4.3 Article

Alkaloids from the leaves of Isatis indigotica fortune and their chemotaxonomic significance

Journal

BIOCHEMICAL SYSTEMATICS AND ECOLOGY
Volume 93, Issue -, Pages -

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bse.2020.104163

Keywords

Isatis indigotica Fortune; Alkaloids; Chemotaxonomy

Funding

  1. Natural Science Foundation of Inner Mongolia [2019BS08017]
  2. Doctoral Scientific Research Foundation of Inner Mongolia University for Nationalities [B S464]

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From the leaves of Isatis indigotica Fortune, one new alkaloid, namely (2E)-N-(2-hydroxyphenyl)-2-(1-hydroxy-3oxoindolin-2-ylidene) acetamide (1), together with four known ones, such as phaitanthrin D (2), methyl quindoline-11-carboxylate (3), cephalandole B (4) and 2,2-di (3-indolyl)-3-indolone (5) were isolated and identified. The structure of compound 1 was elucidated by means of spectroscopic analysis, including HRESIMS together with 1D and 2D NMR experiments. Compounds 1, 2 and 5 were obtained from this genus for the first time. Chemotaxonomic significance of these compounds is described herein.

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