4.8 Review

Lactoferrin, a multi-functional glycoprotein: Active therapeutic, drug nanocarrier & targeting ligand

Related references

Note: Only part of the references are listed.
Article Chemistry, Physical

The entry of nanoparticles into solid tumours

Shrey Sindhwani et al.

NATURE MATERIALS (2020)

Article Materials Science, Biomaterials

Inhalable Lactoferrin/Chondroitin-Functionalized Monoolein Nanocomposites for Localized Lung Cancer Targeting

Hadeer M. Abdelaziz et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2020)

Article Multidisciplinary Sciences

Combined chemo-magnetic field-photothermal breast cancer therapy based on porous magnetite nanospheres

Majid Sharifi et al.

SCIENTIFIC REPORTS (2020)

Article Medicine, General & Internal

Decreased salivary lactoferrin levels are specific to Alzheimer's disease

Marta Gonzalez-Sanchez et al.

EBIOMEDICINE (2020)

Article Medicine, Research & Experimental

A pilot study on the effect of lactoferrin on Alzheimer's disease pathological sequelae: Impact of the p-Akt/PTEN pathway

Waleed A. Mohamed et al.

BIOMEDICINE & PHARMACOTHERAPY (2019)

Article Biochemistry & Molecular Biology

Lactoferrin ameliorates dopaminergic neurodegeneration and motor deficits in MPTP-treated mice

Shuang-Feng Xu et al.

REDOX BIOLOGY (2019)

Review Biochemistry & Molecular Biology

Lactoferrin in Aseptic and Septic Inflammation

Maria Stefania Lepanto et al.

MOLECULES (2019)

Article Nanoscience & Nanotechnology

Dual-Targeted Lactoferrin Shell-Oily Core Nanocapsules for Synergistic Targeted/Herbal Therapy of Hepatocellular Carcinoma

Mona A. Abdelmoneem et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

Article Biochemistry & Molecular Biology

Behavioral and Biochemical Implications of Dendrimeric Rivastigmine in Memory-Deficit and Alzheimer's Induced Rodents

Avinash Gothwal et al.

ACS CHEMICAL NEUROSCIENCE (2019)

Article Biochemistry & Molecular Biology

Activation of TGF-β Canonical and Noncanonical Signaling in Bovine Lactoferrin-Induced Osteogenic Activity of C3H10T1/2 Mesenchymal Stem Cells

Yixuan Li et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Chemistry, Medicinal

Neuropharmacokinetic evaluation of lactoferrin-treated indinavir-loaded nanoemulsions: remarkable brain delivery enhancement

Zahra Karami et al.

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2019)

Article Materials Science, Biomaterials

Hyaluronic acid tethered pH-responsive alloy-drug nanoconjugates for multimodal therapy of glioblastoma: An intranasal route approach

Abhijeet Pandey et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2019)

Article Pharmacology & Pharmacy

Inhalable multi-compartmental phospholipid enveloped lipid core nanocomposites for localized mTOR inhibitor/herbal combined therapy of lung carcinoma

Dalia M. Kabary et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2018)

Article Pharmacology & Pharmacy

Self-assembled amphiphilic zein-lactoferrin micelles for tumor targeted co-delivery of rapamycin and wogonin to breast cancer

Sally A. Sabra et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2018)

Article Pharmacology & Pharmacy

Lactoferrin-decorated vs PEGylated zein nanospheres for combined aromatase inhibitor and herbal therapy of breast cancer

Sarah A. El-Lakany et al.

EXPERT OPINION ON DRUG DELIVERY (2018)

Article Chemistry, Multidisciplinary

Dual-targeted casein micelles as green nanomedicine for synergistic phytotherapy of hepatocellular carcinoma

Mona A. Abdelmoneem et al.

JOURNAL OF CONTROLLED RELEASE (2018)

Article Biotechnology & Applied Microbiology

Inhalable lactoferrin-chondroitin nanocomposites for combined delivery of doxorubicin and ellagic acid to lung carcinoma

Mahmoud M. Abd Elwakil et al.

