4.1 Article

In Vitro Fertilization for Polycystic Ovarian Syndrome

Journal

CLINICAL OBSTETRICS AND GYNECOLOGY
Volume 64, Issue 1, Pages 39-47

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/GRF.0000000000000561

Keywords

infertility; in vitro fertilization; polycystic ovarian syndrome; ovarian hyperstimulation syndrome; in vitro maturation

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In vitro fertilization is suitable for PCOS patients, especially those who have not responded to ovulation induction agents or are considered high-risk for multiple gestations. Choosing the right treatment protocol and medication dosage, as well as close monitoring, can reduce the risk of ovarian hyperstimulation syndrome during treatment.
In vitro fertilization is indicated for infertile women with polycystic ovarian syndrome (PCOS) after unsuccessful treatment with ovulation induction agents or in women deemed high-risk of multiple gestations who are ideal candidates for single embryo transfers. PCOS patients are at increased risk of ovarian hyperstimulation syndrome; therefore, attention should be made in the choice of in vitro fertilization treatment protocol, dose of gonadotropin utilized, and regimen to achieve final oocyte maturation. Adopting these strategies in addition to close monitoring may significantly reduce the ovarian hyperstimulation syndrome risk. Future developments may improve pregnancy outcomes and decrease complications in PCOS women undergoing fertility treatment.

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