Related references
Note: Only part of the references are listed.A characterization of Gaucher iPS-derived astrocytes: Potential implications for Parkinson's disease
Elma Aflaki et al.
NEUROBIOLOGY OF DISEASE (2020)
Generation of homogeneous midbrain organoids with in vivo-like cellular composition facilitates neurotoxin-based Parkinson's disease modeling
Tae Hwan Kwak et al.
STEM CELLS (2020)
Human iPSC-derived mature microglia retain their identity and functionally integrate in the chimeric mouse brain
Ranjie Xu et al.
NATURE COMMUNICATIONS (2020)
Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease
Julien Bryois et al.
NATURE GENETICS (2020)
CD49f Is a Novel Marker of Functional and Reactive Human iPSC-Derived Astrocytes
Lilianne Barbar et al.
NEURON (2020)
G2019s LRRK2 promotes mitochondrial fission and increases TNFα-mediated neuroinflammation responses
Dong Hwan Ho et al.
ANIMAL CELLS AND SYSTEMS (2019)
NFIA is a gliogenic switch enabling rapid derivation of functional human astrocytes from pluripotent stem cells
Jason Tchieu et al.
NATURE BIOTECHNOLOGY (2019)
Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures
Rebecca M. Marton et al.
NATURE NEUROSCIENCE (2019)
Modeling G2019S-LRRK2 Sporadic Parkinson's Disease in 3D Midbrain Organoids
Hongwon Kim et al.
STEM CELL REPORTS (2019)
Pluripotent Stem Cell-Derived Cerebral Organoids Reveal Human Oligodendrogenesis with Dorsal and Ventral Origins
Hyosung Kim et al.
STEM CELL REPORTS (2019)
Human iPSC-Derived Blood-Brain Barrier Chips Enable Disease Modeling and Personalized Medicine Applications
Gad D. Vatine et al.
CELL STEM CELL (2019)
CRISPR/Cas9-mediated generation of a tyrosine hydroxylase reporter iPSC line for live imaging and isolation of dopaminergic neurons
Carles Calatayud et al.
SCIENTIFIC REPORTS (2019)
RNA sequencing reveals MMP2 and TGFB1 downregulation in LRRK2 G2019S Parkinson's iPSC-derived astrocytes
Heather D. E. Booth et al.
NEUROBIOLOGY OF DISEASE (2019)
Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes
Charmaine Lang et al.
CELL STEM CELL (2019)
Patient-Specific iPSC-Derived Astrocytes Contribute to Non-Cell-Autonomous Neurodegeneration in Parkinson's Disease
Angelique di Domenico et al.
STEM CELL REPORTS (2019)
Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson's disease heritability
Regina H. Reynolds et al.
NPJ PARKINSONS DISEASE (2019)
Modeling Parkinson's disease in midbrain-like organoids
Lisa M. Smits et al.
NPJ PARKINSONS DISEASE (2019)
Alpha-synuclein delays mitophagy and targeting Miro rescues neuron loss in Parkinson's models
Atossa Shaltouki et al.
ACTA NEUROPATHOLOGICA (2018)
Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease
Annika Sommer et al.
CELL STEM CELL (2018)
An in vivo model of functional and vascularized human brain organoids
Abed AlFatah Mansour et al.
NATURE BIOTECHNOLOGY (2018)
Normal aging induces A1-like astrocyte reactivity
Laura E. Clarke et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Human Cortex Spheroid with a Functional Blood Brain Barrier for High-Throughput Neurotoxicity Screening and Disease Modeling
Goodwell Nzou et al.
SCIENTIFIC REPORTS (2018)
Astrocytes Attenuate Mitochondrial Dysfunctions in Human Dopaminergic Neurons Derived from iPSC
Fang Du et al.
STEM CELL REPORTS (2018)
Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination
Zita Hubler et al.
NATURE (2018)
Rapid and efficient induction of functional astrocytes from human pluripotent stem cells
Isaac Canals et al.
NATURE METHODS (2018)
Induction of myelinating oligodendrocytes in human cortical spheroids
Mayur Madhavan et al.
