Related references
Note: Only part of the references are listed.A hydrogen sulfide-releasing alginate dressing for effective wound healing
Xia Zhao et al.
ACTA BIOMATERIALIA (2020)
Biological Effects of Morpholin-4-Ium 4 Methoxyphenyl (Morpholino) Phosphinodithioate and Other Phosphorothioate-Based Hydrogen Sulfide Donors
Dawn Sijin Nin et al.
ANTIOXIDANTS & REDOX SIGNALING (2020)
The Benefits of Macromolecular/Supramolecular Approaches in Hydrogen Sulfide Delivery: A Review of Polymeric and Self-Assembled Hydrogen Sulfide Donors
Kuljeet Kaur et al.
ANTIOXIDANTS & REDOX SIGNALING (2020)
Hydrogen sulfide modulates epithelial-mesenchymal transition and angiogenesis in non-small cell lung cancer via HIF-1 alpha activation
Mingqi Wang et al.
BIOCHEMICAL PHARMACOLOGY (2020)
Activation of the reverse transsulfuration pathway through NRF2/CBS confers erastin-induced ferroptosis resistance
Nan Liu et al.
BRITISH JOURNAL OF CANCER (2020)
Ferroptosis, a novel pharmacological mechanism of anti-cancer drugs
Yanwei Su et al.
CANCER LETTERS (2020)
Potential role of the 3-mercaptopyruvate sulfurtransferase (3-MST)-hydrogen sulfide (H2S) pathway in cancer cells
Fiona Augsburger et al.
PHARMACOLOGICAL RESEARCH (2020)
Diallyl trisulfide, a H2S donor, inhibits cell growth of human papillary thyroid carcinoma KTC-1 cells through a positive feedback loop between H2S and cystathionine-gamma-lyase
Shichen Xu et al.
PHYTOTHERAPY RESEARCH (2020)
Structural and Functional Analyses of Human ChaC2 in Glutathione Metabolism
Yen T. K. Nguyen et al.
BIOMOLECULES (2020)
Uptake of collagen type I via macropinocytosis cause mTOR activation and anti-cancer drug resistance
Shota Yamazaki et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)
Thioredoxin regulates human mercaptopyruvate sulfurtransferase at physiologically-relevant concentrations
Pramod Kumar Yadav et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
Role of 3-Mercaptopyruvate Sulfurtransferase in the Regulation of Proliferation, Migration, and Bioenergetics in Murine Colon Cancer Cells
Fiona Augsburger et al.
BIOMOLECULES (2020)
Combination of host immune metabolic is biomarkers for the PD-1 blockade cancer immunotherapy
Ryusuke Hatae et al.
JCI INSIGHT (2020)
A Review of Hydrogen Sulfide Synthesis, Metabolism, and Measurement: Is Modulation of Hydrogen Sulfide a Novel Therapeutic for Cancer?
Xu Cao et al.
ANTIOXIDANTS & REDOX SIGNALING (2019)
Sulfasalazine could modulate the CD44v9-xCT system and enhance cisplatin-induced cytotoxic effects in metastatic bladder cancer
Koichiro Ogihara et al.
CANCER SCIENCE (2019)
Hydrogen Sulfide Oxidation: Adaptive Changes in Mitochondria of SW480 Colorectal Cancer Cells upon Exposure to Hypoxia
Francesca Malagrino et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)
Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance
Jonathan K. M. Lim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability
Mark R. Sullivan et al.
ELIFE (2019)
Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer
Yun Pyo Kang et al.
ELIFE (2019)
The Non-Essential Amino Acid Cysteine Becomes Essential for Tumor Proliferation and Survival
Joseph A. Combs et al.
CANCERS (2019)
A novel hydrogen sulfide-releasing donor, HA-ADT, suppresses the growth of human breast cancer cells through inhibiting the PI3K/AKT/mTOR and Ras/Raf/MEK/ERK signaling pathways
Qian Dong et al.
