Dumbbell-Shaped 2,2′-Bipyridines: Controlled Metal Monochelation and Application to Ni-Catalyzed Cross-Couplings

Dumbbell-shaped bipyridines, featuring distal steric effects of bipyridine C5- and C5'-triarylmethyl substituents, allowed controlled monochelation to transition metals. These newly synthesized ligands showed improved ligand performance compared to conventional bipyridine ligands in the Ni-catalyzed cross-electrophile coupling and the Ni/photoredox-synergistically catalyzed decarboxylative coupling. More information can be found in the Communication by T. Iwai, M. Sawamura, et al. (DOI: 10.1002/chem.202004053).

Automated summary

The newly synthesized dumbbell-shaped bipyridines with distal steric effects of bipyridine C5- and C5'-triarylmethyl substituents showed improved performance in nickel-catalyzed reactions compared to conventional ligands; these ligands are characterized by their molecular shape and distal steric effects.