Journal
CELL STEM CELL
Volume 27, Issue 6, Pages 859-868Publisher
CELL PRESS
DOI: 10.1016/j.stem.2020.11.012
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Funding
- NIH [5DP1DA038043]
- NIDDK [1R01DK123746-01]
- NIAID [R01AI097552-01A1]
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SARS-CoV-2, the virus causing the current COVID-19 pandemic, primarily targets the airway epithelium and in lungs can lead to acute respiratory distress syndrome. Clinical studies in recent months have revealed that COVID-19 is a multi-organ disease causing characteristic complications. Stem cell models of various organ systems-most prominently, lung, gut, heart, and brain-are at the forefront of studies aimed at understanding the role of direct infection in COVID-19 multi-organ dysfunction.
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