CANCER LETTERS (2019)
ASCT2: a potential cancer drug target
Kanu Wahi et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2019)
Hydrogen sulfide perturbs mitochondrial bioenergetics and triggers metabolic reprogramming in colon cells
Marouane Libiad et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Alterations of Methionine Metabolism as Potential Targets for the Prevention and Therapy of Hepatocellular Carcinoma
Rosa M. Pascale et al.
MEDICINA-LITHUANIA (2019)
Identification of differentially expressed genes regulated by methylation in colon cancer based on bioinformatics analysis
Yu Liang et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2019)
Glutaminolysis-related genes determine sensitivity to xCT-targeted therapy in head and neck squamous cell carcinoma
Shogo Okazaki et al.
CANCER SCIENCE (2019)
L-Buthionine Sulfoximine Detection and Quantification in Polyurea Dendrimer Nanoformulations
Pedro Mota et al.
MOLECULES (2019)
N-Acetylcysteine Serves as Substrate of 3-Mercaptopyruvate Sulfurtransferase and Stimulates Sulfide Metabolism in Colon Cancer Cells
Karim Zuhra et al.
CELLS (2019)
Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation
Jiajun Zhu et al.
CELL METABOLISM (2019)
Mitochondrial MTHFD isozymes display distinct expression, regulation, and association with cancer
R. Nilsson et al.
GENE (2019)
The chemical basis of ferroptosis
Marcus Conrad et al.
NATURE CHEMICAL BIOLOGY (2019)
Hydrogen Sulfide: Emerging Role in Bladder, Kidney, and Prostate Malignancies
Masoud Akbari et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)
Targeting Glutathione and Cystathionine β-Synthase in Ovarian Cancer Treatment by Selenium-Chrysin Polyurea Dendrimer Nanoformulation
Ines Santos et al.
NUTRIENTS (2019)
Low-Concentration PTX And RSL3 Inhibits Tumor Cell Growth Synergistically By Inducing Ferroptosis In Mutant p53 Hypopharyngeal Squamous Carcinoma
Jing Ye et al.
CANCER MANAGEMENT AND RESEARCH (2019)
Cysteine-derived hydrogen sulfide and gut health: a matter of endogenous or bacterial origin
Francois Blachier et al.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2019)
Inhibition of hydrogen sulfide synthesis reverses acquired resistance to 5-FU through miR-215-5p-EREG/TYMS axis in colon cancer cells
Shanwen Chen et al.
CANCER LETTERS (2019)
Glutamine Addiction and Therapeutic Strategies in Lung Cancer
Karolien Vanhove et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Hydrogen sulphide-releasing aspirin enhances cell capabilities of anti-oxidative lesions and anti-inflammation
An-Sha Zhao et al.
MEDICAL GAS RESEARCH (2019)
Cysteine catabolism and the serine biosynthesis pathway support pyruvate production during pyruvate kinase knockdown in pancreatic cancer cells
Lei Yu et al.
CANCER & METABOLISM (2019)
A Catalytic Trisulfide in Human Sulfide Quinone Oxidoreductase Catalyzes Coenzyme A Persulfide Synthesis and Inhibits Butyrate Oxidation
Aaron P. Landry et al.
CELL CHEMICAL BIOLOGY (2019)
Drug resistance induces the upregulation of H2S-producing enzymes in HCT116 colon cancer cells
Ashley A. Untereiner et al.
BIOCHEMICAL PHARMACOLOGY (2018)
CISD2 inhibition overcomes resistance to sulfasalazine-induced ferroptotic cell death in head and neck cancer
Eun Hye Kim et al.
CANCER LETTERS (2018)
Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis
Irina Ingold et al.
CELL (2018)
Implications of plasma thiol redox in disease
Percillia V. S. Oliveira et al.
CLINICAL SCIENCE (2018)
Functional characterisation of glutathione export from the rat lens
Ankita Umapathy et al.
EXPERIMENTAL EYE RESEARCH (2018)
Glutathione in Ovarian Cancer: A Double-Edged Sword
Sofia C. Nunes et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Synthesis of multi-omit data and community metabolic models reveals insights into the role of hydrogen sulfide in colon cancer
Vanessa L. Hale et al.
