Related references
Note: Only part of the references are listed.Green synthesis and biological evaluation of 6-substituted-2-(2-hydroxy/methoxy phenyl)benzothiazole derivatives as potential antioxidant, antibacterial and antitumor agents
Livio Racane et al.
BIOORGANIC CHEMISTRY (2020)
The C-H activated controlled mono- and di-olefination of arenes in ionic liquids at room temperature
Kaifeng Du et al.
RSC ADVANCES (2020)
The next level in chemical space navigation: going far beyond enumerable compound libraries
Torsten Hoffmann et al.
DRUG DISCOVERY TODAY (2019)
Weinreb Amides as Directing Groups for Transition Metal-Catalyzed C-H Functionalizations
Jagadeesh Kalepu et al.
MOLECULES (2019)
Tafamidis: A Review in Transthyretin Amyloidosis with Polyneuropathy
Yvette N. Lamb et al.
DRUGS (2019)
Ruthenium-Catalyzed Enantioselective C-H Functionalization: A Practical Access to Optically Active Indoline Derivatives
Zhong-Yuan Li et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)
Ruthenium(II)-Catalyzed C-H Alkenylation of Quinones: Diversity-Oriented Strategy for Trypanocidal Compounds
Gleiston G. Dias et al.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2019)
Site-selective Ru-catalyzed C-H bond alkenylation with biologically relevant isoindolinones: a case of catalyst performance controlled by subtle stereo-electronic effects of the weak directing group
Yu-Chao Yuan et al.
CATALYSIS SCIENCE & TECHNOLOGY (2019)
Understanding electronic effects on carboxylate-assisted C-H activation at ruthenium: the importance of kinetic and thermodynamic control
Raed A. Alharis et al.
FARADAY DISCUSSIONS (2019)
Transient-Ligand-Enabled ortho-Arylation of Five-Membered Heterocycles: Facile Access to Mechanochromic Materials
Bijin Li et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)
C-H Functionalisation for Hydrogen Isotope Exchange
Jens Atzrodt et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)
Late stage modifications of P-containing ligands using transition-metal-catalysed C-H bond functionalisation
Zhuan Zhang et al.
CHEMICAL COMMUNICATIONS (2018)
Weakly-coordinating N-oxide and carbonyl groups for metal-catalyzed C-H activation: the case of A-ring functionalization
Eufranio N. da Silva Junior et al.
CHEMICAL COMMUNICATIONS (2018)
Access to the meta position of arenes through transition metal catalysed C-H bond functionalisation: a focus on metals other than palladium
Madalina T. Mihai et al.
CHEMICAL SOCIETY REVIEWS (2018)
Benzo[d]thiazole-2-carbanilides as new anti-TB chemotypes: Design, synthesis, biological evaluation, and structure-activity relationship
Tejas M. Dhameliya et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Controlled mono-olefination versus diolefination of arenes via C-H activation in water: a key role of catalysts
Hailong Zhang et al.
GREEN CHEMISTRY (2018)
Pd-Catalyzed, ortho C-H Methylation and Fluorination of Benzaldehydes Using Orthanilic Acids as Transient Directing Groups
Xiao-Yang Chen et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)
Cyclometallated ruthenium catalyst enables late-stage directed arylation of pharmaceuticals
Marco Simonetti et al.
NATURE CHEMISTRY (2018)
Ligand-free, palladacycle-facilitated Suzuki coupling of hindered 2-arylbenzothiazole derivatives yields potent and selective COX-2 inhibitors
Mohamed S. A. Elsayed et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2018)
Transient imines as 'next generation' directing groups for the catalytic functionalisation of C-H bonds in a single operation
Sahra St John-Campbell et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2018)
sp3 C-H activation via exo-type directing groups
Yan Xu et al.
CHEMICAL SCIENCE (2018)
Combining transition metals and transient directing groups for C-H functionalizations
Trisha Bhattacharya et al.
RSC ADVANCES (2018)
Transient Directing Groups for Transformative C-H Activation by Synergistic Metal Catalysis
Parthasarathy Gandeepan et al.
CHEM (2018)
A comprehensive overview of directing groups applied in metal-catalysed C-H functionalisation chemistry
Carlo Sambiagio et al.
CHEMICAL SOCIETY REVIEWS (2018)
Mechanistic view of Ru-catalyzed C-H bond activation and functionalization: computational advances
Chunhui Shan et al.
