Flash Chemistry Makes Impossible Organolithium Chemistry Possible

Organolithium reagents are often too unstable to use due to being highly reactive. This limits their application in organic synthesis. This review highlights our approach to various synthetic reactions mediated by organolithium reagents based on flash chemistry conducted in flow reactors, especially utilizing space-integration of the flow reactions.

Automated summary

This review showcases our approach to various synthetic reactions mediated by organolithium reagents based on flash chemistry conducted in flow reactors, particularly utilizing space-integration of the flow reactions.