Factors Associated with Mortality among Hospitalized Patients with COVID-19: A Retrospective Cohort Study

Information on the risk factors for COVID-19 mortality in lowand middle-income countries is still scarce. In this retrospective cohort study, we analyzed the factors associated with COVID-19 mortality in hospitalized patients in a poor area of Brazil. Logistic regression was used to identify factors independently associated with mortality, including gender, age, and the presence of underlying medical conditions. A total of 1,207 patients were included in the analysis, and a 1.5-fold increase in COVID-19 mortality was found among patients aged > 65 years with hypertension and diabetes (odds ratio [OR]: 1.50, 95% CI: 1.02-2.19). Moreover, infectious disease (OR: 4.31, 95% CI: 1.39-13.39), kidney disease (OR: 2.59, 95% CI: 1.27-5.27), and heart disease (OR: 2.00, 95% CI: 1.31-3.04) were also predictive for COVID-19 in hospital death. This large cohort provides important data on potential factors associated with COVID-19 mortality in Brazil.

Automated summary

This study analyzed factors associated with COVID-19 mortality in hospitalized patients in a poor area of Brazil, finding a 1.5-fold increase in mortality among patients aged > 65 years with hypertension and diabetes. Infectious, kidney, and heart diseases were also predictive factors for COVID-19 hospital death. The large cohort provided important data on potential factors associated with COVID-19 mortality in Brazil.