NANOMEDICINE (2018)

Article Biotechnology & Applied Microbiology

Decorating protein nanospheres with lactoferrin enhances oral COX-2 inhibitor/herbal therapy of hepatocellular carcinoma

Mona A. Abdelmoneem et al.

NANOMEDICINE (2018)

Article Agriculture, Dairy & Animal Science

Effects of Recombinant Human Lactoferrin on Osteoblast Growth and Bone Status in Piglets

Qiuling Li et al.

ANIMAL BIOTECHNOLOGY (2018)

Article Biotechnology & Applied Microbiology

Optimization of desolvation process for fabrication of lactoferrin nanoparticles using quality by design approach

Abhijeet P. Pandey et al.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2017)

Review Obstetrics & Gynecology

Lactoferrin or ferrous salts for iron deficiency anemia in pregnancy: A meta-analysis of randomized trials

Hatem Abu Hashim et al.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2017)

Article Biochemistry & Molecular Biology

Lactoferrin nanoparticle mediated targeted delivery of 5-fluorouracil for enhanced therapeutic efficacy

Sonali Kumari et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2017)

Article Agriculture, Multidisciplinary

Biocompatible Polyelectrolyte Complex Nanoparticles from Lactoferrin and Pectin as Potential Vehicles for Antioxidative Curcumin

Jing-Kun Yan et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2017)

Article Materials Science, Biomaterials

Lactoferrin modified graphene oxide iron oxide nanocomposite for glioma-targeted drug delivery

Meng-Meng Song et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2017)

Article Chemistry, Medicinal

Preparation, characterization, and in vitro/vivo studies of oleanolic acid-loaded lactoferrin nanoparticles

Xiaojing Xia et al.

DRUG DESIGN DEVELOPMENT AND THERAPY (2017)

Article Materials Science, Biomaterials

Chlorin e6 loaded lactoferrin nanoparticles for enhanced photodynamic therapy

Mahesh G. Adimoolam et al.

JOURNAL OF MATERIALS CHEMISTRY B (2017)

Article Nanoscience & Nanotechnology

In Vitro Study of Receptor-Mediated Silica Nanoparticles Delivery across Blood-Brain Barrier

Yang Song et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

Article Biochemistry & Molecular Biology

Apoptotic effects of bovine apo-lactoferrin on HeLa tumor cells

Carla Luzi et al.

CELL BIOCHEMISTRY AND FUNCTION (2017)

Article Biochemistry & Molecular Biology

Role of CXC chemokine receptor type 4 as a lactoferrin receptor

Yoshiharu Takayama et al.

BIOCHEMISTRY AND CELL BIOLOGY (2017)

Editorial Material Biochemistry & Molecular Biology

Introduction to Nanomedicine

Didier Astruc

MOLECULES (2016)

Review Pharmacology & Pharmacy

Prevention of Necrotizing Enterocolitis Through Manipulation of the Intestinal Microbiota of the Premature Infant

Kannikar Vongbhavit et al.

CLINICAL THERAPEUTICS (2016)

Article Pharmacology & Pharmacy

Natural Polymeric Nanoparticles for Brain-Targeting: Implications on Drug and Gene Delivery

Ahmed O. Elzoghby et al.

CURRENT PHARMACEUTICAL DESIGN (2016)

Article Nanoscience & Nanotechnology

Intranasal delivery of rotigotine to the brain with lactoferrin-modified PEG-PLGA nanoparticles for Parkinson's disease treatment

Chenchen Bi et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2016)

Article Chemistry, Multidisciplinary

Silver-Lactoferrin Nanocomplexes as a Potent Antimicrobial Agent

Pawel Pomastowski et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

Article Biochemistry & Molecular Biology

Neuroprotective effect of curcumin-loaded lactoferrin nano particles against rotenone induced neurotoxicity

V. Satish Bollimpelli et al.

NEUROCHEMISTRY INTERNATIONAL (2016)

Review Physiology

THE FUNCTION OF V-ATPASES IN CANCER

Laura Stransky et al.