METHODS (2018)
Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models
Michael L. Schulte et al.
NATURE MEDICINE (2018)
xCT (SLC7A11)-mediated metabolic reprogramming promotes non-small cell lung cancer progression
Xiangming Ji et al.
ONCOGENE (2018)
Hydrogen Sulfide Biochemistry and Interplay with Other Gaseous Mediators in Mammalian Physiology
Alessandro Giuffre et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)
One-carbon metabolism biomarkers and genetic variants in relation to colorectal cancer risk by KRAS and BRAF mutation status
Robin Myte et al.
PLOS ONE (2018)
Dysfunction in the mitochondrial Fe-S assembly machinery leads to formation of the chemoresistant truncated VDAC1 isoform without HIF-1α activation
Ioana Ferecatu et al.
PLOS ONE (2018)
Possible role of hydrogen sulfide as an endogenous relaxation factor in the rat bladder and prostate
Suo Zou et al.
NEUROUROLOGY AND URODYNAMICS (2018)
Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation
Gaojian Lian et al.
ELIFE (2018)
Cystathione beta-Synthase Is Increased in Thyroid Malignancies
Elba A. Turbat-Herrera et al.
ANTICANCER RESEARCH (2018)
Efflux inhibition by H2S confers sensitivity to doxorubicin-induced cell death in liver cancer cells
Eric Stokes et al.
LIFE SCIENCES (2018)
mTOR signalling and cellular metabolism are mutual determinants in cancer
Dirk Mossmann et al.
NATURE REVIEWS CANCER (2018)
Chemical Biology of H2S Signaling through Persulfidation
Milos R. Filipovic et al.
CHEMICAL REVIEWS (2018)
The Role of Cystinosin in the Intermediary Thiol Metabolism and Redox Homeostasis in Kidney Proximal Tubular Cells
Rodolfo Sumayao et al.
ANTIOXIDANTS (2018)
H2S biosynthesis and catabolism: new insights from molecular studies
Peter Rose et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2017)
Molecular Portrait of Metastasis-Competent Circulating Tumor Cells in Colon Cancer Reveals the Crucial Role of Genes Regulating Energy Metabolism and DNA Repair
Catherine Alix-Panabieres et al.
CLINICAL CHEMISTRY (2017)
ChaC2, an Enzyme for Slow Turnover of Cytosolic Glutathione
Amandeep Kaur et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth
Shiro L. Cramer et al.
NATURE MEDICINE (2017)
Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors
Shawn M. Davidson et al.
NATURE MEDICINE (2017)
xCT deficiency aggravates acetaminophen-induced hepatotoxicity under inhibition of the transsulfuration pathway
Eun Sil Kang et al.
FREE RADICAL RESEARCH (2017)
The one-carbon metabolism pathway highlights therapeutic targets for gastrointestinal cancer (Review)
Masamitsu Konn et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2017)
H2S oxidation by nanodisc-embedded human sulfide quinone oxidoreductase
Aaron P. Landry et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
The glutamate/cystine antiporter SLC7A11/xCT enhances cancer cell dependency on glucose by exporting glutamate
Pranavi Koppula et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Glutamine Transporters Are Targets of Multiple Oncogenic Signaling Pathways in Prostate Cancer
Mark A. White et al.
MOLECULAR CANCER RESEARCH (2017)
mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT
Yuchao Gu et al.
MOLECULAR CELL (2017)
NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis
Samantha W. Alvarez et al.
NATURE (2017)
Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
Vasanthi S. Viswanathan et al.
NATURE (2017)
Oncogenic PI3K promotes methionine dependency in breast cancer cells through the cystine-glutamate antiporter xCT
Evan C. Lien et al.
SCIENCE SIGNALING (2017)
Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics
Takaaki Akaike et al.
NATURE COMMUNICATIONS (2017)
Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism
Douglas E. Biancur et al.
NATURE COMMUNICATIONS (2017)
Glutaminolysis drives membrane trafficking to promote invasiveness of breast cancer cells
Emmanuel Dornier et al.
