Altered Biodistribution of 68Ga-DOTATOC

Ga-68-DOTATOC PET/CT of a patient with metastatic neuroendocrine tumor reveals an abnormal biodistribution of the tracer with a vascular binding and a very low fixation on the known lesions despite the temporary discontinuation of cold somatostatin analogs. A possible interaction with a high intake of turmeric may be suspected by inhibition of hepatic uptake process.

Automated summary

In this case, Ga-68-DOTATOC PET/CT imaging revealed abnormal biodistribution of the tracer with vascular binding and very low fixation on known lesions, possibly due to a high intake of turmeric inhibiting hepatic uptake process.