Related references
Note: Only part of the references are listed.A new class of diamide scaffold: Design, synthesis and biological evaluation as potent antimitotic agents, tubulin polymerization inhibition and apoptosis inducing activity studies
Khaled O. Mohamed et al.
BIOORGANIC CHEMISTRY (2019)
Novel β-keto-enol Pyrazolic Compounds as Potent Antifungal Agents. Design, Synthesis, Crystal Structure, DFT, Homology Modeling, and Docking Studies
Said Tighadouini et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2019)
Haptic-Assisted Interactive Molecular Docking Incorporating Receptor Flexibility
Nick Matthews et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2019)
Cryo-EM structure of human mTOR complex 2
Xizi Chen et al.
CELL RESEARCH (2018)
Discovery of Pyridopyrimidinones as Potent and Orally Active Dual Inhibitors of PI3K/mTOR
Tao Yu et al.
ACS MEDICINAL CHEMISTRY LETTERS (2018)
In Silico Discovery of a Small Molecule Suppressing Lung Carcinoma A549 Cells Proliferation and Inducing Autophagy via mTOR Pathway Inhibition
Jiyuan Liu et al.
MOLECULAR PHARMACEUTICS (2018)
Scutellarin derivatives as apoptosis inducers: Design, synthesis and biological evaluation
Tong Han et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
Design, Synthesis, and Biological Evaluation of Dimorpholine Substituted Thienopyrimidines as Potential Class I PI3K/mTOR Dual Inhibitors
Miao Zhan et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
3D-QSAR, molecular dynamics simulations, and molecular docking studies on pyridoaminotropanes and tetrahydroquinazoline as mTOR inhibitors
Udit Chaube et al.
MOLECULAR DIVERSITY (2017)
Design, Synthesis and Biological Evaluation of novel Hedgehog Inhibitors for treating Pancreatic Cancer
Vinod Kumar et al.
SCIENTIFIC REPORTS (2017)
Antioxidant and antitumor efficacy of Luteolin, a dietary flavone on benzo(a) pyrene-induced experimental lung carcinogenesis
Eshvendar Reddy Kasala et al.
BIOMEDICINE & PHARMACOTHERAPY (2016)
3D-QSAR, molecular dynamics simulations and molecular docking studies of benzoxazepine moiety as mTOR inhibitor for the treatment of lung cancer
Udit Chaube et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)
Design, synthesis and anti-HIV activity of novel quinoxaline derivatives
Saloni B. Patel et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
PI3K/Akt/mTOR and Ras/Raf/MEK/ERK signaling pathways inhibitors as anticancer agents: Structural and pharmacological perspectives
Vivek Asati et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
3D-QSAR studies on 5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxamide derivatives as HIV-1 integrase inhibitors
Saloni Patel et al.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS (2016)
Design, synthesis and anticancer activities of novel otobain derivatives
Zhongzhou Li et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2016)
Molecular histology of lung cancer: From targets to treatments
Steven L. Wood et al.
CANCER TREATMENT REVIEWS (2015)
Antiproliferative and antioxidant potential of hesperetin against benzo(a)pyrene-induced lung carcinogenesis in Swiss albino mice
Lakshmi Narendra Bodduluru et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2015)
PDK1 orchestrates early NK cell development through induction of E4BP4 expression and maintenance of IL-15 responsiveness
Meixiang Yang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2015)
Discovery of Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor CC-223
Deborah S. Mortensen et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Nicotine induces resistance to erlotinib via cross-talk between α 1 nAChR and EGFR in the non-small cell lung cancer xenograft model
Heyan Li et al.
LUNG CANCER (2015)
mTORC2 controls cancer cell survival by modulating gluconeogenesis
M. W. Khan et al.
CELL DEATH DISCOVERY (2015)
Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer
Claudia Fumarola et al.
BIOCHEMICAL PHARMACOLOGY (2014)
Synthesis of 5-substituted-1H-pyrazolo [4,3-d] pyrimidin-7(6H)-one analogs and their biological evaluation as anticancer agents: mTOR inhibitors
G. Lakshma Reddy et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)
Napyradiomycin Derivatives, Produced by a Marine-Derived Actinomycete, Illustrate Cytotoxicity by Induction of Apoptosis
Lauge Farnaes et al.
JOURNAL OF NATURAL PRODUCTS (2014)
Flavonoids, Flavonoid Metabolites, and Phenolic Acids Inhibit Oxidative Stress in the Neuronal Cell Line HT-22 Monitored by ECIS and MTT Assay: A Comparative Study
Beata Kling et al.
JOURNAL OF NATURAL PRODUCTS (2014)
Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway
Jiri Polivka et al.
PHARMACOLOGY & THERAPEUTICS (2014)
mTOR kinase structure, mechanism and regulation
Haijuan Yang et al.
NATURE (2013)
Pharmacophore modeling, virtual screening and 3D-QSAR studies of 5-tetrahydroquinolinylidine aminoguanidine derivatives as sodium hydrogen exchanger inhibitors
Hardik G. Bhatt et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers
Ramaswamy Govindan et al.
CELL (2012)
Non-small cell lung cancer in never smokers: a clinical entity to be identified
Ilka Lopes Santoro et al.
CLINICS (2011)
Targeting the mTOR kinase domain: the second generation of mTOR inhibitors
Yan-Jie Zhang et al.
DRUG DISCOVERY TODAY (2011)
Synthesis of 6-Nitro-1,2,3,4-tetrahydroquinoline: An Experimental and Theoretical Study of Regioselective Nitration
Alessandra Cordeiro et al.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2011)
Synthesis and Significant Cytostatic Activity of 7-Hetaryl-7-deazaadenosines
Aurelie Bourderioux et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Diverse somatic mutation patterns and pathway alterations in human cancers
Zhengyan Kan et al.
NATURE (2010)
mTOR Inhibitor RAD001 (Everolimus) Has Antiangiogenic/Vascular Properties Distinct from a VEGFR Tyrosine Kinase Inhibitor
Heidi A. Lane et al.
CLINICAL CANCER RESEARCH (2009)
Protective effect of piperine on benzo(a)pyrene-induced lung carcinogenesis in Swiss albino mice
K Selvendiran et al.
CLINICA CHIMICA ACTA (2004)
Share Paper