NATURE COMMUNICATIONS (2017)
Cystathionine- γ-lyase promotes process of breast cancer in association with STAT3 signaling pathway
Jing You et al.
ONCOTARGET (2017)
A prospective study of serum metabolites and glioma risk
Jiaqi Huang et al.
ONCOTARGET (2017)
Exploiting ROS and metabolic differences to kill cisplatin resistant lung cancer
Medhi Wangpaichitr et al.
ONCOTARGET (2017)
Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST)Targeting Active-site Cysteine Persulfide
Kenjiro Hanaoka et al.
SCIENTIFIC REPORTS (2017)
Cysteine transporter SLC3A1 promotes breast cancer tumorigenesis
Yang Jiang et al.
THERANOSTICS (2017)
Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition
Alexander Muir et al.
ELIFE (2017)
Oncogenic PI3K promotes methionine dependency in breast cancer cells through the cystine-glutamate antiporter xCT
Evan C. Lien et al.
SCIENCE SIGNALING (2017)
Cysteine Dioxygenase 1 Mediates Erastin-Induced Ferroptosis in Human Gastric Cancer Cells
Shihui Hao et al.
NEOPLASIA (2017)
Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis
Ches'Nique M. Phillips et al.
CANCER RESEARCH (2017)
mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient
Gregory A. Wyant et al.
CELL (2017)
The Reactive Species Interactome: Evolutionary Emergence, Biological Significance, and Opportunities for Redox Metabolomics and Personalized Medicine
Miriam M. Cortese-Krott et al.
ANTIOXIDANTS & REDOX SIGNALING (2017)
Betaine homocysteine S-methyltransferase emerges as a new player of the nuclear methionine cycle
Juliana Perez-Miguelsanz et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2017)
Enzymes involved in branched-chain amino acid metabolism in humans
Maria M. Adeva-Andany et al.
AMINO ACIDS (2017)
Use of Tissue Metabolite Analysis and Enzyme Kinetics To Discriminate between Alternate Pathways for Hydrogen Sulfide Metabolism
Kristie D. Cox Augustyn et al.
BIOCHEMISTRY (2017)
Catalytic promiscuity and heme-dependent redox regulation of H2S synthesis
Ruma Banerjee
CURRENT OPINION IN CHEMICAL BIOLOGY (2017)
Biological chemistry of hydrogen sulfide and persulfides
Ernesto Cuevasanta et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2017)
The Regulation and Function of Lactate Dehydrogenase A: Therapeutic Potential in Brain Tumor
Cara J. Valvona et al.
BRAIN PATHOLOGY (2016)
S-Adenosyl-L-methionine Modulates CO and NO• Binding to the Human H2S-generating Enzyme Cystathionine β-Synthase
Joao B. Vicente et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Biosynthesis and Reactivity of Cysteine Persulfides in Signaling
Pramod K. Yadav et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)
Gasotransmitters in cancer: from pathophysiology to experimental therapy
Csaba Szabo
NATURE REVIEWS DRUG DISCOVERY (2016)
HNF1β drives glutathione (GSH) synthesis underlying intrinsic carboplatin resistance of ovarian clear cell carcinoma (OCCC)
Filipa Lopes-Coelho et al.
TUMOR BIOLOGY (2016)
Prospective study of serum cysteine and cysteinylglycine and cancer of the head and neck, esophagus, and stomach in a cohort of male smokers
Eugenia H. Miranti et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2016)
Endogenous Hydrogen Sulfide Enhances Cell Proliferation of Human Gastric Cancer AGS Cells
Fumiko Sekiguchi et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2016)
Promoter methylation status of tumor suppressor genes and inhibition of expression of DNA methyltransferase 1 in non-small cell lung cancer
Bangqing Liu et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2016)
Glutamate Oxidation in Astrocytes: Roles of Glutamate Dehydrogenase and Aminotransferases
Mary C. McKenna et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2016)
Increased Expression of System xc- in Glioblastoma Confers an Altered Metabolic State and Temozolomide Resistance
Monika D. Polewski et al.