NATURE METHODS (2018)
In situ immune response and mechanisms of cell damage in central nervous system of fatal cases microcephaly by Zika virus
Raimunda S. S. Azevedo et al.
SCIENTIFIC REPORTS (2018)
Fast Generation of Functional Subtype Astrocytes from Human Pluripotent Stem Cells
Xiang Li et al.
STEM CELL REPORTS (2018)
Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice
Richard Gordon et al.
SCIENCE TRANSLATIONAL MEDICINE (2018)
Microglia innately develop within cerebral organoids
Paul R. Ormel et al.
NATURE COMMUNICATIONS (2018)
Human Induced Pluripotent Stem Cell-Derived Astrocytes Are Differentially Activated by Multiple Sclerosis-Associated Cytokines
Sylvain Perriot et al.
STEM CELL REPORTS (2018)
Alpha-synuclein induces the unfolded protein response in Parkinson's disease SNCA triplication iPSC-derived neurons
Sabrina M. Heman-Ackah et al.
HUMAN MOLECULAR GENETICS (2017)
Microglial activation in Parkinson's disease using [18F]-FEPPA
Christine Ghadery et al.
JOURNAL OF NEUROINFLAMMATION (2017)
Human iPS cell-derived dopaminergic neurons function in a primate Parkinson's disease model
Tetsuhiro Kikuchi et al.
NATURE (2017)
T cells from patients with Parkinson's disease recognize α-synuclein peptides
David Sulzer et al.
NATURE (2017)
Cell diversity and network dynamics in photosensitive human brain organoids
Giorgia Quadrato et al.
NATURE (2017)
Neurotoxic reactive astrocytes are induced by activated microglia
Shane A. Liddelow et al.
NATURE (2017)
Microglia emerge as central players in brain disease
Michael W. Salter et al.
NATURE MEDICINE (2017)
Differentiation of human and murine induced pluripotent stem cells to microglia-like cells
Hetal Pandya et al.
NATURE NEUROSCIENCE (2017)
Generation of high-purity human ventral midbrain dopaminergic progenitors for in vitro maturation and intracerebral transplantation
Sara Nolbrant et al.
NATURE PROTOCOLS (2017)
iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases
Edsel M. Abud et al.
NEURON (2017)
Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells
Steven A. Sloan et al.
NEURON (2017)
Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain
Ira Espuny-Camacho et al.
NEURON (2017)
Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson's disease
Lena F. Burbulla et al.
SCIENCE (2017)
The Role of Astrocyte Dysfunction in Parkinson's Disease Pathogenesis
Heather D. E. Booth et al.
TRENDS IN NEUROSCIENCES (2017)
A Knockin Reporter Allows Purification and Characterization of mDA Neurons from Heterogeneous Populations
Ninuo Xia et al.
CELL REPORTS (2017)
Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells
Anna S. Monzel et al.
STEM CELL REPORTS (2017)
An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem Cells
T. C. W. Julia et al.
STEM CELL REPORTS (2017)
Directed Differentiation of Human Pluripotent Stem Cells to Microglia
Panagiotis Douvaras et al.
STEM CELL REPORTS (2017)
A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response
Walther Haenseler et al.
STEM CELL REPORTS (2017)
Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells
Antje Appelt-Menzel et al.
STEM CELL REPORTS (2017)
Mitochondrial impairment in microglia amplifies NLRP3 inflammasome proinflammatory signaling in cell culture and animal models of Parkinson's disease
Souvarish Sarkar et al.
NPJ PARKINSONS DISEASE (2017)
α-Synuclein in gut endocrine cells and its implications for Parkinson's disease
Rashmi Chandra et al.
JCI INSIGHT (2017)
Accelerated differentiation of human induced pluripotent stem cells to blood- brain barrier endothelial cells
Emma K. Hollmann et al.
FLUIDS AND BARRIERS OF THE CNS (2017)
LRRK2 levels in immune cells are increased in Parkinson'sdisease
D. A. Cook et al.
NPJ PARKINSONS DISEASE (2017)
A LUHMES 3D dopaminergic neuronal model for neurotoxicity testing allowing long-term exposure and cellular resilience analysis
L. Smirnova et al.
ARCHIVES OF TOXICOLOGY (2016)
Midbrain-like Organoids from Human Pluripotent Stem Cells Contain Functional Dopaminergic and Neuromelanin-Producing Neurons
Junghyun Jo et al.
