Pathogenic gene prediction based on network embedding

In disease research, the study of gene-disease correlation has always been an important topic. With the emergence of large-scale connected data sets in biology, we use known correlations between the entities, which may be from different sets, to build a biological heterogeneous network and propose a new network embedded representation algorithm to calculate the correlation between disease and genes, using the correlation score to predict pathogenic genes. Then, we conduct several experiments to compare our method to other state-of-the-art methods. The results reveal that our method achieves better performance than the traditional methods.

Automated summary

The study focuses on gene-disease correlation in disease research. By using large-scale connected data sets in biology, a new network embedded representation algorithm is proposed to predict pathogenic genes effectively compared to traditional methods.