Journal
DALTON TRANSACTIONS
Volume 45, Issue 7, Pages 2762-2771Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5dt04338g
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Funding
- Hong Kong Baptist University [FRG2/14-15/004]
- Health and Medical Research Fund [HMRF/14130522]
- Research Grants Council [HKBU/201811, HKBU/204612, HKBU/201913]
- French National Research Agency/Research Grants Council Joint Research Scheme [A-HKBU201/12]
- National Natural Science Foundation of China [21575121]
- Guangdong Province Natural Science Foundation [2015A030313816]
- Hong Kong Baptist University Century Club Sponsorship Scheme
- Interdisciplinary Research Matching Scheme [RC-IRMS/14-15/06]
- Inter-institutional Collaborative Research Scheme [RC-ICRS/15-16/02A]
- State Key Laboratory of Synthetic Chemistry
- Science and Technology Development Fund, Macao SAR [103/2012/A3]
- University of Macau [MYRG091(Y3-L2)-ICMS12-LCH, MYRG2015-00137-ICMS-QRCM, MRG023/LCH/2013/ICMS, MRG044/LCH/2015/ICMS]
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The landscape of inorganic medicinal chemistry has been dominated by the investigation of platinum, and to a lesser extent ruthenium, complexes over the past few decades. Recently, complexes based on other metal centers such as rhodium have attracted attention due to their tunable chemical and biological properties as well as distinct mechanisms of action. This perspective highlights recent examples of rhodium complexes that show diverse biological activities against various targets, including enzymes and protein-protein interactions.
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