4.0 Article

Fetal valproate syndrome with coronary arteriovenous fistula: a case report

Journal

CARDIOLOGY IN THE YOUNG
Volume 31, Issue 5, Pages 853-855

Publisher

CAMBRIDGE UNIV PRESS
DOI: 10.1017/S1047951120004904

Keywords

fetal valproate syndrome; coronary AV fistula; teratogenes

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Our case of coronary AV fistula in association with fetal valproate syndrome is the first reported in the literature. Despite challenges in differential diagnosis, a detailed history, physical examination, and appropriate laboratory tests are key in diagnosing the condition. Preventing fetal valproate syndrome can be achieved by discontinuing the use of valproic acid, especially during the first trimester of pregnancy.
Interestingly, our case presenting with coronary AV fistula firstly reported in the literature with fetal valproate syndrome. Although differential diagnosis is sometimes difficult, it can be diagnosed with detailed history, physical examination and appropriate laboratory tests. Fetal valproate syndrome can be prevented by discontinue of the valproic acid especially during first trimester of pregnancy.

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