MOLECULAR CANCER RESEARCH (2016)
Alkylating Agent-Induced NRF2 Blocks Endoplasmic Reticulum Stress-Mediated Apoptosis via Control of Glutathione Pools and Protein Thiol Homeostasis
Alfeu Zanotto-Filho et al.
MOLECULAR CANCER THERAPEUTICS (2016)
Cystathionine-β-Synthase Inhibition for Colon Cancer: Enhancement of the Efficacy of Aminooxyacetic Acid via the Prodrug Approach
Celia Chao et al.
MOLECULAR MEDICINE (2016)
Glutathione biosynthesis is a metabolic vulnerability in PI(3)K/Akt-driven breast cancer
Evan C. Lien et al.
NATURE CELL BIOLOGY (2016)
Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine β-synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of colon cancer
Nadiya Druzhyna et al.
PHARMACOLOGICAL RESEARCH (2016)
S-Sulfhydration of ATP synthase by hydrogen sulfide stimulates mitochondrial bioenergetics
Katalin Modis et al.
PHARMACOLOGICAL RESEARCH (2016)
Glutathione-mediated antioxidant response and aerobic metabolism: two crucial factors involved in determining the multi-drug resistance of high-risk neuroblastoma
Renata Colla et al.
ONCOTARGET (2016)
Inhibition of hydrogen sulfide biosynthesis sensitizes lung adenocarcinoma to chemotherapeutic drugs by inhibiting mitochondrial DNA repair and suppressing cellular bioenergetics
Bartosz Szczesny et al.
SCIENTIFIC REPORTS (2016)
S-Glutathionylation Enhances Human Cystathionine β-Synthase Activity Under Oxidative Stress Conditions
Wei-Ning Niu et al.
ANTIOXIDANTS & REDOX SIGNALING (2015)
The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38-and oxaliplatin-induced death of drug-resistant colorectal cancer cells
Elena Pedraz-Cuesta et al.
BMC CANCER (2015)
Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression
Isaac S. Harris et al.
CANCER CELL (2015)
Human Pancreatic Cancer Tumors Are Nutrient Poor and Tumor Cells Actively Scavenge Extracellular Protein
Jurre J. Kamphorst et al.
CANCER RESEARCH (2015)
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions
Linchong Sun et al.
CELL RESEARCH (2015)
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is inactivated by S-sulfuration in vitro
Artur P. Jarosz et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
Role of cystathionine β-synthase in human breast Cancer
Suvajit Sen et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
Exogenous hydrogen sulfide exerts proliferation/anti-apoptosis/angiogenesis/migration effects via amplifying the activation of NF-κB pathway in PLC/PRF/5 hepatoma cells
Yulan Zhen et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2015)
Transient Kinetic Analysis of Hydrogen Sulfide Oxidation Catalyzed by Human Sulfide Quinone Oxidoreductase
Tatiana V. Mishanina et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Targeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour development
Qian Wang et al.
JOURNAL OF PATHOLOGY (2015)
A metabolomic approach to identifying platinum resistance in ovarian cancer
Laila M. Poisson et al.
JOURNAL OF OVARIAN RESEARCH (2015)
Inhibitors of glutamate release from breast cancer cells; new targets for cancer-induced bone-pain
Jennifer Fazzari et al.
SCIENTIFIC REPORTS (2015)
Expression of xCT and activity of system X-c(-) are regulated by NRF2 in human breast cancer cells in response to oxidative stress
Eric Habib et al.
REDOX BIOLOGY (2015)
Primary hepatocytes from mice lacking cysteine dioxygenase show increased cysteine concentrations and higher rates of metabolism of cysteine to hydrogen sulfide and thiosulfate
Halina Jurkowska et al.
AMINO ACIDS (2014)
Enzymology of H2S Biogenesis, Decay and Signaling
Omer Kabil et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Regulation of Cystathionine γ-Lyase in Mammalian Cells by Hypoxia
Maoxian Wang et al.
BIOCHEMICAL GENETICS (2014)
Role of Glutathione, Glutathione Transferase, and Glutaredoxin in Regulation of Redox-Dependent Processes
E. V. Kalinina et al.
BIOCHEMISTRY-MOSCOW (2014)
Cysteine Catabolism: A Novel Metabolic Pathway Contributing to Glioblastoma Growth
Antony Prabhu et al.