CELL STEM CELL (2016)
Functional Impairment in Miro Degradation and Mitophagy Is a Shared Feature in Familial and Sporadic Parkinson's Disease
Chung-Han Hsieh et al.
CELL STEM CELL (2016)
LRRK2 modulates microglial activity through regulation of chemokine (C-X3-C) receptor 1-mediated signalling pathways
Bo Ma et al.
HUMAN MOLECULAR GENETICS (2016)
IL-6 serum levels are elevated in Parkinson's disease patients with fatigue compared to patients without fatigue
Jessica Ramos Pereira et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2016)
Astrocyte scar formation aids central nervous system axon regeneration
Mark A. Anderson et al.
NATURE (2016)
Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression
Frank Soldner et al.
NATURE (2016)
Efficient derivation of microglia-like cells from human pluripotent stem cells
Julien Muffat et al.
NATURE MEDICINE (2016)
Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse
Ye Zhang et al.
NEURON (2016)
Impairment of proteasome and anti-oxidative pathways in the induced pluripotent stem cell model for sporadic Parkinson's disease
Kuo-Hsuan Chang et al.
PARKINSONISM & RELATED DISORDERS (2016)
Leucine-Rich Repeat Kinase 2 Influences Fate Decision of Human Monocytes Differentiated from Induced Pluripotent Stem Cells
Anna Speidel et al.
PLOS ONE (2016)
How neuroinflammation contributes to neurodegeneration
Richard M. Ransohoff
SCIENCE (2016)
Quantification of dopaminergic neuron differentiation and neurotoxicity via a genetic reporter
Jun Cui et al.
SCIENTIFIC REPORTS (2016)
Molecular Features Underlying Neurodegeneration Identified through In Vitro Modeling of Genetically Diverse Parkinson's Disease Patients
Lin Lin et al.
CELL REPORTS (2016)
Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation
Sun Young Chung et al.
STEM CELL REPORTS (2016)
Genomics implicates adaptive and innate immunity in Alzheimer's and Parkinson's diseases
Sarah A. Gagliano et al.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2016)
Alterations of Myelin Content in Parkinson's Disease: A Cross-Sectional Neuroimaging Study
Douglas C. Dean et al.
PLOS ONE (2016)
Human Embryonic Stem Cell-Derived Oligodendrocyte Progenitors Remyelinate the Brain and Rescue Behavioral Deficits following Radiation
Jinghua Piao et al.
CELL STEM CELL (2015)
Striatal blood-brain barrier permeability in Parkinson's disease
Madison T. Gray et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2015)
Leucine-rich repeat kinase 2 positively regulates inflammation and down-regulates NF-κB p50 signaling in cultured microglia cells
Isabella Russo et al.
JOURNAL OF NEUROINFLAMMATION (2015)
Leucine-Rich Repeat Kinase 2 Modulates Neuroinflammation and Neurotoxicity in Models of Human Immunodeficiency Virus 1-Associated Neurocognitive Disorders
Jenna M. Puccini et al.
JOURNAL OF NEUROSCIENCE (2015)
LRRK2 G2019S mutation attenuates microglial motility by inhibiting focal adhesion kinase
Insup Choi et al.
NATURE COMMUNICATIONS (2015)
String Vessel Formation is Increased in the Brain of Parkinson Disease
Panzao Yang et al.
JOURNAL OF PARKINSONS DISEASE (2015)
Human Pluripotent Stem Cell-Derived Radial Glia Recapitulate Developmental Events and Provide Real-Time Access to Cortical Neurons and Astrocytes
Lishu Duan et al.
STEM CELLS TRANSLATIONAL MEDICINE (2015)
Alpha-Synuclein Expression in the Oligodendrocyte Lineage: an In Vitro and In Vivo Study Using Rodent and Human Models
Mehdi Djelloul et al.