PHYSIOLOGICAL REVIEWS (2016)

Article Multidisciplinary Sciences

Triple combination MPT vaginal microbicide using curcumin and efavirenz loaded lactoferrin nanoparticles

Yeruva Samrajya Lakshmi et al.

SCIENTIFIC REPORTS (2016)

Article Pharmacology & Pharmacy

Lactoferrin- and antitransferrin-modified liposomes for brain targeting of the NK3 receptor agonist senktide: Preparation and in vivo evaluation

Maria Antonietta De Luca et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2015)

Article Clinical Neurology

In vitro and in vivo effect of human lactoferrin on glioblastoma growth

Antonietta Arcella et al.

JOURNAL OF NEUROSURGERY (2015)

Review Biochemistry & Molecular Biology

Multifunctional Iron Bound Lactoferrin and Nanomedicinal Approaches to Enhance Its Bioactive Functions

Jagat R. Kanwar et al.

MOLECULES (2015)

Article Nanoscience & Nanotechnology

Tumor regression following intravenous administration of lactoferrin- and lactoferricin-bearing dendriplexes

Li Ying Lim et al.

Nanomedicine-Nanotechnology Biology and Medicine (2015)

Article Nanoscience & Nanotechnology

In vivo toxicity of cationic micelles and liposomes

Kristina Bram Knudsen et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2015)

Article Biotechnology & Applied Microbiology

Principles of nanoparticle design for overcoming biological barriers to drug delivery

Elvin Blanco et al.

NATURE BIOTECHNOLOGY (2015)

Article Engineering, Biomedical

Effect of hydroxyapatite nanocrystals functionalized with lactoferrin in osteogenic differentiation of mesenchymal stem cells

Monica Montesi et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2015)

Article Chemistry, Applied

Sensitivity of emulsions stabilised by bovine β-casein and lactoferrin to heat and CaCl2

Noel A. McCarthy et al.

FOOD HYDROCOLLOIDS (2014)

Article Biochemistry & Molecular Biology

Carboplatin loaded protein nanoparticles exhibit improve anti-proliferative activity in retinoblastoma cells

Farhan Ahmed et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2014)

Article Nutrition & Dietetics

Dietary Bovine Lactoferrin Alters Mucosal and Systemic Immune Cell Responses in Neonatal Piglets

Sarah S. Comstock et al.

JOURNAL OF NUTRITION (2014)

Article Gastroenterology & Hepatology

Comparison of Bioactivities of Talactoferrin and Lactoferrins From Human and Bovine Milk

Rulan Jiang et al.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2014)

Article Medicine, Research & Experimental

Co-administration of Dual-Targeting Nanoparticles with Penetration Enhancement Peptide for Antiglioblastoma Therapy

Deyu Miao et al.

MOLECULAR PHARMACEUTICS (2014)

Article Oncology

Bovine Lactoferrin Induces Cell Cycle Arrest and Inhibits Mtor Signaling in Breast Cancer Cells

Yunlei Zhang et al.

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2014)

Article Multidisciplinary Sciences

Lactoferrin Deficiency Promotes Colitis-Associated Colorectal Dysplasia in Mice

Qiurong Ye et al.

PLOS ONE (2014)

Article Cell & Tissue Engineering

Enzymatically Cross-Linked Bovine Lactoferrin as Injectable Hydrogel for Cell Delivery

Ashley A. Amini et al.

TISSUE ENGINEERING PART A (2014)

Article Pharmacology & Pharmacy

Studies on lactoferrin nanoparticles of gambogic acid for oral delivery

Zhen-Hai Zhang et al.

DRUG DELIVERY (2013)

Article Food Science & Technology

Comparison of anticancer activity between lactoferrin nanoliposome and lactoferrin in Caco-2 cells in vitro

Jieqing Ma et al.

FOOD AND CHEMICAL TOXICOLOGY (2013)

Article Biochemistry & Molecular Biology

In Vitro and in Vivo Evaluation of Lactoferrin-Conjugated Liposomes as a Novel Carrier to Improve the Brain Delivery

Feng-Yun J. Huang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)

Review Biochemistry & Molecular Biology

Roles of lactoferrin on skin wound healing

Yoshiharu Takayama et al.

