Related references
Note: Only part of the references are listed.The enhancement of glycolysis regulates pancreatic cancer metastasis
Jinshou Yang et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2020)
Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib
Greta Bagnolini et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Rad51/BRCA2 disruptors inhibit homologous recombination and synergize with olaparib in pancreatic cancer cells
Marinella Roberti et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
A decade of clinical development of PARP inhibitors in perspective
J. Mateo et al.
ANNALS OF ONCOLOGY (2019)
Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma
Choh Yeung et al.
CANCER RESEARCH (2019)
Targeting cancer metabolism to develop human lactate dehydrogenase (hLDH)5 inhibitors
Shao-Lin Zhang et al.
DRUG DISCOVERY TODAY (2018)
Mechanisms of PARP inhibitor sensitivity and resistance
Alan D. D'Andrea
DNA REPAIR (2018)
Shutting down the power supply for DNA repair in cancer cells
Marcel A. T. M. van Vugt
JOURNAL OF CELL BIOLOGY (2017)
Olaparib in combination with irinotecan, cisplatin, and mitomycin C in patients with advanced pancreatic cancer
Mark Yarchoan et al.
ONCOTARGET (2017)
Synthetic Lethality Triggered by Combining Olaparib with BRCA2-Rad51 Disruptors
Federico Falchi et al.
ACS CHEMICAL BIOLOGY (2017)
Stimulation of lactate receptor (HCAR1) affects cellular DNA repair capacity
Waldemar Wagner et al.
DNA REPAIR (2017)
Phase II Study of Olaparib (AZD-2281) After Standard Systemic Therapies for Disseminated Colorectal Cancer
Lawrence Leichman et al.
ONCOLOGIST (2016)
Metabolic Enzymes Moonlighting in the Nucleus: Metabolic Regulation of Gene Transcription
Aristeidis E. Boukouris et al.
TRENDS IN BIOCHEMICAL SCIENCES (2016)
Transient elevation of glycolysis confers radio-resistance by facilitating DNA repair in cells
Anant Narayan Bhatt et al.
BMC CANCER (2015)
Targeting homologous recombination, new pre-clinical and clinical therapeutic combinations inhibiting RAD51
Ambber Ward et al.
CANCER TREATMENT REVIEWS (2015)
L- and D-lactate enhance DNA repair and modulate the resistance of cervical carcinoma cells to anticancer drugs via histone deacetylase inhibition and hydroxycarboxylic acid receptor 1 activation
Waldemar Wagner et al.
CELL COMMUNICATION AND SIGNALING (2015)
Lactate dehydrogenase inhibitors sensitize lymphoma cells to cisplatin without enhancing the drug effects on immortalized normal lymphocytes
Marcella Manerba et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2015)
Cancer as a metabolic disease: implications for novel therapeutics
Thomas N. Seyfried et al.
CARCINOGENESIS (2014)
Germline and Somatic Mutations in Homologous Recombination Genes Predict Platinum Response and Survival in Ovarian, Fallopian Tube, and Peritoneal Carcinomas
Kathryn P. Pennington et al.
CLINICAL CANCER RESEARCH (2014)
Targeting homologous recombination-mediated DNA repair in cancer
Joao F. S. Carvalho et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2014)
Inhibition of lactate dehydrogenase activity as an approach to cancer therapy
Luigi Fiume et al.
FUTURE MEDICINAL CHEMISTRY (2014)
Inhibition of LDH-A by oxamate induces G2/M arrest, apoptosis and increases radiosensitivity in nasopharyngeal carcinoma cells
Xiaoming Zhai et al.
ONCOLOGY REPORTS (2013)
Galloflavin, a new lactate dehydrogenase inhibitor, induces the death of human breast cancer cells with different glycolytic attitude by affecting distinct signaling pathways
F. Farabegoli et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2012)
Knockdown of lactate dehydrogenase A suppresses tumor growth and metastasis of human hepatocellular carcinoma
Shi L. Sheng et al.
FEBS JOURNAL (2012)
Histone deacetylase inhibitor potentiates chemotherapy-induced apoptosis through Bim upregulation in Burkitt's lymphoma cells
Ana Carolina dos Santos Ferreira et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2012)
Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
Sophia Y. Lunt et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)
Overcoming Trastuzumab Resistance in Breast Cancer by Targeting Dysregulated Glucose Metabolism
Yuhua Zhao et al.
CANCER RESEARCH (2011)
Nonhomologous end joining drives poly(ADP-ribose) polymerase (PARP) inhibitor lethality in homologous recombination-deficient cells
Anand G. Patel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
ATM Is a Redox Sensor Linking Genome Stability and Carbon Metabolism
Antje Krueger et al.
SCIENCE SIGNALING (2011)
Warburg effect in chemosensitivity: Targeting lactate dehydrogenase-A re-sensitizes Taxol-resistant cancer cells to Taxol
Ming Zhou et al.
MOLECULAR CANCER (2010)
Cellular Responses to Cisplatin-Induced DNA Damage
Alakananda Basu et al.
JOURNAL OF NUCLEIC ACIDS (2010)
Histone 2B (H2B) expression is confined to a proper NAD+/NADH redox status
Ru-Ping Dai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Why do cancers have high aerobic glycolysis?
RA Gatenby et al.
NATURE REVIEWS CANCER (2004)
Role of BRCA2 in control of the RAD51 recombination and DNA repair protein
AA Davies et al.
MOLECULAR CELL (2001)