STEM CELL REPORTS (2015)
Complex Deregulation and Expression of Cytokines and Mediators of the Immune Response in Parkinson's Disease Brain is Region Dependent
Paula Garcia-Esparcia et al.
BRAIN PATHOLOGY (2014)
Pharmacological Treatment of Parkinson Disease A Review
Barbara S. Connolly et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2014)
DJ-1 deficiency triggers microglia sensitivity dopamine toward a pro-inflammatory phenotype that is attenuated by rasagiline
Dorit Trudler et al.
JOURNAL OF NEUROCHEMISTRY (2014)
Identification of a unique TGF-β dependent molecular and functional signature in microglia
Oleg Butovsky et al.
NATURE NEUROSCIENCE (2014)
iPSC-derived neurons from GBA1-associated Parkinson's disease patients show autophagic defects and impaired calcium homeostasis
David C. Schoendorf et al.
NATURE COMMUNICATIONS (2014)
Parkinson's disease: animal models and dopaminergic cell vulnerability
Javier Blesa et al.
FRONTIERS IN NEUROANATOMY (2014)
Efficient Generation of Myelinating Oligodendrocytes from Primary Progressive Multiple Sclerosis Patients by Induced Pluripotent Stem Cells
Panagiotis Douvaras et al.
STEM CELL REPORTS (2014)
Human iPSC-Derived Oligodendrocyte Progenitor Cells Can Myelinate and Rescue a Mouse Model of Congenital Hypomyelination
Su Wang et al.
CELL STEM CELL (2013)
Genetic Correction of a LRRK2 Mutation in Human iPSCs Links Parkinsonian Neurodegeneration to ERK-Dependent Changes in Gene Expression
Peter Reinhardt et al.
CELL STEM CELL (2013)
Functional Maturation of hPSC-Derived Forebrain Interneurons Requires an Extended Timeline and Mimics Human Neural Development
Cory R. Nicholas et al.
CELL STEM CELL (2013)
Glial Influence on the Blood Brain Barrier
Jorge Ivan Alvarez et al.
GLIA (2013)
Neuronal Vulnerability, Pathogenesis, and Parkinson's Disease
David Sulzer et al.
MOVEMENT DISORDERS (2013)
Pathogenesis of Parkinson's Disease
Etienne C. Hirsch et al.
MOVEMENT DISORDERS (2013)
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice
Michael T. Heneka et al.
NATURE (2013)
Cerebral organoids model human brain development and microcephaly
Madeline A. Lancaster et al.
NATURE (2013)
Interplay of LRRK2 with chaperone-mediated autophagy
Samantha J. Orenstein et al.
NATURE NEUROSCIENCE (2013)
Triggering of Inflammasome by Aggregated α-Synuclein, an Inflammatory Response in Synucleinopathies
Gaia Codolo et al.
PLOS ONE (2013)
Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy
Andrea Serio et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
hESC-derived Olig2+ progenitors generate a subtype of astroglia with protective effects against ischaemic brain injury
Peng Jiang et al.
NATURE COMMUNICATIONS (2013)
Reprogramming aging and progeria
Jose M. P. Freije et al.
CURRENT OPINION IN CELL BIOLOGY (2012)
Aging and reprogramming: a two-way street
Salah Mahmoudi et al.
CURRENT OPINION IN CELL BIOLOGY (2012)
Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease
Adriana Sanchez-Danes et al.
EMBO MOLECULAR MEDICINE (2012)
Reduced T helper and B lymphocytes in Parkinson's disease
Claire H. Stevens et al.
JOURNAL OF NEUROIMMUNOLOGY (2012)
LRRK2 Inhibition Attenuates Microglial Inflammatory Responses
Mark S. Moehle et al.
JOURNAL OF NEUROSCIENCE (2012)
Genomic Analysis of Reactive Astrogliosis
Jennifer L. Zamanian et al.
JOURNAL OF NEUROSCIENCE (2012)
Progressive degeneration of human neural stem cells caused by pathogenic LRRK2
Guang-Hui Liu et al.
NATURE (2012)
Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson's Disease
Oliver Cooper et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Efficient Differentiation of Human Embryonic and Induced Pluripotent Stem Cells into Functional Astrocytes
Luni Emdad et al.