BIOCHEMISTRY AND CELL BIOLOGY (2012)

Article Chemistry, Multidisciplinary

Self-Assembled Polymersomes Conjugated with Lactoferrin as Novel Drug Carrier for Brain Delivery

Yuan Yu et al.

PHARMACEUTICAL RESEARCH (2012)

Article Chemistry, Multidisciplinary

Understanding the Evolution of Luminescent Gold Quantum Clusters in Protein Templates

Kamalesh Chaudhari et al.

ACS NANO (2011)

Article Pharmacology & Pharmacy

Lactoferrin modified doxorubicin-loaded procationic liposomes for the treatment of gliomas

Huali Chen et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2011)

Article Pharmacology & Pharmacy

Amino Group PEGylation of Bovine Lactoferrin by Linear Polyethylene Glycol-p-nitrophenyl Active Esters

Kanako Kato et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2010)

Article Biochemistry & Molecular Biology

Bovine lactoferrin inhibits Influenza A virus induced programmed cell death in vitro

Agostina Pietrantoni et al.

BIOMETALS (2010)

Article Biochemistry & Molecular Biology

Liposomalization of lactoferrin enhanced its anti-tumoral effects on melanoma cells

Anca Roseanu et al.

BIOMETALS (2010)

Review Biotechnology & Applied Microbiology

Recombinant human lactoferrin: A valuable protein for pharmaceutical products and functional foods

Celia Conesa et al.

BIOTECHNOLOGY ADVANCES (2010)

Article Pharmacology & Pharmacy

Lactoferrin-modified procationic liposomes as a novel drug carrier for brain delivery

Huali Chen et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2010)

Article Clinical Neurology

Gene therapy using lactoferrin-modified nanoparticles in a rotenone-induced chronic Parkinson model

Rongqin Huang et al.

JOURNAL OF THE NEUROLOGICAL SCIENCES (2010)

Article Medicine, Research & Experimental

Lactoferrin-Conjugated Biodegradable Polymersome Holding Doxorubicin and Tetrandrine for Chemotherapy of Glioma Rats

Zhiqing Pang et al.

MOLECULAR PHARMACEUTICS (2010)

Article Chemistry, Multidisciplinary

Luminescent quantum clusters of gold in transferrin family protein, lactoferrin exhibiting FRET

Paulrajpillai Lourdu Xavier et al.

NANOSCALE (2010)

Review Biochemistry & Molecular Biology

Immunomodulatory effects of lactoferrin on antigen presenting cells

Patrizia Puddu et al.

BIOCHIMIE (2009)

Review Biochemistry & Molecular Biology

A structural framework for understanding the multifunctional character of lactoferrin

Edward N. Baker et al.

BIOCHIMIE (2009)

Article Food Science & Technology

PEGylated lactoferrin enhanced its hepatoprotective effects on acute liver injury induced by carbon tetrachloride in rats

Akihiko Sugiyama et al.

FOOD AND CHEMICAL TOXICOLOGY (2009)

Review Infectious Diseases

Lactoferrin: structure, function and applications

Susana A. Gonzalez-Chavez et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2009)

Article Medicine, General & Internal

Bovine Lactoferrin Supplementation for Prevention of Late-Onset Sepsis in Very Low-Birth-Weight Neonates A Randomized Trial

Paolo Manzoni et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2009)

Article Biotechnology & Applied Microbiology

Neuroprotection in a 6-hydroxydopamine-lesioned Parkinson model using lactoferrin-modified nanoparticles

Rongqin Huang et al.

JOURNAL OF GENE MEDICINE (2009)

Article Chemistry, Multidisciplinary

Lactoferrin Conjugated with 40-kDa Branched Poly(ethylene Glycol) Has an Improved Circulating Half-Life

Yasuhiro Nojima et al.

