4.1 Article

Biochemical Pathways and Modeling

Journal

CLINICAL OBSTETRICS AND GYNECOLOGY
Volume 64, Issue 1, Pages 12-19

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/GRF.0000000000000583

Keywords

PCOS; biochemical pathways; insulin resistance; hyperandrogenemia

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The exact etiology of the biochemical changes and symptoms in PCOS remains unknown, with genetics, lifestyle, and hormonal abnormalities all playing a role. This article delves into the dysregulation of multiple biochemical pathways in PCOS and their impact on female physiology.
The precise etiology of the biochemical changes and the resulting constellation of symptoms seen in polycystic ovary syndrome (PCOS) has remained a mystery. Despite advances in our knowledge, the pathogenesis and alterations in the biochemical pathways underlying this disease are still not fully understood. PCOS is a multifactorial syndrome where a combination of genetics, lifestyle, and hormone abnormalities all play an intertwining role. This article will provide an in-depth look at the multitude of biochemical pathways that are dysregulated in PCOS and their relation to alterations in female physiology.

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