STEM CELLS AND DEVELOPMENT (2012)
Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations
Frank Soldner et al.
CELL (2011)
LRRK2 Mutant iPSC-Derived DA Neurons Demonstrate Increased Susceptibility to Oxidative Stress
Ha Nam Nguyen et al.
CELL STEM CELL (2011)
Mitochondrial Parkin Recruitment Is Impaired in Neurons Derived from Mutant PINK1 Induced Pluripotent Stem Cells
Philip Seibler et al.
JOURNAL OF NEUROSCIENCE (2011)
Directed differentiation of functional astroglial subtypes from human pluripotent stem cells
Robert Krencik et al.
NATURE PROTOCOLS (2011)
Neuroinflammation in Parkinson's disease
Etienne C. Hirsch et al.
PARKINSONISM & RELATED DISORDERS (2011)
Oligodendrocytes: biology and pathology
Monika Bradl et al.
ACTA NEUROPATHOLOGICA (2010)
Effect of endogenous mutant and wild-type PINK1 on Parkin in fibroblasts from Parkinson disease patients
Aleksandar Rakovic et al.
HUMAN MOLECULAR GENETICS (2010)
Genetic Animal Models of Parkinson's Disease
Ted M. Dawson et al.
NEURON (2010)
Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors
Frank Soldner et al.
CELL (2009)
Species Differences in Blood-Brain Barrier Transport of Three Positron Emission Tomography Radioligands with Emphasis on P-Glycoprotein Transport
Stina Syvanen et al.
DRUG METABOLISM AND DISPOSITION (2009)
Uniquely Hominid Features of Adult Human Astrocytes
Nancy Ann Oberheim et al.
JOURNAL OF NEUROSCIENCE (2009)
Neuroinflammation in Parkinson's disease: a target for neuroprotection?
Etienne C. Hirsch et al.
LANCET NEUROLOGY (2009)
Genomewide Association Study of Leprosy
Fu-Ren Zhang et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Disease-specific induced pluripotent stem cells
In-Hyun Park et al.
CELL (2008)
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
Jeffrey C. Barrett et al.
NATURE GENETICS (2008)
Peripheral inflammatory biomarkers and risk of Parkinson's disease
Honglei Chen et al.
AMERICAN JOURNAL OF EPIDEMIOLOGY (2008)
Induced pluripotent stem cell lines derived from human somatic cells
Junying Yu et al.
SCIENCE (2007)
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
Kazutoshi Takahashi et al.
CELL (2007)
Establishment of human tumor xenografts in immunodeficient mice
Christopher L. Morton et al.
NATURE PROTOCOLS (2007)
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
Kazutoshi Takahashi et al.
CELL (2006)
In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease
A Gerhard et al.
NEUROBIOLOGY OF DISEASE (2006)
Neurological and neurodegenerative alterations in a transgenic mouse model expressing human α-synuclein under oligodendrocyte promoter:: Implications for multiple system atrophy
CW Shults et al.
JOURNAL OF NEUROSCIENCE (2005)
6-Hydroxydopamine-induced alterations in blood-brain barrier permeability
PM Carvey et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2005)
Mouse model of multiple system atrophy α-synuclein expression in oligodendrocytes causes glial and neuronal degeneration
I Yazawa et al.
NEURON (2005)
Microglial activation and dopamine terminal loss in early Parkinson's disease
Y Ouchi et al.
ANNALS OF NEUROLOGY (2005)
Blood-brain barrier dysfunction in Parkinsonian midbrain in vivo
R Kortekaas et al.
ANNALS OF NEUROLOGY (2005)
Alterations of T-lymphocyte populations in Parkinson disease
Y Baba et al.
PARKINSONISM & RELATED DISORDERS (2005)
Molecular mechanisms controlling cortical gliogenesis
CM Sauvageot et al.
CURRENT OPINION IN NEUROBIOLOGY (2002)
NACP/alpha-synuclein-positive filamentous inclusions in astrocytes and oligodendrocytes of Parkinson's disease brains
K Wakabayashi et al.
ACTA NEUROPATHOLOGICA (2000)
Share Paper