PHARMACEUTICAL RESEARCH (2009)

Article Pharmacology & Pharmacy

Preparation and in Vitro Evaluation of Chitosan-coated Alginate/Calcium Complex Microparticles Loaded with Fluorescein-labeled Lactoferrin

Ken-ichi Koyama et al.

YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN (2009)

Article Biochemical Research Methods

Development of Poly(ethylene glycol) Conjugated Lactoferrin for Oral Administration

Yasuhiro Nojima et al.

BIOCONJUGATE CHEMISTRY (2008)

Article Surgery

Talactoferrin stimulates wound healing with modulation of inflammation

Jose Engelmayer et al.

JOURNAL OF SURGICAL RESEARCH (2008)

Article Nutrition & Dietetics

Bovine lactoferrin supplementation supports immune and antioxidant status in healthy human males

Ann M. Mulder et al.

NUTRITION RESEARCH (2008)

Review Veterinary Sciences

Lactoferrin: a review

L. Adlerova et al.

VETERINARNI MEDICINA (2008)

Article Gastroenterology & Hepatology

Effect of lactoferrin in patients with chronic hepatitis C: Combination therapy with interferon and ribavirin

Masahiko Kaito et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2007)

Article Pharmacology & Pharmacy

Formulation and evaluation of lactoferrin bioadhesive tablets

Y. Takahashi et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2007)

Article Immunology

Uptake of ingested bovine lactoferrin and its accumulation in adult mouse tissues

Romy Fischer et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2007)

Article Chemistry, Medicinal

Preparation and in vitro characteristics of lactoferrin-loaded chitosan microparticles

Hiraku Onishi et al.

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2007)

Article Biochemistry & Molecular Biology

Human lactoferrin controls the level of retinoblastoma protein and its activity

Hee-Joung Son et al.

BIOCHEMISTRY AND CELL BIOLOGY (2006)

Article Medicine, General & Internal

Amoebicidal Activity of Milk, Apo-lactoferrin, sIgA and Lysozyme

Nidia Leon-Sicairos et al.

CLINICAL MEDICINE & RESEARCH (2006)

Review Biochemistry & Molecular Biology

Multifunctional roles of lactoferrin: a critical overview

PP Ward et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2005)

Review Biochemistry & Molecular Biology

Lactoferrin: an important host defence against microbial and viral attack

P Valenti et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2005)

Review Biochemistry & Molecular Biology

Mammalian lactoferrin receptors:: structure and function

YA Suzuki et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2005)

Review Biochemistry & Molecular Biology

Lactoferrin: a modulator of immune and inflammatory responses

D Legrand et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2005)

Article Pharmacology & Pharmacy

Liposomalization of lactoferrin enhanced it's anti-inflammatory effects via oral administration

A Ishikado et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2005)

Review Pharmacology & Pharmacy

New technologies for drug delivery across the blood brain barrier

AV Kabanov et al.

CURRENT PHARMACEUTICAL DESIGN (2004)

Article Biochemistry & Molecular Biology

Cellular internalization of lactoferrin in intestinal epithelial cells

K Ashida et al.

BIOMETALS (2004)

Article Microbiology

Bovine lactoferrin inhibits adenovirus infection by interacting with viral structural polypeptides

A Pietrantoni et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2003)

Article Biochemistry & Molecular Biology

Caspase 3 activation is essential for efficient influenza virus propagation

WJ Wurzer et al.

EMBO JOURNAL (2003)

Article Agriculture, Multidisciplinary

Cold-set globular protein gels: Interactions, structure and rheology as a function of protein concentration

AC Altlng et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Iron status in mice carrying a targeted disruption of lactoferrin

PP Ward et al.

MOLECULAR AND CELLULAR BIOLOGY (2003)

Article Biochemistry & Molecular Biology

Identification of an import signal for, and the nuclear localization of, human lactoferrin

S Penco et al.

BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY (2001)

Article Nutrition & Dietetics

Gastric digestion of bovine lactoferrin in vivo in adults

FJ Troost et al.

JOURNAL OF NUTRITION (2001)