CHEMICAL SOCIETY REVIEWS (2018)
Expanding the medicinal chemistry synthetic toolbox
Jonas Bostrom et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
Cross-Dehydrogenative Coupling of Heterocyclic Scaffolds with Unfunctionalized Aroyl Surrogates by Palladium(II) Catalyzed C(sp2)-H Aroylation through Organocatalytic Dioxygen Activation
Bhavin V. Pipaliya et al.
JOURNAL OF ORGANIC CHEMISTRY (2017)
Diverse ortho-C(sp2)-H Functionalization of Benzaldehydes Using Transient Directing Groups
Xi-Hai Liu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)
Ligand-accelerated non-directed C-H functionalization of arenes
Peng Wang et al.
NATURE (2017)
Ligand-Assisted Heteroaryl C(sp2)-H Bond Activation by a Cationic Ruthenium(II) Complex for Alkenylation of Heteroarenes with Alkynes Directed by Biorelevant Heterocycles
Bhavin V. Pipaliya et al.
CHEMCATCHEM (2017)
Mechanism of Rhodium-Catalyzed C-H Functionalization: Advances in Theoretical Investigation
Xiaotian Qi et al.
ACCOUNTS OF CHEMICAL RESEARCH (2017)
Recent advances in the ruthenium(II)-catalyzed chelation-assisted C-H olefination of substituted aromatics, alkenes and heteroaromatics with alkenes via the deprotonation pathway
Rajendran Manikandan et al.
CHEMICAL COMMUNICATIONS (2017)
Computational Studies of Carboxylate-Assisted C-H Activation and Functionalization at Group 8-10 Transition Metal Centers
David L. Davies et al.
CHEMICAL REVIEWS (2017)
Ruthenium-Catalyzed C-H Activation and Coupling Reactions in Organic Synthesis
Arpad Molnar et al.
CURRENT ORGANIC CHEMISTRY (2016)
Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?
Dean G. Brow et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Synchronous double C-N bond formation via C-H activation for a novel synthetic route to phenazine
Kapileswar Seth et al.
CHEMICAL COMMUNICATIONS (2016)
Synthesis of o-Alkenylated 2-Arylbenzoxazoles via Rh-Catalyzed Oxidative Olefination of 2-Arylbenzoxazoles: Scope Investigation, Structural Features, and Mechanism Studies
Quan Zhou et al.
JOURNAL OF ORGANIC CHEMISTRY (2016)
Recent Progress on Copper-Mediated Directing-Group-Assisted C(sp2)-H Activation
Ming Shang et al.
SYNTHESIS-STUTTGART (2016)
Ruthenium(II)-Catalyzed C-H Functionalization Using the Oxazolidinone Heterocycle as a Weakly Coordinating Directing Group: Experimental and Computational Insights
Jamie A. Leitch et al.
ACS CATALYSIS (2016)
The palladium and copper contrast: a twist to products of different chemotypes and altered mechanistic pathways
Kapileswar Seth et al.
CATALYSIS SCIENCE & TECHNOLOGY (2016)
Substrate Activation Strategies in Rhodium(III)-Catalyzed Selective Functionalization of Arenes
Guoyong Song et al.
ACCOUNTS OF CHEMICAL RESEARCH (2015)
Palladium catalyzed Csp2-H activation for direct aryl hydroxylation: the unprecedented role of 1,4-dioxane as a source of hydroxyl radicals
Kapileswar Seth et al.
CHEMICAL COMMUNICATIONS (2015)
Functionalization of C-H Bonds via Metal-Catalyzed Desulfitative Coupling: An Alternative Tool for Access to Aryl- or Alkyl-Substituted (Hetero)arenes
Kedong Yuan et al.
ACS CATALYSIS (2015)
Transition metal-catalyzed C-H bond functionalizations by the use of diverse directing groups
Zhengkai Chen et al.
ORGANIC CHEMISTRY FRONTIERS (2015)
Weakly Coordinating Directing Groups for Ruthenium(II)-Catalyzed C-H Activation
Suman De Sarkar et al.
ADVANCED SYNTHESIS & CATALYSIS (2014)
The Cross-Dehydrogenative Coupling of Csp3-H Bonds: A Versatile Strategy for C-C Bond Formations
Simon A. Girard et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)
Arene C-H functionalisation using a removable/modifiable or a traceless directing group strategy
Fengzhi Zhang et al.