CANCER RESEARCH (2014)
Regulation of Ferroptotic Cancer Cell Death by GPX4
Wan Seok Yang et al.
CELL (2014)
Changes in the expression of the glutamate transporter EAAT3/EAAC1 in health and disease
Massimiliano G. Bianchi et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2014)
Reduced Expression of miRNA-27a Modulates Cisplatin Resistance in Bladder Cancer by Targeting the Cystine/Glutamate Exchanger SLC7A11
Ross M. Drayton et al.
CLINICAL CANCER RESEARCH (2014)
High homocysteine is associated with increased risk of colorectal cancer independently of oxidative stress and antioxidant capacities
Feng-Fan Chiang et al.
CLINICAL NUTRITION (2014)
S-sulfhydration of MEK1 leads to PARP-1 activation and DNA damage repair
Kexin Zhao et al.
EMBO REPORTS (2014)
Folate: Metabolism, genes, polymorphisms and the associated diseases
Fakhira Hassan Nazki et al.
GENE (2014)
Characterization and Interaction Studies of Two Isoforms of the Dual Localized 3-Mercaptopyruvate Sulfurtransferase TUM1 from Humans
Benjamin Fraesdorf et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Inter-domain Communication of Human Cystathionine β-Synthase STRUCTURAL BASIS OF S-ADENOSYL-L-METHIONINE ACTIVATION
Thomas J. McCorvie et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Organization of the Human Mitochondrial Hydrogen Sulfide Oxidation Pathway
Marouane Libiad et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
NO•Binds Human Cystathionine β- Synthase Quickly and Tightly
Joao B. Vicente et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
xCT, component of cysteine/glutamate transporter, as an independent prognostic factor in human esophageal squamous cell carcinoma
Atsushi Shiozaki et al.
JOURNAL OF GASTROENTEROLOGY (2014)
Glutamate and its receptors in cancer
Andrzej Stepulak et al.
JOURNAL OF NEURAL TRANSMISSION (2014)
Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics
Linn Fagerberg et al.
MOLECULAR & CELLULAR PROTEOMICS (2014)
Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling
Tomoaki Ida et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Serine and glycine metabolism in cancer
Ivano Amelio et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
Serine, but Not Glycine, Supports One-Carbon Metabolism and Proliferation of Cancer Cells
Christiaan F. Labuschagne et al.
CELL REPORTS (2014)
Homocysteine, cysteine, and risk of incident colorectal cancer in the Women's Health Initiative observational cohort
Joshua W. Miller et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2013)
Identification of Cystathionine -Synthase Inhibitors Using a Hydrogen Sulfide Selective Probe
Megan K. Thorson et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)
Hydrogen Sulfide Protects Against Cellular Senescence via S-Sulfhydration of Keap1 and Activation of Nrf2
Guangdong Yang et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Structural Consequences of Cysteinylation of Cu/Zn-Superoxide Dismutase
Jared R. Auclair et al.
BIOCHEMISTRY (2013)
Post-Translational Modification by Cysteine Protects Cu/Zn-Superoxide Dismutase from Oxidative Damage
Jared R. Auclair et al.
BIOCHEMISTRY (2013)
Selectivity of commonly used pharmacological inhibitors for cystathionine synthase (CBS) and cystathionine lyase (CSE)
Antonia Asimakopoulou et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
Glutamine Sensitivity Analysis Identifies the xCT Antiporter as a Common Triple-Negative Breast Tumor Therapeutic Target
Luika A. Timmerman et al.
CANCER CELL (2013)
Frequent Inactivation of Cysteine Dioxygenase Type 1 Contributes to Survival of Breast Cancer Cells and Resistance to Anthracyclines
Jana Jeschke et al.
CLINICAL CANCER RESEARCH (2013)
Intramitochondrial hydrogen sulfide production by 3-mercaptopyruvate sulfurtransferase maintains mitochondrial electron flow and supports cellular bioenergetics
Katalin Modis et al.
