Recent advances in antibacterial agents

Antimicrobial resistance is a global challenge and the effectiveness of old antibiotics is decreasing. Discovery and development of antibacterial agents have been accelerated to replenish the arsenal of antibiotics which is limited and shrinking. In recent years, significant advances have achieved in the antibacterial area, including new compounds of known classes and new compounds with new mechanisms. This review summarizes these advances and provides perspective on future directions of antibacterial agents.

Automated summary

Antimicrobial resistance poses a global challenge as the effectiveness of old antibiotics diminishes. Discovery and development of antibacterial agents have been accelerated to replenish the limited and shrinking arsenal of antibiotics. Significant advances have been made in recent years in the antibacterial field, including new compounds of known classes and new compounds with new mechanisms.