CHEMICAL SOCIETY REVIEWS (2014)
Towards Ideal Synthesis: Alkenylation of Aryl C-H Bonds by a Fujiwara-Moritani Reaction
Lihong Zhou et al.
CHEMISTRY-A EUROPEAN JOURNAL (2014)
Tafamidis: A Review of Its Use in Familial Amyloid Polyneuropathy
Lesley J. Scott
DRUGS (2014)
Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among US FDA Approved Pharmaceuticals
Edon Vitaku et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Cooperative Catalysis by Palladium-Nickel Binary Nanocluster for Suzuki-Miyaura Reaction of Ortho-Heterocycle-Tethered Sterically Hindered Aryl Bromides
Kapileswar Seth et al.
ORGANIC LETTERS (2014)
2-(2-Arylphenyl)benzoxazole As a Novel Anti-Inflammatory Scaffold: Synthesis and Biological Evaluation
Kapileswar Seth et al.
ACS MEDICINAL CHEMISTRY LETTERS (2014)
Sustainable Practices in Medicinal Chemistry: Current State and Future Directions
Marian C. Bryan et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Exploring Chemical Space for Drug Discovery Using the Chemical Universe Database
Jean-Louis Reymond et al.
ACS CHEMICAL NEUROSCIENCE (2012)
Beyond Directing Groups: Transition-Metal-Catalyzed C-H Activation of Simple Arenes
Nadine Kuhl et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)
Synthesis and structure-activity relationship of aminopyridines with substituted benzoxazoles as c-Met kinase inhibitors
Jongkook Lee et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Ruthenium(II)-Catalyzed C-H Bond Activation and Functionalization
Percia Beatrice Arockiam et al.
CHEMICAL REVIEWS (2012)
Ru/Ag-Catalyzed Oxidative Alkenylation of Benzamides and Phenylazoles through Regioselective C-H Bond Cleavage
Yuto Hashimoto et al.
CHEMISTRY LETTERS (2012)
Tafamidis
Gerard Said et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
Removable Directing Groups in Organic Synthesis and Catalysis
Geraldine Rousseau et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)
Surfactant mediated oxygen reuptake in water for green aerobic oxidation: mass-spectrometric determination of discrete intermediates to correlate oxygen uptake with oxidation efficiency
Naisargee Parikh et al.
CHEMICAL COMMUNICATIONS (2011)
Recent advances in the transition metal-catalyzed twofold oxidative C-H bond activation strategy for C-C and C-N bond formation
Seung Hwan Cho et al.
CHEMICAL SOCIETY REVIEWS (2011)
The Medicinal Chemist's Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates
Stephen D. Roughley et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Divergent C-H Functionalizations Directed by Sulfonamide Pharmacophores: Late-Stage Diversification as a Tool for Drug Discovery
Hui-Xiong Dai et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Factors Determining the Selection of Organic Reactions by Medicinal Chemists and the Use of These Reactions in Arrays (Small Focused Libraries)
Tony W. J. Cooper et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)
Structure-Activity Relationships of Diverse Oxazolidinones for Linezolid-Resistant Staphylococcus aureus Strains Possessing the cfr Methyltransferase Gene or Ribosomal Mutations
Jeffrey B. Locke et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
Supramolecular Assemblies in Ionic Liquid Catalysis for Aza-Michael Reaction
Sudipta Raha Roy et al.
ORGANIC LETTERS (2010)
Chemical space as a source for new drugs
Jean-Louis Reymond et al.
MEDCHEMCOMM (2010)
Transition-Metal-Catalyzed Direct Arylation of (Hetero)Arenes by C-H Bond Cleavage
Lutz Ackermann et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)
Caboxamycin, a new antibiotic of the benzoxazole family produced by the deep-sea strain Streptomyces sp NTK 937
Claudia Hohmann et al.
JOURNAL OF ANTIBIOTICS (2009)
One-Pot Synthesis of 2-Substituted Benzoxazoles Directly from Carboxylic Acids
Dinesh Kumar et al.
AUSTRALIAN JOURNAL OF CHEMISTRY (2008)
Green chemistry tools to influence a medicinal chemistry and research chemistry based organisation
Kim Alfonsi et al.
GREEN CHEMISTRY (2008)
Key green chemistry research areas - a perspective from pharmaceutical manufacturers
David J. C. Constable et al.
GREEN CHEMISTRY (2007)
Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide (BAY 59-7939):: An oral, direct factor Xa inhibitor
S Roehrig et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)