FASEB JOURNAL (2013)
Structure and Kinetic Analysis of H2S Production by Human Mercaptopyruvate Sulfurtransferase
Pramod Kumar Yadav et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
Cosimo Commisso et al.
NATURE (2013)
Role of Glutathione in Cancer Progression and Chemoresistance
Nicola Traverso et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)
Testing the Ability of Non-Methylamine Osmolytes Present in Kidney Cells to Counteract the Deleterious Effects of Urea on Structure, Stability and Function of Proteins
Sheeza Khan et al.
PLOS ONE (2013)
Cystathionine Beta-Synthase (CBS) Contributes to Advanced Ovarian Cancer Progression and Drug Resistance
Sanjib Bhattacharyya et al.
PLOS ONE (2013)
Tumor-derived hydrogen sulfide, produced by cystathionine-β-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer
Csaba Szabo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Oxygen-sensitive mitochondrial accumulation of cystathionine β-synthase mediated by Lon protease
Huajian Teng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
High Turnover Rates for Hydrogen Sulfide Allow for Rapid Regulation of Its Tissue Concentrations
Victor Vitvitsky et al.
ANTIOXIDANTS & REDOX SIGNALING (2012)
Human Sulfide:Quinone Oxidoreductase Catalyzes the First Step in Hydrogen Sulfide Metabolism and Produces a Sulfane Sulfur Metabolite
Michael R. Jackson et al.
BIOCHEMISTRY (2012)
Sulphide quinone reductase contributes to hydrogen sulphide metabolism in murine peripheral tissues but not in the CNS
D. R. Linden et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Serum Glutamate Levels Correlate with Gleason Score and Glutamate Blockade Decreases Proliferation, Migration, and Invasion and Induces Apoptosis in Prostate Cancer Cells
Shahriar Koochekpour et al.
CLINICAL CANCER RESEARCH (2012)
Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia
Wan Zhang et al.
NATURE CELL BIOLOGY (2012)
VALPROIC ACID INDUCES THE GLUTAMATE TRANSPORTER EXCITATORY AMINO ACID TRANSPORTER-3 IN HUMAN OLIGODENDROGLIOMA CELLS
M. G. Bianchi et al.
NEUROSCIENCE (2012)
Cysteine Dioxygenase 1 Is a Tumor Suppressor Gene Silenced by Promoter Methylation in Multiple Human Cancers
Mariana Brait et al.
PLOS ONE (2012)
Hydrogen sulfide (H2S) metabolism in mitochondria and its regulatory role in energy production
Ming Fu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The Quantitative Significance of the Transsulfuration Enzymes for H2S Production in Murine Tissues
Omer Kabil et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
Hydrogen Sulfide and Hemeproteins: Knowledge and Mysteries
Ruth Pietri et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc- and Thereby Promotes Tumor Growth
Takatsugu Ishimoto et al.
CANCER CELL (2011)
Mechanistic study of BNP7787-mediated cisplatin nephroprotection: modulation of human aminopeptidase N
F. H. Hausheer et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2011)
Serine Metabolism: Some Tumors Take the Road Less Traveled
Ralph J. DeBerardinis
CELL METABOLISM (2011)
Hydrogen Sulfide as Endothelium-Derived Hyperpolarizing Factor Sulfhydrates Potassium Channels
Asif K. Mustafa et al.
CIRCULATION RESEARCH (2011)
Prospective study of serum cysteine levels and oesophageal and gastric cancers in China
Gwen Murphy et al.
GUT (2011)
Effects of Altered Maternal Folic Acid, Vitamin B12 and Docosahexaenoic Acid on Placental Global DNA Methylation Patterns in Wistar Rats
Asmita Kulkarni et al.
PLOS ONE (2011)
Extracellular transsulfuration generates hydrogen sulfide from homocysteine and protects endothelium from redox stress
Shawn E. Bearden et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2010)
Plasma Homocysteine and Cysteine and Risk of Breast Cancer in Women
Jennifer Lin et al.
