4.7 Article

AI-assisted CT imaging analysis for COVID-19 screening: Building and deploying a medical AI system

Journal

APPLIED SOFT COMPUTING
Volume 98, Issue -, Pages -

Publisher

ELSEVIER
DOI: 10.1016/j.asoc.2020.106897

Keywords

COVID-19; Deep learning; Neural network; Medical assistance system; Classification; Segmentation

Funding

  1. National Key Research and Development Program of China [2020YFC0845500]
  2. National Natural Science Foundation of China (NSFC) [61532001]
  3. Tsinghua Initiative Research Program [20151080475]
  4. Application for Independent Research Project of Tsinghua University (Project Against SARI)

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This paper presents the experience of building and deploying an AI system for rapid detection of COVID-19 pneumonia, which can save time for physicians and improve the performance of COVID-19 detection. The authors overcame various challenges in a interdisciplinary team and successfully deployed the system in four weeks.
The sudden outbreak of novel coronavirus 2019 (COVID-19) increased the diagnostic burden of radiologists. In the time of an epidemic crisis, we hope artificial intelligence (AI) to reduce physician workload in regions with the outbreak, and improve the diagnosis accuracy for physicians before they could acquire enough experience with the new disease. In this paper, we present our experience in building and deploying an AI system that automatically analyzes CT images and provides the probability of infection to rapidly detect COVID-19 pneumonia. The proposed system which consists of classification and segmentation will save about 30%-40% of the detection time for physicians and promote the performance of COVID-19 detection. Specifically, working in an interdisciplinary team of over 30 people with medical and/or AI background, geographically distributed in Beijing and Wuhan, we are able to overcome a series of challenges (e.g. data discrepancy, testing time-effectiveness of model, data security, etc.) in this particular situation and deploy the system in four weeks. In addition, since the proposed AI system provides the priority of each CT image with probability of infection, the physicians can confirm and segregate the infected patients in time. Using 1,136 training cases (723 positives for COVID-19) from five hospitals, we are able to achieve a sensitivity of 0.974 and specificity of 0.922 on the test dataset, which included a variety of pulmonary diseases. (C) 2020 Elsevier B.V. All rights reserved.

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