4.6 Article

High-resolution X-ray structure of three microtubule-stabilizing agents in complex with tubulin provide a rationale for drug design

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Dynamic and asymmetric fluctuations in the microtubule wall captured by high-resolution cryoelectron microscopy

Garrett E. Debs et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Biochemistry & Molecular Biology

Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site Ligands

Francisco de Asis Balaguer et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Chemistry, Medicinal

Current advances of tubulin inhibitors as dual acting small molecules for cancer therapy

Kinsie E. Arnst et al.

MEDICINAL RESEARCH REVIEWS (2019)

Review Cell Biology

Microtubule-Targeting Agents: Strategies To Hijack the Cytoskeleton

Michel O. Steinmetz et al.

TRENDS IN CELL BIOLOGY (2018)

Article Multidisciplinary Sciences

Mechanism of microtubule stabilization by taccalonolide AJ

Yuxi Wang et al.

NATURE COMMUNICATIONS (2017)

Article Biochemistry & Molecular Biology

Structural Basis of Microtubule Stabilization by Discodermolide

Andrea E. Prota et al.

CHEMBIOCHEM (2017)

Review Cell Biology

Control of microtubule organization and dynamics: two ends in the limelight

Anna Akhmanova et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)

Article Chemistry, Multidisciplinary

Structural Basis of Microtubule Stabilization by Laulimalide and Peloruside A

Andrea E. Prota et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

Review Biochemistry & Molecular Biology

Recent progress with microtubule stabilizers: new compounds, binding modes and cellular activities

Cristina C. Rohena et al.

NATURAL PRODUCT REPORTS (2014)

Article Multidisciplinary Sciences

Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents

Andrea E. Prota et al.

SCIENCE (2013)

Article Multidisciplinary Sciences

Linking Crystallographic Model and Data Quality

P. Andrew Karplus et al.

SCIENCE (2012)

Article Biochemical Research Methods

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Paul D. Adams et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)

Review Biotechnology & Applied Microbiology

Microtubule-binding agents: a dynamic field of cancer therapeutics

Charles Dumontet et al.

NATURE REVIEWS DRUG DISCOVERY (2010)

Review Oncology

Discovery of Ixabepilone

John T. Hunt

MOLECULAR CANCER THERAPEUTICS (2009)

Article Oncology

The epothilones: Translating from the laboratory to the clinic

James J. Lee et al.

CLINICAL CANCER RESEARCH (2008)

Article Chemistry, Multidisciplinary

Phaser crystallographic software

Airlie J. McCoy et al.

JOURNAL OF APPLIED CRYSTALLOGRAPHY (2007)

Review Oncology

Microtubules as a target for anticancer drugs

MA Jordan et al.

NATURE REVIEWS CANCER (2004)

Article Multidisciplinary Sciences

The binding mode of epothilone A on α,β-tubulin by electron crystallography

JH Nettles et al.

SCIENCE (2004)

Article Biochemical Research Methods

Coot:: model-building tools for molecular graphics

P Emsley et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)