CANCER RESEARCH (2010)
Glutathione dysregulation and the etiology and progression of human diseases
Nazzareno Ballatori et al.
BIOLOGICAL CHEMISTRY (2009)
Cysteinylation and homocysteinylation of plasma protein thiols during ageing of healthy human beings
R. Rossi et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2009)
Hydrogen sulfide is an endogenous stimulator of angiogenesis
Andreas Papapetropoulos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
The xc- cystine/glutamate antiporter:: A potential target for therapy of cancer and other diseases
Maisie Lo et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2008)
Diurnal variation in glutathione and cysteine redox states in human plasmas
Roberto A. Blanco et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2007)
The novel proangiogenic effect of hydrogen sulfide is dependent on Akt phosphorylation
Wen-Jie Cai et al.
CARDIOVASCULAR RESEARCH (2007)
Involvement of disulfide bond formation in the activation of heparanase
Siro Simizu et al.
CANCER RESEARCH (2007)
Overexpression of cysteine dioxygenase reduces intracellular cysteine and glutathione pools in HepG2/C3A cells
John E. Dominy et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)
Profiling at mRNA, protein, and metabolite levels reveals alterations in renal amino acid handling and glutathione metabolism in kidney tissue of Pept2-/- mice
Isabelle M. Frey et al.
PHYSIOLOGICAL GENOMICS (2007)
Sulfasalazine-induced cystine starvation: Potential use for prostate cancer therapy
Daniel W. Doxsee et al.
PROSTATE (2007)
Human cystathionine β-synthase is a target for sumoylation
Omer Kabil et al.
BIOCHEMISTRY (2006)
Direct stimulation of KATP channels by exogenous and endogenous hydrogen sulfide in vascular smooth muscle cells
GH Tang et al.
MOLECULAR PHARMACOLOGY (2005)
Redox imbalance in cystine/glutamate transporter-deficient mice
H Sato et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Redox regulation and reaction mechanism of human cystathionine-beta-synthase: a PLP-dependent hemesensor protein
R Banerjee et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2005)
Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid
JH Suh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Glutathione metabolism and its implications for health
GY Wu et al.
JOURNAL OF NUTRITION (2004)
Regulation of cysteine dioxygenase and γ-glutamylcysteine synthetase is associated with hepatic cysteine level
JI Lee et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2004)
Plasma albumin cysteinylation is regulated by cystathionine β-synthase
D Bar-Or et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Sulfur amino acid metabolism: Pathways for production and removal of homocysteine and cysteine
MH Stipanuk
ANNUAL REVIEW OF NUTRITION (2004)
Extracellular thiols and thiol/disulfide redox in metabolism
SE Moriarty-Craige et al.
ANNUAL REVIEW OF NUTRITION (2004)
Expression and functional role of mGluR3 and mGluR5 in human astrocytes and glioma cells: opposite regulation of glutamate transporter proteins
E Aronica et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2003)
Role of cystine transport in intracellular glutathione level and cisplatin resistance in human ovarian cancer cell lines
S Okuno et al.
BRITISH JOURNAL OF CANCER (2003)
A functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the one-carbon unit for cell metabolism
MA Nikiforov et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
COMT genotype, micronutrients in the folate metabolic pathway and breast cancer risk
JE Goodman et al.
CARCINOGENESIS (2001)
Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the xc- cystine transporter:: a new action for an old drug
PW Gout et al.
LEUKEMIA (2001)
Cysteine regulates expression of cysteine dioxygenase and γ-glutamylcysteine synthetase in cultured rat hepatocytes
YH Kwon et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2001)
Cysteinylation of MHC class II ligands: Peptide endocytosis and reduction within APC influences T cell recognition
MA Haque et al.
JOURNAL OF IMMUNOLOGY (2001)
The quantitatively important relationship between homocysteine metabolism and glutathione synthesis by the transsulfuration pathway and its regulation by redox changes
E Mosharov et al.
BIOCHEMISTRY (2000)
Pathways and regulation of homocysteine metabolism in mammals
JD Finkelstein
SEMINARS IN THROMBOSIS AND HEMOSTASIS (2000)
Share Paper
