Journal
DERMATOLOGY
Volume 232, Issue 4, Pages 478-483Publisher
KARGER
DOI: 10.1159/000447356
Keywords
Solar lentigines; Combination therapy; Pidobenzone 4%; CO2 laser; Cryotherapy
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Background/Objective: This study aims at the evaluation of the efficacy and safety of a combination therapy based on pidobenzone 4% and fractional CO2 laser or cryotherapy in the treatment of solar lentigines and the prevention of eventual posttreatment hyperchromia. Methods: Efficacy was clinically evaluated by grading the pigmentation level with the Skin Tone Color Scale (STCS), and by grading patients' impression through a Visual Analog Scale (VAS). Results: Our study shows that the associated treatment was safe and that it improves the therapeutic results on solar lentigines and prevents postiatrogenic hyperpigmentation compared with physical therapy alone. Conclusion: The combination of cryotherapy and pidobenzone 4% has been found to be the most useful treatment. (C) 2016 S. Karger AG, Basel
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