Journal
BIOINFORMATICS
Volume 36, Issue 22-23, Pages 5522-5523Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btaa1047
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Funding
- Italian Ministero dell'Universita e Ricerca: PRIN
- Consiglio Nazionale delle Ricerche
- H2020 projects [824087, 857650, 871075]
- Elixir-IIB
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The Summary: While over 200 000 genomic sequences are currently available through dedicated repositories, ad hoc methods for the functional annotation of SARS-CoV-2 genomes do not harness all currently available resources for the annotation of functionally relevant genomic sites. Here, we present CorGAT, a novel tool for the functional annotation of SARS-CoV-2 genomic variants. By comparisons with other state of the art methods we demonstrate that, by providing a more comprehensive and rich annotation, our method can facilitate the identification of evolutionary patterns in the genome of SARS-CoV-2.
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