently, our algorithms can be used in health institutions, such as fertility clinics, with further recommendations to practically improve the performance of our algorithms.

Automated summary

This paper proposed two deep learning algorithms for analyzing abnormal male human sperm morphology, one using a deep transfer learning approach, and the other utilizing a deep multi-task transfer learning method. These algorithms demonstrated state-of-the-art results in experiments, marking a significant advancement in the field of sperm morphology analysis.