4.6 Article

Coptisine induces autophagic cell death through down-regulation of PI3K/Akt/mTOR signaling pathway and up-regulation of ROS-mediated mitochondrial dysfunction in hepatocellular carcinoma Hep3B cells

Related references

Note: Only part of the references are listed.
Article Plant Sciences

Coptisine suppresses proliferation and inhibits metastasis in human pancreatic cancer PANC-1 cells

Ya-Li Zhang et al.

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2020)

Review Biochemistry & Molecular Biology

Selective Autophagy in Normal and Malignant Hematopoiesis

Sebastian E. Koschade et al.

JOURNAL OF MOLECULAR BIOLOGY (2020)

Review Gastroenterology & Hepatology

Tumour evolution in hepatocellular carcinoma

Amanda J. Craig et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2020)

Article Biochemistry & Molecular Biology

Induction of Apoptosis by Coptisine in Hep3B Hepatocellular Carcinoma Cells through Activation of the ROS-Mediated JNK Signaling Pathway

So Young Kim et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Toxicology

Myristoylated TMEM39AS41, a cell-permeable peptide, causes lung cancer cell death

Sungjin Park et al.

TOXICOLOGICAL RESEARCH (2020)

Review Biotechnology & Applied Microbiology

Targeting PI3K/AKT/mTOR-mediated autophagy for tumor therapy

Zhenru Xu et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2020)

Review Medical Laboratory Technology

Autophagy and its role in gastric cancer

Yijing Cao et al.

CLINICA CHIMICA ACTA (2019)

Article Biochemistry & Molecular Biology

Quercetin inhibits growth of hepatocellular carcinoma by apoptosis induction in part via autophagy stimulation in mice

Yi Ji et al.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2019)

Review Medicine, General & Internal

Hepatocellular Carcinoma: Molecular Mechanisms and Targeted Therapies

Ali Alqahtani et al.

MEDICINA-LITHUANIA (2019)

Review Oncology

Sestrins as a Therapeutic Bridge between ROS and Autophagy in Cancer

Miguel Sanchez-Alvarez et al.

CANCERS (2019)

Review Cell Biology

Coptisine from Coptis chinensis exerts diverse beneficial properties: A concise review

Jiasi Wu et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2019)

Article Biochemistry & Molecular Biology

Molecular Regulation Mechanisms and Interactions Between Reactive Oxygen Species and Mitophagy

Pan Fan et al.

DNA AND CELL BIOLOGY (2019)

Article Multidisciplinary Sciences

Melatonin: The smart molecule that differentially modulates autophagy in tumor and normal placental cells

Lucas Sagrillo-Fagundes et al.

PLOS ONE (2019)

Review Biology

Autophagy in Cancer Cell Death

Benedikt Linder et al.

BIOLOGY-BASEL (2019)

Article Pharmacology & Pharmacy

Modulating autophagy in cancer therapy: Advancements and challenges for cancer cell death sensitization

Punya Bhat et al.

BIOCHEMICAL PHARMACOLOGY (2018)

Article Medicine, Research & Experimental

Coptisine from Rhizoma coptidis exerts an anti-cancer effect on hepatocellular carcinoma by up-regulating miR-122

Fang-Ni Chai et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

Review Oncology

Pro-survival autophagy and cancer cell resistance to therapy

Chandan Kanta Das et al.

CANCER AND METASTASIS REVIEWS (2018)

Article Oncology

Phytochemicals as potent modulators of autophagy for cancer therapy

Mohammad Amin Moosavi et al.

CANCER LETTERS (2018)

Review Medicine, General & Internal

Hepatocellular carcinoma: Present and future

Carolina Armengol et al.

MEDICINA CLINICA (2018)

Review Cell Biology

Mechanism and medical implications of mammalian autophagy

Ivan Dikic et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)

Review Gastroenterology & Hepatology

The role of ROS-induced autophagy in hepatocellular carcinoma

Xingxing Yuan et al.

CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY (2018)

Review Integrative & Complementary Medicine

Cellular stress response mechanisms of Rhizoma coptidis: a systematic review

Jin Wang et al.

CHINESE MEDICINE (2018)

Review Oncology

mTOR Pathways in Cancer and Autophagy

Mathieu Paquette et al.

CANCERS (2018)

Review Cell Biology

Autophagy-dependent cell death - where, how and why a cell eats itself to death

Shani Bialik et al.

JOURNAL OF CELL SCIENCE (2018)

Review Biochemistry & Molecular Biology

AMPK: Regulation of Metabolic Dynamics in the Context of Autophagy

Isaac Tamargo-Gomez et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Gastroenterology & Hepatology

Autophagy and liver cancer

Yunus Akkoc et al.

TURKISH JOURNAL OF GASTROENTEROLOGY (2018)

Review Biochemistry & Molecular Biology

Understanding the Effectiveness of Natural Compound Mixtures in Cancer through Their Molecular Mode of Action

Thazin Nwe Aung et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Biochemistry & Molecular Biology

Coptisine protects cardiomyocyte against hypoxia/reoxygenation-induced damage via inhibition of autophagy

Yahui Wang et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)

Review Biochemistry & Molecular Biology

Activation of apoptosis signalling pathways by reactive oxygen species

Maureen Redza-Dutordoir et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2016)

Review Biochemistry & Molecular Biology

p62 in Cancer: Signaling Adaptor Beyond Autophagy

Jorge Moscat et al.

Article Multidisciplinary Sciences

Activation of the AMPK-ULK1 pathway plays an important role in autophagy during prion infection

Xue-Yu Fan et al.

SCIENTIFIC REPORTS (2015)

Review Biochemistry & Molecular Biology

Interplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapy

Laura Poillet-Perez et al.

REDOX BIOLOGY (2015)

Article Oncology

The AMPK Inhibitor Compound C Is a Potent AMPK-Independent Antiglioma Agent

Xiaona Liu et al.

MOLECULAR CANCER THERAPEUTICS (2014)

Article Agriculture, Multidisciplinary

Allicin Induces Anti-human Liver Cancer Cells through the p53 Gene Modulating Apoptosis and Autophagy

Yung-Lin Chu et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2013)

Article Biochemistry & Molecular Biology

Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK-dependent activation of autophagy

D. Vara et al.

CELL DEATH AND DIFFERENTIATION (2011)

Article Cell Biology

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Joungmok Kim et al.

NATURE CELL BIOLOGY (2011)

Article Gastroenterology & Hepatology

Pivotal Role of mTOR Signaling in Hepatocellular Carcinoma

Augusto Villanueva et al.

GASTROENTEROLOGY (2008)

Article Oncology

mTOR and P70S6 kinase expression in primary liver neoplasms

F Sahin et al.

CLINICAL CANCER RESEARCH (2004)

Review Neurosciences

Mitochondrial formation of reactive oxygen species

JF Turrens

JOURNAL OF PHYSIOLOGY-LONDON (2003)

Article Biochemistry & Molecular Biology

Mitochondrial free radical generation, oxidative stress, and aging

E Cadenas et al.

FREE RADICAL BIOLOGY AND MEDICINE (2000)